Title: The Best Hotels Closest to Casa Santo Domingo Museum in Antigua Guatemala - 2026 Updated Prices | Expedia.co.uk [Casa Santo Domingo Museum Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Casa-Santo-Domingo-Museum.d553248621554184987.Car-Hire-Guide)[Casa Santo Domingo Museum Holidays](https://expedia.co.uk/Casa-Santo-Domingo-Museum-Barrio-De-La-Concepcion.d553248621554184987.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [30 Mar - 31 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621554184987&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [31 Mar - 1 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621554184987&startDate=2026-03-31&endDate=2026-04-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621554184987&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621554184987&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Casa Santo Domingo Museum hotels ![Comfort Suite, 1 King Bed | Terrace/patio](https://images.trvl-media.com/lodging/91000000/90770000/90762700/90762685/d33508a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/91000000/90770000/90762700/90762685/c2f67c0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/91000000/90770000/90762700/90762685/ce8223d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Villa | Minibar, individually decorated, individually furnished](https://images.trvl-media.com/lodging/91000000/90770000/90762700/90762685/87a4e1e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Las Mil Flores [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Villa-Las-Mil-Flores.h90762685.Hotel-Information) Historic Center, 0.2 mi from Casa Santo Domingo Museum 10/10 Exceptional (85 reviews) "the room is magical. the staff in flawlessly wonderful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) VICTOR £296 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Villa-Las-Mil-Flores.h90762685.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/18000000/17710000/17700300/17700242/1a7c39a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17710000/17700300/17700242/fcb602c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17710000/17700300/17700242/564fe1fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17710000/17700300/17700242/9ad18c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Aurora [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Aurora.h17700242.Hotel-Information) Historic Center, 0.1 mi from Casa Santo Domingo Museum 9.6/10 Exceptional (400 reviews) "The room was super clean, the staff was so nice. The breakfast was delicious and the hotel overall is in a great walking location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mileyshka £76 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Aurora.h17700242.Hotel-Information) ![43-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/ed7412a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/a8e41409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/w960h1279x0y0-f96be025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/16a2418d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luna Maya Boutique Hotel [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Luna-Maya-Boutique-Hotel.h110606649.Hotel-Information) 0.3 mi from Casa Santo Domingo Museum 9.6/10 Exceptional (46 reviews) "The staff were very helpful, the location was convenient for walking and the breakfast was delicious." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Rob £58 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Luna-Maya-Boutique-Hotel.h110606649.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/96000000/95550000/95543800/95543753/7adc4933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/96000000/95550000/95543800/95543753/08633270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95550000/95543800/95543753/ed42e88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95550000/95543800/95543753/5300626a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barbaras Boutique Hostel [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Barbaras-Boutique-Hostel.h95543753.Hotel-Information) 0.4 mi from Casa Santo Domingo Museum 10/10 Exceptional (28 reviews) "Clean room, super friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doylesa £93 includes taxes & fees 28 Apr - 29 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Barbaras-Boutique-Hostel.h95543753.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/d3874222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/4f38893b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/075994b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/0b1ab1c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Cruces Boutique Hotel [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Las-Cruces-Boutique-Hotel.h35287780.Hotel-Information) Historic Center, 0.3 mi from Casa Santo Domingo Museum 9.8/10 Exceptional (240 reviews) "Well situated, cozy, beautiful! I would stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maritza £230 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Las-Cruces-Boutique-Hotel.h35287780.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/3ddba04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Living area | 15-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/04c9e90c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | 1 bedroom, premium bedding, down duvets, Tempur-Pedic beds](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/c95674ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/b18ccd3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Santa Rosa Hotel Boutique [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Casa-Santa-Rosa-Hotel-Boutique.h3575304.Hotel-Information) Historic Center, 0.2 mi from Casa Santo Domingo Museum 9.6/10 Exceptional (353 reviews) "Great place to stay in a quieter part of Antigua but still within 10-15 min walk on the Central Park. Staff was amazingly attentive and morning breakfast was great. Would stay again anytime" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janna £144 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Casa-Santa-Rosa-Hotel-Boutique.h3575304.