Title: Cheap Flights to La Serena - Expedia.co.uk ![Lighthouse at La Serena, Chile](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £27 Cheap Flights to La Serena [View £27 flight on Wed, 25 Mar 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:SCL,to:LSC,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:26.80&airProductToken=AQovCi0IyGQSBDE3MjAY0lggyxQo5MqIAzCry4gDOEFAAFgBagJaT3IIQVpPMTAwMDASCggBEAEYASoCSFIYASIECAEQASgCKAMoBDAB) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Hotels in La Serena](https://expedia.co.uk/La-Serena-Hotels.d2139.Travel-Guide-Hotels)[Things to do in La Serena](https://expedia.co.uk/Things-To-Do-In-La-Serena.d2139.Travel-Guide-Activities)[La Serena Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Serena.d2139.Car-Hire-Guide)[La Serena Holidays](https://expedia.co.uk/La-Serena.d2139.Holidays-City-Breaks) ## Popular airlines to La Serena - ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:La Serena, Coquimbo Region, Chile,departure:04/10/2025TANYT&leg2=from:La Serena, Coquimbo Region, Chile,to:CMH,departure:11/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![Sky Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_H2.svg) Sky Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:La Serena, Coquimbo Region, Chile,departure:04/10/2025TANYT&leg2=from:La Serena, Coquimbo Region, Chile,to:CMH,departure:11/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"H2"}}]) - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:La Serena, Coquimbo Region, Chile,departure:04/10/2025TANYT&leg2=from:La Serena, Coquimbo Region, Chile,to:CMH,departure:11/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) - ![B & H Airlines](https://a.travel-assets.com/air/airlines/ja.gif) B & H Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:La Serena, Coquimbo Region, Chile,departure:04/10/2025TANYT&leg2=from:La Serena, Coquimbo Region, Chile,to:CMH,departure:11/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"JA"}}]) - ![Qantas Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_QF.svg) Qantas Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:La Serena, Coquimbo Region, Chile,departure:04/10/2025TANYT&leg2=from:La Serena, Coquimbo Region, Chile,to:CMH,departure:11/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"QF"}}]) - ## Plan, book, fly with confidence - ### Be in the know Get alerts if flight prices drop or rise\* - ### Book smarter Save up to 25% on select hotels after you book a flight\* - ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to La Serena Prices were available within the past 7 days and start at £27 for one-way flights and £53 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![SKY AIRLINE](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/H2.gif) Sun, 15 Mar - Sun, 22 Mar SCL Santiago LSC La Serena £53 Return found 13 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:LSC,departure:15/03/2026TANYT&leg2=from:LSC,to:SCL,departure:22/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:52.60&airProductToken=AQovCi0IyGQSBDE3MTQY0lggyxQopNqHAzDr2ocDOEFAAFgBagJaT3IIQVpPMTAwMDAKLgosCMhkEgMyMDUYyxQg0lgo2KiIAzCYqYgDOEFAAFgBagJaT3IIQVpPMTAwMDASCggBEAEYASoCSFIYASIECAEQASgCKAMoBDAB) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Sun, 15 Mar - Sun, 22 Mar SCL Santiago LSC La Serena £54 Return found 13 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:LSC,departure:15/03/2026TANYT&leg2=from:LSC,to:SCL,departure:22/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:54.00&airProductToken=AQovCi0IzIIBEgMxMDQY0lggyxQo0NmHAzCV2ocDOEdAAFgBagJRUHIIRzAwUVA1WkoSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Sun, 15 Mar - Sun, 22 Mar SCL Santiago LSC La Serena £55 Return found 13 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:LSC,departure:15/03/2026TANYT&leg2=from:LSC,to:SCL,departure:22/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:54.40&airProductToken=AQovCi0IzIIBEgMxMDQY0lggyxQo0NmHAzCV2ocDOEdAAFgBagJRUHIIRzAwUVA1WkoKLwotCMyCARIDMTAzGMsUINJYKOCniAMwmaiIAzhHQABYAWoCUVByCEcwMFFQNVpKEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ) ![Turkish Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TK.gif) Fri, 