Title: Cheap Car Hire in Murphysboro, USA - Expedia.co.uk [Murphysboro Travel Guide](https://expedia.co.uk/Murphysboro.dx55857)[Hotels in Murphysboro](https://expedia.co.uk/Murphysboro-Hotels.d55857.Travel-Guide-Hotels)[Flights to Murphysboro](https://expedia.co.uk/Cheap-Flights-To-Murphysboro.d55857.Travel-Guide-Flights)[Murphysboro Holidays](https://expedia.co.uk/Murphysboro.d55857.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6186677/653cb0cf-de6f-4f9e-a73f-18858257194c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Murphysboro, USA ## Search and Compare from Car Companies in Murphysboro Photo by Southernmost Illinois Tourism Bureau ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Murphysboro \* Price found within the past 6 days. Click for updated prices. Wed, 11 Feb - Thu, 12 Feb ### Midsize Mazda 3 4-door or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) #### Pick-up location 10400 Terminal Dr #105, Marion, Illinois 62959, USA 17.44 mi from Murphysboro city centre ![Mazda 3 4-door](//mediaim.expedia.com/cars/40/4d18581d-6ea9-41f9-8ee1-b30c8c1d3cfc.jpg) #### £42 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=37.746697&olon=-89.010668&date1=11/02/2026&date2=12/02/2026&pprfrr=null&tprfrr=42.44&cvrfrr=ZE&ctrfrr=IC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Wed, 11 Feb - Thu, 12 Feb ### Compact Ford Focus or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) #### Pick-up location 10400 Terminal Dr #105, Marion, Illinois 62959, USA 17.44 mi from Murphysboro city centre ![Ford Focus](//mediaim.expedia.com/cars/40/b0b0d176-5217-4b23-9e8d-d49ee10835ec.jpg) #### £42 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=37.746697&olon=-89.010668&date1=11/02/2026&date2=12/02/2026&pprfrr=null&tprfrr=42.44&cvrfrr=ZE&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Wed, 11 Feb - Thu, 12 Feb ### Economy Chevrolet Spark or similar - 4 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) #### Pick-up location 10400 Terminal Dr #105, Marion, Illinois 62959, USA 17.44 mi from Murphysboro city centre ![Chevrolet Spark](//mediaim.expedia.com/cars/40/325297f9-cf83-4ce9-9eb1-a6032b62a34e.jpg) #### £42 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=37.746697&olon=-89.010668&date1=11/02/2026&date2=12/02/2026&pprfrr=null&tprfrr=42.44&cvrfrr=ZE&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Wed, 11 Feb - Thu, 12 Feb ### Full Size Chevrolet Malibu or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) #### Pick-up location 10400 Terminal Dr #105, Marion, Illinois 62959, USA 17.44 mi from Murphysboro city centre ![Chevrolet Malibu](//mediaim.expedia.com/cars/40/1290a4c0-23ef-46ad-b34d-e3f26aab3b6c.jpg) #### £47 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=37.746697&olon=-89.010668&date1=11/02/2026&date2=12/02/2026&pprfrr=null&tprfrr=47.44&cvrfrr=ZE&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Wed, 11 Feb - Thu, 12 Feb ### Standard SUV Chevrolet Equinox or similar - 5 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) #### Pick-up location 10400 Terminal Dr #105, Marion, Illinois 62959, USA 17.44 mi from Murphysboro city centre ![Chevrolet Equinox](//mediaim.expedia.com/cars/40/3374f66b-6921-4e9d-a7f6-79f747de841a.jpg) #### £61 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=37.746697&olon=-89.010668&date1=11/02/2026&date2=12/02/2026&pprfrr=null&tprfrr=60.73&cvrfrr=ZE&ctrfrr=SF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Wed, 11 Feb - Thu, 12 Feb ### Mini Van CHRYSLER PACIFICA or similar - 7 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) #### Pick-up location 10400 Terminal Dr #105, Marion, Illinois 62959, USA 17.44 mi from Murphysboro city centre ![CHRYSLER PACIFICA](//mediaim.expedia.com/cars/40/fa7b40ac-31b6-4a2b-8c39-f9d06089df5f.jpg) #### £71 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=37.746697&olon=-89.010668&date1=11/02/2026&date2=12/02/2026&pprfrr=null&tprfrr=71.25&cvrfrr=ZE&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) ### Don't see what you're looking for? See all car hire in Murphysboro [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Murphysboro,%20Illinois,%20United%20States%20of%20America&dpln=55857&date1=14/02/2026&date2=16/02/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 2 days. Prices and availability subject to change. Additional terms may apply. ## Frequently asked questions ### How much is a rental car per day in Murphysboro? ### What happens if I need to cancel my Murphysboro car reservation? ### What types of cars can I rent in Murphysboro? ### Where can I go on a road trip from Murphysboro? > - Home to sights and activities galore, St. Louis is approximately 75 miles from Murphysboro. First stop? Make a beeline for Busch Stadium, one of the city's biggest highlights. > - Another city that's a hit with travellers is Evansville, around 95 miles away. Ford Centre is just one of the many reasons people love coming here. > - No trip is complete without taking in Mammoth Cave National Park. This renowned nature spot is approximately 180 miles from Murphysboro. Relax and breathe in the fresh air! ### How do I find the best car hire deals in Murphysboro with Expedia? ### How old do you have to be to hire a car in Murphysboro? ### What do you need to rent a car in Murphysboro? ### What is the cheapest car hire in Murphysboro? ### Can I hire a car for a month or longer in Murphysboro? ### Where can I find a Murphysboro hire car if I am younger than 25? ### Can I drive in Murphysboro with my current driver's license? > - Age restrictions: You'll need to be 25 in many states in order to hire a car, although in some places the minimum age is 21\. We recommend checking local regulations, as well as with the hired car company before you travel to understand additional terms and conditions. > - Driving limitations: Don't forget to read the fine print before you leave the lot so you can avoid any unnecessary charges. When hiring a car in the United States, it's usually prohibited to cross country borders into Mexico or Canada, use car ferries or traverse certain types of rugged terrain with your hire car. We recommend reading all the rules and regulations before booking! ### Why should I rent a Murphysboro car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | £42 | | Our second best deal of the day: | £47 | | Our third best deal of the day: | £61 | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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