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/0a0a0571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/0c9b5ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 Suite Santa Rosa | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/1904b3c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/64e07485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Rafael Hotel [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-San-Rafael-Hotel.h6485588.Hotel-Information) Historic Center, 0.4 mi from Casa Santo Domingo Museum 9.8/10 Exceptional (455 reviews) "Beautiful hotel, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) benjamin £186 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-San-Rafael-Hotel.h6485588.Hotel-Information) ![Superior Room | Terrace/patio](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/a91bca25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/110dff66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/167a2963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/88032965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Noble Hotel [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Casa-Noble-Hotel.h74161287.Hotel-Information) 0.4 mi from Casa Santo Domingo Museum 9.6/10 Exceptional (193 reviews) "Very high class hotel room and the staff wete very kind. They were able to watch my luggage while i hiked the volcano despite not staying there the following night. And the complentary breakfast helped me prepare accordingly for the hike on the volcano. Would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis £100 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Casa-Noble-Hotel.h74161287.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/7c0f8307.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/c3660fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Jetted Tub (All rooms are different) | Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/b8f0936f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/b78e5b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Museo Spa Casa Santo Domingo [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) Barrio de La Concepción, < 0.1 mi from Casa Santo Domingo Museum 9.2/10 Wonderful (1,043 reviews) "Excellent hotel and museum " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dharti S £241 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/0aaf6a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch TV with cable channels](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/633b1a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/709e8c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/54d26564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Convento Boutique Hotel [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-El-Convento-Boutique-Hotel.h1836192.Hotel-Information) Historic Center, 0.3 mi from Casa Santo Domingo Museum 9.4/10 Exceptional (848 reviews) "BEAUTIFUL hotel and such a convenient location 100% recommend and WILL come back again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sabrina £214 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-El-Convento-Boutique-Hotel.h1836192.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/e88ac778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/6a239fb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/17346378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/2c45bacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Camino Real Antigua [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information) Historic Center, 0.6 mi from Casa Santo Domingo Museum 9.6/10 Exceptional (1,009 reviews) "Excellent hotel, highly recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa £166 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/cf0309b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/afaa82e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/cb7e866e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/b69a6270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posada de Don Rodrigo Antigua [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information) Historic Center, 0.4 mi from Casa Santo Domingo Museum 9.4/10 Exceptional (708 reviews) "Clean rooms, great location and friendly staff! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee £161 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/19000000/18720000/18719400/18719384/9ff645d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Private spa tub](https://images.trvl-media.com/lodging/19000000/18720000/18719400/18719384/6df44ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch Smart TV with cable channels, TV](https://images.trvl-media.com/lodging/19000000/18720000/18719400/18719384/fce74027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/19000000/18720000/18719400/18719384/29793e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Bella [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Casa-Bella.h18719384.Hotel-Information) Historic Center, 0.3 mi from Casa Santo Domingo Museum 9.4/10 Exceptional (305 reviews) "We enjoyed our stay immensely - the staff was so kind and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £69 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Casa-Bella.h18719384.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39210000/39204900/39204826/b90d36fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/40000000/39210000/39204900/39204826/8b8de649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39210000/39204900/39204826/a319859d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39210000/39204900/39204826/9bcc30e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ojala [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Ojala.h39204826.Hotel-Information) Historic Center, 0.6 mi from Casa Santo Domingo Museum 9.4/10 Exceptional (26 reviews) "Fantastic stay, central to everything, would highly recommend" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Peter £63 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Ojala.h39204826.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/5c4ec9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/dc7a83af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![64-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/f751d365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![64-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/8ccf1f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Bansley [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Casa-Bansley.h100442451.Hotel-Information) 0.8 mi from Casa Santo Domingo Museum 9.8/10 Exceptional (51 reviews) "Property is beautiful and staff are great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £82 includes taxes & fees 28 Apr - 29 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Casa-Bansley.h100442451.