Title: Cheap Car Hire in Santo Domingo, PAN - Expedia.co.uk [Santo Domingo Travel Guide](https://expedia.co.uk/Santo-Domingo.dx553248623199120260)[Hotels in Santo Domingo](https://expedia.co.uk/Santo-Domingo-Hotels.d553248623199120260.Travel-Guide-Hotels)[Flights to Santo Domingo](https://expedia.co.uk/Cheap-Flights-To-Santo-Domingo.d553248623199120260.Travel-Guide-Flights)[Santo Domingo Holidays](https://expedia.co.uk/Santo-Domingo.d553248623199120260.Holidays-City-Breaks) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Santo Domingo, PAN ## Search and Compare from Car Companies in Santo Domingo ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Santo Domingo \* Price found within the past 6 days. Click for updated prices. Wed, 4 Mar - Thu, 5 Mar ### Mini Kia Picanto or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location Paseo Enrique Genzier, Chitre 0831-02510, PAN 21.4 mi from Santo Domingo city centre ![Kia Picanto](//mediaim.expedia.com/cars/35/3b2715b0-4551-4f0d-9ed6-e588b6cc1c65.jpg) #### £24 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.965607&olon=-80.435860&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=24.06&cvrfrr=SX&ctrfrr=MC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22mini%22]) Wed, 4 Mar - Thu, 5 Mar ### Economy Hyundai I10 Grand or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location Paseo Enrique Genzier, Chitre 0831-02510, PAN 21.4 mi from Santo Domingo city centre ![Hyundai I10 Grand](//mediaim.expedia.com/cars/35/a9f0ca28-73b5-4de1-9324-bed0d500dfeb.jpg) #### £25 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.965607&olon=-80.435860&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=24.92&cvrfrr=SX&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Wed, 4 Mar - Thu, 5 Mar ### Compact Hyundai Accent or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location Paseo Enrique Genzier, Chitre 0831-02510, PAN 21.4 mi from Santo Domingo city centre ![Hyundai Accent](//mediaim.expedia.com/cars/35/07899aad-0a9d-4f00-a1aa-138413748a93.jpg) #### £26 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.965607&olon=-80.435860&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=25.83&cvrfrr=SX&ctrfrr=CD&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Wed, 4 Mar - Thu, 5 Mar ### Midsize Kia Rio or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location Paseo Enrique Genzier, Chitre 0831-02510, PAN 21.4 mi from Santo Domingo city centre ![Kia Rio](//mediaim.expedia.com/cars/35/bc174f79-96e1-45bf-8960-53b83266ef66.jpg) #### £27 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.965607&olon=-80.435860&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=26.75&cvrfrr=SX&ctrfrr=ID&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Wed, 4 Mar - Thu, 5 Mar ### Standard Hyundai Accent Solaris or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location Paseo Enrique Genzier, Chitre 0831-02510, PAN 21.4 mi from Santo Domingo city centre ![Hyundai Accent Solaris](//mediaim.expedia.com/cars/35/700808d8-afde-418e-b977-398745174901.jpg) #### £28 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.965607&olon=-80.435860&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=27.67&cvrfrr=SX&ctrfrr=SD&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Wed, 4 Mar - Thu, 5 Mar ### Full Size Hyundai Elantra or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location Paseo Enrique Geenzier, Chitre, PAN 21.56 mi from Santo Domingo city centre ![Hyundai Elantra](//mediaim.expedia.com/cars/41/1a66a681-e401-4628-b1b5-9cd373624b1c.jpg) #### £44 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.966056&olon=-80.438830&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=43.62&cvrfrr=ZI&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Wed, 4 Mar - Thu, 5 Mar ### Premium Ford Fusion or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location Paseo Enrique Geenzier, Chitre, PAN 21.56 mi from Santo Domingo city centre ![Ford Fusion](//mediaim.expedia.com/cars/41/426b9248-a243-4f5f-adbd-8d88aa4d9a82.jpg) #### £56 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.966056&olon=-80.438830&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=56.31&cvrfrr=ZI&ctrfrr=PC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22premium%22]) Wed, 4 Mar - Thu, 5 Mar ### Luxury SUV Toyota Prado or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location Paseo Enrique Geenzier, Chitre, PAN 21.56 mi from Santo Domingo city centre ![Toyota Prado](//mediaim.expedia.com/cars/41/6cb1c1ce-06a8-4f0a-8e02-a76a86798aea.jpg) #### £88 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=7.966056&olon=-80.438830&date1=04/03/2026&date2=05/03/2026&pprfrr=null&tprfrr=88.03&cvrfrr=ZI&ctrfrr=LF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Santo Domingo [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santo%20Domingo,%20Los%20Santos,%20Panama&dpln=553248623199120260&date1=09/03/2026&date2=11/03/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 2 days. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=CTG_SPRING_PROMO_553248623199120260) ## Frequently asked questions ### How much is a rental car per day in Santo Domingo? ### What happens if I need to cancel my Santo Domingo car reservation? ### What types of cars can I rent in Santo Domingo? ### Where can I go on a road trip from Santo Domingo? > - Around 100 miles from Santo Domingo, San Miguelito is a must-do for many visitors. With sights like Metromall Panama, you'll have no shortage of things to keep you busy here. > - Another destination that's a hit with travellers is Colon, around 110 miles away. Colon 2000 is just one of many reasons why people keep returning. > - No road trip is complete without a wander around Red Frog Beach. This well-known nature spot is roughly 170 miles from Santo Domingo. Enjoy the fresh air and relax! ### How do I find the best car hire deals in Santo Domingo with Expedia? ### What do you need to rent a car in Santo Domingo? ### What is the cheapest car hire in Santo Domingo? ### Can I hire a car for a month or longer in Santo Domingo? ### Where can I find a Santo Domingo hire car if I am younger than 25? ### Why should I rent a Santo Domingo car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | £24 | | Our second best deal of the day: | £25 | | Our third best deal of the day: | £26 | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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