10 Oct - Wed, 22 Oct MAN Manchester LSC La Serena £1,062 Return found 22 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:LSC,departure:10/10/2025TANYT&leg2=from:LSC,to:MAN,departure:22/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1061.76&airProductToken=AQpmCiEI1JYBEgQxOTE2GIxoIMicASi3gfoCMKyD-gI4TEAAWAEKIAjUlgESAzIxNRjInAEg0lgoiIr6AjCGk_oCOExAAVgBCh8IzIIBEgMxMDYY0lggyxQojJT6AjDQlPoCOE1AAVgBCmYKHwjMggESAzEwORjLFCDSWCi5ifsCMPCJ-wI4TkAAWAEKIAjUlgESAzIxNhjSWCDInAEo2Y_7AjCbmPsCOExAAVgBCiEI1JYBEgQxOTk1GMicASCMaCjPmfsCMMmb-wI4TEABWAESCggBEAEYASoCVEsYASIECAEQASgEMAE) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 9 Oct - Tue, 21 Oct MAN Manchester LSC La Serena £1,424 Return found 19 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:LSC,departure:09/10/2025TANYT&leg2=from:LSC,to:MAN,departure:21/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1423.06&airProductToken=AQplCiAIyYQBEgQxODkyGIxoIIwYKKf0-QIwvfX5AjhIQABYAQofCMmEARIDMTEzGIwYINJYKKj8-QIww4L6AjhIQAFYAQogCMmEARIENjU1NhjSWCDLFCivh_oCMPCH-gI4QUABWAEKZQogCMmEARIENjU1NRjLFCDSWCjs_foCMKP--gI4QUAAWAEKHwjJhAESAzExOBjSWCCMGCj_hPsCMPeK-wI4T0ABWAEKIAjJhAESBDE4OTEYjBggjGgoqZD7AjC_kfsCOE9AAVgBEgoIARABGAEqAklCGAEiBAgBEAEoBDAB) ## Frequently asked questions ### What is the name of La Serena's airport? > La Serena has just one airport, La Florida Airport (LSC). ### How far is La Serena La Florida Airport from central La Serena? > If you're basing yourself in the centre of La Serena, you'll be there within moments after touching down at La Serena La Florida Airport. The terminal is only 5 kms (3 miles) from the downtown area. ### What airport is best to fly into La Serena? > A flight to La Serena means landing at La Serena La Florida Airport. Get off the plane, grab your bags and you'll be 5 kms (3 miles) from the downtown area. ### How many airlines fly to La Serena? > With 3 air carriers jetting into La Serena from 6 airports around the globe, your next adventure is just a few clicks away. ### Which airlines fly to La Serena? > La Serena receives the largest number of flights from LATAM Airlines, Sky Airline and JetSmart with LATAM Airlines being the preferred choice of carrier. Santiago is the most popular city for passengers to take off from. ### How many nonstop flights are there to La Serena? > With approximately 135 nonstop flights every week, you'll be hitting the tarmac in La Serena before you can say, "Are we there yet?" ### Where are the most popular flights to La Serena departing from? > Flights to La Serena departing from Santiago, Calama and Antofagasta airports are in high demand. ### How long is the flight to La Serena Airport? > If you're heading to La Serena from Santiago, you're looking at a flight duration of 1 hour and 7 minutes. Those taking off from Calama can expect to be in the air for 1 hour and 39 minutes. From Antofagasta it's 1 hour and 24 minutes away. ### How to book the cheapest flight to La Serena? > Don't leave locking in your flight to La Serena until the last minute. That's one move frequent jet-setters use to get the best prices. Booking in advance means more options and less expensive flights. Another good way to grab the most affordable fare is to shop around. If where you're headed has a few airports, don't forget to look into the cost of flying into a less busy terminal. Last but not least, be ready to book quickly if you find a great price. It might not be available for too long. With a bit of know-how and some luck, the perfect airfare will be yours. ### Do you have any tips for my flight to La Serena? > We've got the lowdown on how to make your journey as pain-free as possible. Follow our tips and you'll be zooming through airport security and exploring La Serena in no time flat. What to pack in your hand luggage: > > > > - The trick to