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/57bcd3b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/35eddbd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/014bd4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/b71b335d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Pasos Boutique Hotel & Spa [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Los-Pasos.h3856168.Hotel-Information) 0.5 mi from Casa Santo Domingo Museum 9.4/10 Exceptional (1,001 reviews) "Staff was super attentive. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Guisela Beatriz £149 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Los-Pasos.h3856168.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/da5ce8e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/da78e946.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/a0e98dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor wedding](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/e102ab87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Porta Hotel Antigua [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information) 0.5 mi from Casa Santo Domingo Museum 9.4/10 Exceptional (1,003 reviews) "Can't go wrong with this hotel, staff is great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gabriel £188 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/5b698a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/24d2ee6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/4fe76cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Fireplace, Mountain View | Living area | Smart TV](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/40ede138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posada del Angel [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Posada-Del-Angel.h3333323.Hotel-Information) 0.6 mi from Casa Santo Domingo Museum 9.6/10 Exceptional (286 reviews) "We had a great stay! The hotel is a very charming boutique hotel nestled in Antigua. The room was very comfortable and we were able to rest very well. The staff was always very helpful and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janelle £237 includes taxes & fees 21 Apr - 22 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Posada-Del-Angel.h3333323.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/16000000/15600000/15594300/15594252/28791a79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/16000000/15600000/15594300/15594252/295701ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/16000000/15600000/15594300/15594252/0ce017cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/16000000/15600000/15594300/15594252/1f970eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Good Hotel Antigua Guatemala, a Member of Design Hotels [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Good-Hotel-Antigua.h15594252.Hotel-Information) 0.2 mi from Casa Santo Domingo Museum 9.2/10 Wonderful (546 reviews) "Great modern simplistic hotel Definitely would stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara £163 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Good-Hotel-Antigua.h15594252.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/ea2518af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/18cfc72e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with cable channels, TV, fireplace](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/bf2eb57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, Select Comfort beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/0bd349dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### All Suite El Marques de Antigua [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-All-Suite-El-Marques-De-Antigua.h4359747.Hotel-Information) 0.6 mi from Casa Santo Domingo Museum 9.4/10 Exceptional (345 reviews) "LOVED this stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Giselle £79 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-All-Suite-El-Marques-De-Antigua.h4359747.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14®ionId=553248621554184987&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Casa Santo Domingo Museum | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Comfort Suite, 1 King Bed \| Terrace/patio](https://images.trvl-media.com/lodging/91000000/90770000/90762700/90762685/d33508a4.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Villa Las Mil Flores | 4.0 star property | 10.0Exceptional85 reviews | View | | | | | | | ![Garden](https://images.trvl-media.com/lodging/18000000/17710000/17700300/17700242/1a7c39a0.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Aurora | 3.5 star property | 9.6Exceptional400 reviews | View | | | | | | | ![43-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/ed7412a3.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Luna Maya Boutique Hotel | 3.0 star property | 9.6Exceptional46 reviews | View | | | | | | | ![Living area](https://images.trvl-media.com/lodging/96000000/95550000/95543800/95543753/7adc4933.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Barbaras Boutique Hostel | 2.0 star property | 10.0Exceptional28 reviews | View | | | | | | | ![Rooftop terrace](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/d3874222.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Las Cruces Boutique Hotel | 4.0 star property | 9.8Exceptional240 reviews | View | | | | | | ## Top Casa Santo Domingo Museum Hotel Reviews ![El Carmen Hotel](https://images.trvl-media.com/lodging/2000000/1220000/1211500/1211421/959d04eb_y.jpg) ### El Carmen Hotel 10/10 Excellent "Breakfast menu was delicious and included with stay! We were even able to place our orders the night before so our breakfasts would be ready when we got there! The A/C works magnificently. The grounds are immaculate and gorgeous. The staff could not be any kinder or more helpful. Transport to the airport (two different shuttles at two different times) were easily arranged and paid for online, and the vehicles and drivers were fabulous. I bring a veterinary team here twice a year, and I will never stay anywhere else. " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-El-Carmen-Hotel.h1211421.Hotel-Information) ![Hotel Camino Real Antigua](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/e88ac778_y.jpg) ### Hotel Camino Real Antigua 10/10 Excellent "The staff's attention is always excellent; they are very attentive to our needs. This Lenten and Holy Week season is unique