Centro Histórico Holidays
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Top hotels in Centro Histórico
Hotel Las Américas
Calle 21 de Mayo esq, Seoane N 356 Santa Cruz Santa Cruz Department
Fully refundableReserve now, pay when you stay
£19
12 Sept - 13 Sept
7.8/10 Good! (28 reviews)
"DELICIOSO EL DESAYUNO"
Reviewed on 3 Sept 2026
Lido Hotel
Calle 21 de Mayo 527 Santa Cruz
£18
13 Sept - 14 Sept
Hotel Pascana centro
sucre 0 Santa Cruz Département de Santa Cruz
Fully refundableReserve now, pay when you stay
£38
14 Sept - 15 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Centro Histórico attractions
Plaza 24 de Septiembre
8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
San Lorenzo Cathedral
9.0/10 (84 reviews)
One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.
Arenal Park
7.4/10 (16 reviews)
After visiting Arenal Park, make a plan to see the other sights and activities in Santa Cruz. While in the area, you can find time to visit its shops.
Artecampo
8.8/10 (12 reviews)
During your trip to Santa Cruz, you can find the perfect gifts to bring home at Artecampo. Make some time to visit the cathedral while you're in the area.
Ethno-folkloric Museum
9.0/10 (16 reviews)
You can spend an afternoon exploring the galleries in Ethno-folkloric Museum in Santa Cruz. While in the area, you can find time to visit its shops.
La Recova Artisan Walk
8.8/10 (20 reviews)
During your trip to Santa Cruz, you can do some window-shopping at La Recova Artisan Walk. Make some time to visit the cathedral while you're in the area.
Franco Aleman Cultural Center
10.0/10 (1 review)
Enjoy an outing to Franco Aleman Cultural Center during your stay in Santa Cruz. While in the area, you can find time to visit its shops.
Sacred Art Museum
8.8/10 (10 reviews)
You can spend an afternoon browsing the exhibits at Sacred Art Museum in Santa Cruz. While in the area, you can find time to visit its shops.
Things to do
Santa Cruz and Porongo: History, Markets, River, and Culture
£73
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
£62
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
£231
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.