having a pain-free travel experience is to pack in advance. So, let's start with the basics: passport, travel documents, credit cards and important medications. Next, take on board items that'll help keep you entertained, like some electronic gadgets or a juicy novel. You'll also want to pack your chargers, a quality neck pillow and a pair of headphones. Last but not least, don't forget to pop in toiletries like a toothbrush, cleansing wipes and a fresh change of clothes. > > > > Do not pack the following items in your hand luggage: > > > > - Make sure you don't have a sharp object hiding in the bottom of your hand luggage. Other prohibited items include flammable or explosive products, such as aerosol cans and fuel, and gels and liquids in containers larger than 3.4 ounces (100 millilitres). > > > > What to wear on a flight: > > > > - Comfort should be your top priority when deciding what to wear on board. Loose, breathable clothing is a wise option, as are flat, slip-on shoes. > - Most travellers have heard about deep vein thrombosis (DVT), a blood clot condition caused by long periods of inactivity. To lower your risk on board, drink lots of water, consider wearing compression socks and move your lower limbs often. ### How to get through airport security fast when flying to La Serena? > The secret is to be prepared before you arrive at the airport security gate. That way, you'll be stepping onto that plane to La Serena in no time flat. Follow these helpful tips and get your holiday off to a great start: > > > > - Be sure to keep your travel documents and passport close by. They're the first items you'll be asked to show at security. > - The X-ray machine is up next. Remove anything on you that is likely to set off the alarm. This includes items like headphones or earphones, as well as your coat or jacket. They'll need to be placed on the conveyor belt for screening. > - All electronic gadgets, including your phone and tablet, are also required to be scanned separately. > - Any gels or liquids, such as perfume or hand cream, that you want to take on board need to be in containers no larger than 3.4 ounces (100 millilitres). They must also all fit inside a quart-size (one litre), zip-lock bag. > - There's a good chance you'll be asked to remove your shoes for scanning, so wearing lightweight sneakers is always a clever idea. > - Airlines will not allow any pocket knives or other sharp items to come on board with you. If you must bring these kinds of items, pack them safely in your checked luggage. ## Book with confidence ### Expedia flights to La Serena Searching for cheap flights to La Serena? No travel company presents more choices than Expedia if you're looking to compare flights to La Serena. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Coquimbo Region. Expedia provides the cheapest flights to many destinations in Coquimbo Region and you may find even greater savings if you combine your flight with a hotel stay in La Serena. Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast. Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to La Serena for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your La Serena flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price. ## Travel information | Destination airport | La Florida | | --- | --- | | Destination airport IATA code | LSC | | Destination city name | La Serena | | Return price | £53 | ## Trending flights to La Serena Prices were available within the past 7 days and start at £27 for one-way flights and £53 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Turkish Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TK.gif) Fri, 10 Oct - Wed, 22 Oct MAN Manchester LSC La Serena £1,062 Return found 22 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:LSC,departure:10/10/2025TANYT&leg2=from:LSC,to:MAN,departure:22/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1061.76&airProductToken=AQpmCiEI1JYBEgQxOTE2GIxoIMicASi3gfoCMKyD-gI4TEAAWAEKIAjUlgESAzIxNRjInAEg0lgoiIr6AjCGk_oCOExAAVgBCh8IzIIBEgMxMDYY0lggyxQojJT6AjDQlPoCOE1AAVgBCmYKHwjMggESAzEwORjLFCDSWCi5ifsCMPCJ-wI4TkAAWAEKIAjUlgESAzIxNhjSWCDInAEo2Y_7AjCbmPsCOExAAVgBCiEI1JYBEgQxOTk1GMicASCMaCjPmfsCMMmb-wI4TEABWAESCggBEAEYASoCVEsYASIECAEQASgEMAE) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [Alcoguaz Hotels](https://www.expedia.co.uk/Alcoguaz-Hotels.d3000006451.Travel-Guide-Hotels) - [Coquimbo Hotels](https://www.expedia.co.uk/Coquimbo-Hotels.d6024027.