because of the hotel's activities." [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information) ![Hotel Soleil La Antigua](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/a514483d_y.jpg) ### Hotel Soleil La Antigua 6/10 Okay "The food was basic, not many options to choose. " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Soleil-La-Antigua.h1517336.Hotel-Information) ![Hotel Convento Santa Catalina](https://images.trvl-media.com/lodging/11000000/10070000/10062000/10061913/5c7e4eb5_y.jpg) ### Hotel Convento Santa Catalina 8/10 Good "Under the Arch, Within the City Set beneath Antigua’s iconic arch, Hotel Convento Santa Catalina places you exactly where the city begins to breathe. Step outside and everything is near. Step inside and it softens—gardens, quiet corners, a pause from the street. Rooms are simple, spacious, and comfortable. The staff moves with quiet efficiency, arranging what you need before you ask—like our transfer to Lake Atitlán, handled with ease. In the days before Semana Santa, the city hums a little longer. By ten, it begins to fade; and sometimes, in the quiet hours, distant bells would wake us—we’d count the rings, then slip back into sleep. A stay defined not by excess, but by balance—location, calm, and the feeling of being exactly where you should be." [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Convento-Santa-Catalina.h10061913.Hotel-Information) ![Hotel Monasterio](https://images.trvl-media.com/lodging/11000000/10020000/10012000/10011905/ddcfa3f5_y.jpg) ### Hotel Monasterio 10/10 Excellent "Super limpio y bonito hotel!!! Muy amables y serviciales la gente que atiende en el hotel!!! Camas sábanas toallas Super limpio!!! Muy lindas habitaciones decoradas La comida y bebidas muy rico!! No hay ruido en ese hotel y muy bien ubicado" [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Monasterio.h10011905.Hotel-Information) ![Hotel Museo Spa Casa Santo Domingo](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/7c0f8307_y.jpg) ### Hotel Museo Spa Casa Santo Domingo 10/10 Excellent "It was an amazing experience ." [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) ![Porta Hotel Antigua](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/da5ce8e0_y.jpg) ### Porta Hotel Antigua 6/10 Okay "Room was okay, the place is beautiful; Antigua is magical and the hotel is nice and beautiful everywhere you go. The issue is service needs work. I was asked to leave my ID for a lent umbrella, leaving me with no ID in case police stops me, I’m paying well over two hundred per night and they don’t trust me with my umbrella? Could ask me to leave my room key so I don’t forget the umbrella or even make me sign a “loose it and pay for it ticket” ; but requiring me leave my ID was a discomfort. I think the staff is polite, but need some service training, I asked for tips on restaurants, favorite ruins within the city to visit, areas to walk to; all with multiple staff members and answers were always lukewarm “it’s all good” “anywhere is fine. " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information) ![El Convento Boutique Hotel](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/0aaf6a01_y.jpg) ### El Convento Boutique Hotel 10/10 Excellent "My favorite place in Guatemala!! So amazing " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-El-Convento-Boutique-Hotel.h1836192.Hotel-Information) ![Hotel Casa Antigua](https://images.trvl-media.com/lodging/4000000/3250000/3246100/3246073/af80dd45_y.jpg) ### Hotel Casa Antigua 8/10 Good "The hotel is in a great location to walk all over Antigua. The property has beautiful courtyards and gardens. The staff was friendly and helpful. The shower didn’t have hot water the first night but it got fixed quickly and was fine the rest of the time. " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Casa-Antigua.h3246073.Hotel-Information) ## Hotels near other Casa Santo Domingo Museum attractions ### Iglesia y Convento de Santo Domingo After visiting Iglesia y Convento de Santo Domingo, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops or seek out its local tours. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532965447) ### Jade Maya Factory and Museum 4.5/5 (188 reviews) During your trip to Antigua Guatemala, you can do some window-shopping at Jade Maya Factory and Museum. Discover the volcano viewpoints in this family-friendly area or enjoy its local tours. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532963887) ### Las Capuchinas Convent You can find out about the history of Antigua Guatemala with a trip to Las Capuchinas Convent. Discover the volcano viewpoints and shops in this romantic area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532619477) ### Antigua Tabaco Compania S.A. You can browse the exhibits at Antigua Tabaco Compania S.A., a museum with a story of its own, during your trip to Antigua Guatemala. Discover the area's volcano viewpoints or seek out its local tours. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532619476) ### Choco Museum You can browse the exhibits at Choco Museum, a museum with a story of its own, during your travels to Antigua Guatemala. Make time for the shops and local tours in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532619482) ### House of the Giants 5.0/5 (3 reviews) Take the family on an outing to House of the Giants during your trip to Antigua Guatemala. Discover the volcano viewpoints and shops in this romantic area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621554185019) ### Santa Clara Convent You can find out about the history of Antigua Guatemala with a visit to Santa Clara Convent. Discover the volcano viewpoints in this romantic area or enjoy its local tours. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532619469) ### Church of San Francisco 5.0/5 (2 reviews) After visiting Church of San Francisco, make a plan to see the other sights and activities in Antigua Guatemala. Discover the volcano viewpoints and shops in this romantic area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532965437) ## Frequently asked questions ### What's the area like around Casa Santo Domingo Museum? ### What's the best hotel to stay close to Casa Santo Domingo Museum? ### How many hotels are there near Casa Santo Domingo Museum? ### If I need to cancel the hotel reservation for my stay near Casa Santo Domingo Museum, will I receive a refund? ### What can I see and do near Casa Santo Domingo Museum?