Title: Cheap Car Hire in Irvine Research Center, USA - Expedia.co.uk [Irvine Research Center Travel Guide](https://expedia.co.uk/Irvine-Irvine-Research-Center.dx553248635976470092)[Hotels in Irvine Research Center](https://expedia.co.uk/Irvine-Research-Center-Irvine-Hotels.0-n553248635976470092-0.Travel-Guide-Filter-Hotels)[Flights to Irvine](https://expedia.co.uk/Cheap-Flights-To-Irvine.d7819.Travel-Guide-Flights)[Things to do in Irvine](https://expedia.co.uk/Things-To-Do-In-Irvine.d7819.Travel-Guide-Activities)[Irvine Research Center Holidays](https://expedia.co.uk/Irvine-Research-Center.d553248635976470092.Holidays-City-Breaks) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Irvine Research Center, USA ## Search and Compare from Car Companies in Irvine Research Center ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Irvine Research Center \* Price found within the past 6 days. Click for updated prices. Tue, 31 Mar - Wed, 1 Apr ### Standard Chevrolet Cruze or similar - 5 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) #### Pick-up location 18601 Airport Way Suite 71, Santa Ana, California 92707, USA 8.08 mi from Irvine Research Center city centre ![Chevrolet Cruze](//mediaim.expedia.com/cars/43/428f5fd5-c16a-45ea-83fa-3c6a0e647b4c.jpg) #### £44 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675555&olon=-117.868330&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=44.23&cvrfrr=ZR&ctrfrr=SC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Tue, 31 Mar - Wed, 1 Apr ### Economy Chevrolet Spark or similar - 4 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) #### Pick-up location 18601 Airport Way Suite 71, Santa Ana, California 92707, USA 8.08 mi from Irvine Research Center city centre ![Chevrolet Spark](//mediaim.expedia.com/cars/43/b709c353-edf9-46a5-98da-f1197c7af6eb.jpg) #### £45 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675555&olon=-117.868330&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=45.32&cvrfrr=ZR&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Tue, 31 Mar - Wed, 1 Apr ### Full Size Chevrolet Malibu or similar - 5 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) #### Pick-up location 18601 Airport Way Suite 71, Santa Ana, California 92707, USA 8.08 mi from Irvine Research Center city centre ![Chevrolet Malibu](//mediaim.expedia.com/cars/43/b49ce8d5-44b1-4182-803e-eef770b10bb8.jpg) #### £46 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675555&olon=-117.868330&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=46.34&cvrfrr=ZR&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Tue, 31 Mar - Wed, 1 Apr ### Compact Nissan Versa Note or similar - 5 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) #### Pick-up location 18601 Airport Way Suite 71, Santa Ana, California 92707, USA 8.08 mi from Irvine Research Center city centre ![Nissan Versa Note](//mediaim.expedia.com/cars/43/79fd35f4-a9f4-405e-a7d7-3a501dfc88c1.jpg) #### £47 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675555&olon=-117.868330&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=46.67&cvrfrr=ZR&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Tue, 31 Mar - Wed, 1 Apr ### Midsize Toyota Corolla or similar - 5 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) #### Pick-up location 18601 Airport Way Suite 71, Santa Ana, California 92707, USA 8.08 mi from Irvine Research Center city centre ![Toyota Corolla](//mediaim.expedia.com/cars/43/66993783-7008-48ae-be5b-e0280e3a6f76.jpg) #### £47 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675555&olon=-117.868330&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=46.84&cvrfrr=ZR&ctrfrr=IC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Fri, 3 Apr - Sat, 4 Apr ### Special Managers Special or similar - 4 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) #### Pick-up location 18601 Airport Way Suite 71, Santa Ana, California 92707, USA 8.08 mi from Irvine Research Center city centre ![Managers Special](//mediaim.expedia.com/cars/43/eb66feb7-951f-4cc5-bc22-f50d5dc5457e.jpg) #### £53 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675555&olon=-117.868330&date1=03/04/2026&date2=04/04/2026&pprfrr=null&tprfrr=52.75&cvrfrr=ZR&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Tue, 31 Mar - Wed, 1 Apr ### Midsize Elite BMW 2 SERIES or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location John Wayne Airport Sna, 18601 Airport Way, Santa Ana, California 92707-5200, USA 8.08 mi from Irvine Research Center city centre ![BMW 2 SERIES](//mediaim.expedia.com/cars/35/f7ab4e1e-1373-4403-929f-c04959e7b3c8.jpg) #### £90 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675560&olon=-117.868300&date1=31/03/2026&date2=01/04/2026&pprfrr=80.78&tprfrr=89.52&cvrfrr=SX&ctrfrr=JC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Tue, 31 Mar - Wed, 1 Apr ### Full Size Elite BMW 3 SERIES or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location John Wayne Airport Sna, 18601 Airport Way, Santa Ana, California 92707-5200, USA 8.08 mi from Irvine Research Center city centre ![BMW 3 SERIES](//mediaim.expedia.com/cars/35/b31b7147-93f8-487d-a013-186a1dd7936c.jpg) #### £94 