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Coquimbo Region](https://www.expedia.co.uk/Destinations-In-Coquimbo-Region-Gay-Friendly-Hotel.0-0-d6236544-tGayFriendlyHotel.Hotel-Filter-Destinations) - [Coquimbo Region Hotels](https://www.expedia.co.uk/Destinations-In-Coquimbo-Region.d6236544.Hotel-Destinations) - [Hotels near Elqui Valley](https://www.expedia.co.uk/Elqui-Valley-Hotels.0-l6293291-0.Travel-Guide-Filter-Hotels) - [Horcón Hotels](https://www.expedia.co.uk/Horcon-Hotels.d3000006399.Travel-Guide-Hotels) - [La Herradura Hotels](https://www.expedia.co.uk/La-Herradura-Hotels.d6293292.Travel-Guide-Hotels) - [La Higuera Hotels](https://www.expedia.co.uk/La-Higuera-Hotels.d6203805.Travel-Guide-Hotels) - [Hotels near La Silla Observatory](https://www.expedia.co.uk/La-Silla-Observatory-Hotels.0-l6098444-0.Travel-Guide-Filter-Hotels) - [Las Mollacas Hotels](https://www.expedia.co.uk/Las-Mollacas-Hotels.d553248635946399536.Travel-Guide-Hotels) - [Monte Grande Hotels](https://www.expedia.co.uk/Monte-Grande-Hotels.d3000470723.Travel-Guide-Hotels) - [Monte Patria Hotels](https://www.expedia.co.uk/Monte-Patria-Hotels.d6141337.Travel-Guide-Hotels) - [Ovalle Hotels](https://www.expedia.co.uk/Ovalle-Hotels.d6143185.Travel-Guide-Hotels) - [Pisco Elqui Hotels](https://www.expedia.co.uk/Pisco-Elqui-Hotels.d3000006314.Travel-Guide-Hotels) - [Punta de Choros Hotels](https://www.expedia.co.uk/Punta-De-Choros-Hotels.d6293308.Travel-Guide-Hotels) - [Rapel Hotels](https://www.expedia.co.uk/Rapel-Hotels.d3000384148.Travel-Guide-Hotels) - [Rio Hurtado Hotels](https://www.expedia.co.uk/Rio-Hurtado-Hotels.d6140331.Travel-Guide-Hotels) - [Totoralillo Hotels](https://www.expedia.co.uk/Totoralillo-Hotels.d6293298.Travel-Guide-Hotels) - [Vicuña Hotels](https://www.expedia.co.uk/Vicuna-Hotels.d6203808.Travel-Guide-Hotels) - [Flights to Coquimbo](https://www.expedia.co.uk/Cheap-Flights-To-Coquimbo.d6024027.Travel-Guide-Flights) - [Flights from La Florida](https://www.expedia.co.uk/lp/airports/lsc/flights-from-la-florida-airport) - [Flights from Paris (CDG) to La Serena (LSC)](https://www.expedia.co.uk/lp/flights/cdg/lsc/paris-to-la-serena) - [Flights from Calama (CJC) to La Serena (LSC)](https://www.expedia.co.uk/lp/flights/cjc/lsc/calama-to-la-serena) - [Flights from London (LHR) to La Serena (LSC)](https://www.expedia.co.uk/lp/flights/lhr/lsc/london-to-la-serena) - [Flights from Manchester (MAN) to La Serena (LSC)](https://www.expedia.co.uk/lp/flights/man/lsc/manchester-to-la-serena) - [Flights from Santiago (SCL) to La Serena (LSC)](https://www.expedia.co.uk/lp/flights/scl/lsc/santiago-to-la-serena) - [Cerro Tololo Observatory](https://www.expedia.co.uk/Cerro-Tololo-Observatory-Vicuna.d6098438.Attraction) - [Visit Coquimbo](https://www.expedia.co.uk/Coquimbo.dx6024027) - [Cruz del Tercer Milenio Monument](https://www.expedia.co.uk/Cruz-Del-Tercer-Milenio-Monument-Coquimbo.d6293445.Attraction) - [Kokoro No Niwa Japanese Garden](https://www.expedia.co.uk/Kokoro-No-Niwa-Japanese-Garden-La-Serena.d6098428.Attraction) - [Visit La Higuera](https://www.expedia.co.uk/La-Higuera.dx6203805) - [Visit Monte Patria](https://www.expedia.co.uk/Monte-Patria.dx6141337) - [Visit Ovalle](https://www.expedia.co.uk/Ovalle.dx6143185) - [Rental cars La Florida airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Florida.d6029785.Car-Hire-Guide) - [La Herradura Holiday Rentals](https://www.expedia.co.uk/La-Herradura-Holiday-Rentals.d6293292.Travel-Guide-HolidayRentals) \*Available to Expedia members.