
Cayos Los Grullos Holidays from £968
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top Cayos Los Grullos Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.

Las Americas Golden Tower Panama
San Francisco
Price was £1,355, price is now £968 per person
£968
per person
17 Aug - 24 Aug
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9/10 Wonderful! (1,016 reviews)
The hotel was ok, clean and comfortable but when we booked it we saw they have a rooftop and when we asked they say it was only for events. Then we wanted to use the pool but it was indoors which it wasn’t mentioned on the website.
The best was the breakfast buffet.
Reviewed on 7 Jun 2026

Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was £2,060, price is now £1,102 per person
£1,102
per person
17 Aug - 24 Aug
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9.2/10 Wonderful! (1,004 reviews)
Our stay was great ! Definitely worth staying here 👍
Reviewed on 6 Jun 2026

Megapolis Hotel Panamá
San Francisco
Price was £1,667, price is now £1,039 per person
£1,039
per person
17 Aug - 24 Aug
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
8.4/10 Very Good! (1,543 reviews)
El bufet ay muy poco personal de trabajadores para prestar un buen servicio
Reviewed on 4 Jun 2026

Las Clementinas
Casco Viejo
Price was £1,581, price is now £1,139 per person
£1,139
per person
17 Aug - 24 Aug
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9.4/10 Exceptional! (189 reviews)
Best location. Beautiful heritage place and lovely restaurant attached.
Reviewed on 1 Jun 2026

Riande Aeropuerto Hotel & Casino
Price was £1,422, price is now £1,047 per person
£1,047
per person
17 Aug - 24 Aug
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
8.4/10 Very Good! (1,830 reviews)
Pool was and and everything was very clean and good food too. Everything has been improved from 3 years ago. Nice friendly staff. Two negatives, outdoor hot tub was colder than the pool, but pool was perfect. Outdoor bar, restaurant or no where could you charge anything to your room. Hard to to have cash when your at a swim up bar.
Reviewed on 26 May 2026
Top hotels in Cayos Los Grullos


San Blas Private Over-the-Water Cabin
Nusatupo Narganá Guna Yala
The price is £282 per night from 9 Jun to 10 Jun
£282
9 Jun - 10 Jun
includes taxes & fees
8/10 Very Good! (2 reviews)
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling ..."
Reviewed on 27 Oct 2022

Cabanas Narasgandub - Naranjo Chico
Kuna Yala Narganá Guna Yala
8/10 Very Good! (7 reviews)
Beautiful scenery and an amazing community
"Our stay at Cabanas Narasgandub was everything you would expect from a remote and rustic location. You will rise when the rooster crows at the crack of dawn and likely be sleepy shortly after the sun goes down. The cabins are extremely rustic and this location is not for someone expecting a 5 star ..."
Reviewed on 27 Sept 2019
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Cayos Los Grullos

All-Inclusive San Blas Islands Day Tour from Panama City
£112
per adult
100% of travellers recommend

San Blas Money Heist Island Day tour - 2-islands + Natural Pool
£50
per adult

San Blas Islands Day Trip – 3 Islands, Snorkel & Lunch
£51
per adult
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.