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.675560&olon=-117.868300&date1=31/03/2026&date2=01/04/2026&pprfrr=84.58&tprfrr=93.72&cvrfrr=SX&ctrfrr=GC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Fri, 3 Apr - Sat, 4 Apr ### Premium Pickup Regular Cab Ford F150 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) #### Pick-up location 19051 Airport Way North, Santa Ana, California 92707, USA 7.83 mi from Irvine Research Center city centre ![Ford F150](//mediaim.expedia.com/cars/6/b9f0687c-ec07-4124-8b53-27941227757b.jpg) #### £94 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.668087&olon=-117.866543&date1=03/04/2026&date2=04/04/2026&pprfrr=null&tprfrr=93.71&cvrfrr=AL&ctrfrr=PP&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22pickup%22]) Tue, 31 Mar - Wed, 1 Apr ### Standard Elite SUV Ford Explorer or similar - 7 people - Unlimited mileage ![Budget](//mediaim.expedia.com/cars/logos/ZD.png) #### Pick-up location John Wayne Orange County Airport - 18601 Airport Way, Ste 73, Santa Ana, California 92707-5204, USA 7.81 mi from Irvine Research Center city centre ![Ford Explorer](//mediaim.expedia.com/cars/39/0117d125-955b-455f-87f1-0c60b7d7c1bc.jpg) #### £100 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.666660&olon=-117.866700&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=99.74&cvrfrr=ZD&ctrfrr=RF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Tue, 31 Mar - Wed, 1 Apr ### Luxury Cadillac CT5 or similar - 5 people - Unlimited mileage ![Budget](//mediaim.expedia.com/cars/logos/ZD.png) #### Pick-up location John Wayne Orange County Airport - 18601 Airport Way, Ste 73, Santa Ana, California 92707-5204, USA 7.81 mi from Irvine Research Center city centre ![Cadillac CT5](//mediaim.expedia.com/cars/39/2bd5c014-4d39-4590-bba3-eb45924b7c90.jpg) #### £103 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.666660&olon=-117.866700&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=103.39&cvrfrr=ZD&ctrfrr=LC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Wed, 1 Apr - Thu, 2 Apr ### Mini Van Chrysler Pacifica or similar - 7 people - Unlimited mileage ![Budget](//mediaim.expedia.com/cars/logos/ZD.png) #### Pick-up location John Wayne Orange County Airport - 18601 Airport Way, Ste 73, Santa Ana, California 92707-5204, USA 7.81 mi from Irvine Research Center city centre ![Chrysler Pacifica](//mediaim.expedia.com/cars/39/e7400a6a-2473-474b-9d79-35076bd3a23f.jpg) #### £106 total found 20 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.666660&olon=-117.866700&date1=01/04/2026&date2=02/04/2026&pprfrr=null&tprfrr=105.64&cvrfrr=ZD&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) Fri, 3 Apr - Sat, 4 Apr ### Premium Elite Mercedes GLE BMW X5 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) #### Pick-up location 19051 Airport Way North, Santa Ana, California 92707, USA 7.83 mi from Irvine Research Center city centre ![Mercedes GLE BMW X5](//mediaim.expedia.com/cars/6/dcb7bd16-08f7-4b79-ac45-b858f31e4a46.jpg) #### £107 total found 2 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.668087&olon=-117.866543&date1=03/04/2026&date2=04/04/2026&pprfrr=null&tprfrr=107.22&cvrfrr=AL&ctrfrr=UD&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22premium%22]) ### Don't see what you're looking for? See all car hire in Irvine Research Center [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Irvine%20Research%20Center,%20Irvine,%20California,%20United%20States%20of%20America&dpln=553248635976470092&date1=05/04/2026&date2=07/04/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 20 hours. Prices and availability subject to change. Additional terms may apply. ## Frequently asked questions ### How much is a rental car per day in Irvine Research Centre? ### What happens if I need to cancel my Irvine Research Centre car reservation? ### What types of cars can I rent in Irvine Research Centre? ### How do I find the best car hire deals in Irvine Research Centre with Expedia? ### How old do you have to be to hire a car in Irvine Research Centre? ### What do you need to hire a car in Irvine Research Centre? ### What is the cheapest car hire in Irvine Research Centre? ### Can I hire a car for a month or longer in Irvine Research Centre? ### Where can I find an Irvine Research Centre hire car if I am younger than 25? ### Can I drive in Irvine Research Centre with my current driver's license? > - Age restrictions: You must be at least 25 in most states to be able to hire a car, although in some places the minimum age is 21\. We recommend checking local rules and regulations, and with the hire car company before you go to understand all the terms and conditions. > - Driving limitations: Read the fine print before you get behind the wheel so you can avoid any unnecessary fees. When hiring a car in the United States, it's usually prohibited to cross country borders into Mexico or Canada, use car ferries or traverse certain types of rugged terrain with your car hire. Please read the regulations before booking! ### Why should I rent an Irvine Research Centre car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | £44 | | Our second best deal of the day: | £45 | | Our third best deal of the day: | £46 | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) |