Beginning of main content

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Trending Hotels Near Buffalo Museum of Science

See all 138 Hotels near Buffalo Museum of Science

Get 200 Nectar points when you book your hotel

Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.

Curtiss Hotel, An Ascend Hotel Collection Member

Curtiss Hotel, An Ascend Hotel Collection Member

210 Franklin St, Buffalo
5.0 out of 5.0
Last booking: 3 hours ago
11 others viewing this property now
4.8 out of 5 (79 reviews)

Located in Downtown Buffalo, this hotel is within a 10-minute walk of Shea's Performing Arts Center and Guaranty / Prudential Building. Coca-Cola Field and Canalside ...

£101

£101
Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown

10 Lafayette Square, Buffalo
3.0 out of 5.0
Last booking: 10 hours ago
1 others viewing this property now
4.4 out of 5 (357 reviews)

Located in Downtown Buffalo, this hotel is within a 10-minute walk of Lafayette Square and Coca-Cola Field. Pierce - Arrow Museum and Buffalo and Erie County ...

£75

£75
Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

220 Delaware Ave, Buffalo
3.0 out of 5.0
Last booking: 21 hours ago
2 others viewing this property now
4.6 out of 5 (852 reviews)

Located in Chippewa District, this hotel is within 1 mile (2 km) of Fountain Plaza, Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site and ...

£88

£88
Adam's Mark Buffalo

Adam's Mark Buffalo

120 Church St, Buffalo
3.0 out of 5.0
Last booking: 1 hour ago
10 others viewing this property now
3.4 out of 5 (2,798 reviews)

Located in Downtown Buffalo, this hotel is within a 10-minute walk of Niagara Square and Coca-Cola Field. Buffalo and Erie County Naval and Military Park and ...

£39

£39
DoubleTree Club by Hilton Buffalo Downtown

DoubleTree Club by Hilton Buffalo Downtown

125 High St, Buffalo
3.5 out of 5.0
Last booking: 3 days ago
1 others viewing this property now
4.3 out of 5 (760 reviews)

This family-friendly Buffalo hotel is located in the business district, within a 15-minute walk of Buffalo General Medical Center and Wilcox Mansion - Theodore ...

£80

£80
Millennium Buffalo

Millennium Buffalo

2040 Walden Ave, Cheektowaga
4.0 out of 5.0
Last booking: 39 minutes ago
2 others viewing this property now
4.1 out of 5 (649 reviews)

Situated near the airport, this hotel is within 1 mile (2 km) of Walden Galleria Mall and Holiday Twin Rinks. Buffalo Museum of Science and Stiglmeier Park are ...

£64

£64
Hotel Henry Urban Resort

Hotel Henry Urban Resort

444 Forest Avenue, Buffalo
4.0 out of 5.0
Last booking: 20 hours ago
3 others viewing this property now
4.2 out of 5 (49 reviews)

Situated in Buffalo, this hotel is within a 10-minute walk of Buffalo State College and Albright - Knox Art Gallery. Kleinhans Music Hall and Buffalo Zoo are ...

£99

£99
The Mansion On Delaware Ave

The Mansion On Delaware Ave

414 Delaware Ave, Buffalo
4.5 out of 5.0
Last booking: 1 day ago
4 others viewing this property now
4.6 out of 5 (205 reviews)

Located in Allentown, this hotel is within a 10-minute walk of Trinity Episcopal Church and Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site. ...

£150

£150
Hampton Inn Buffalo-Airport / Galleria Mall

Hampton Inn Buffalo-Airport / Galleria Mall

1745 Walden Ave, Cheektowaga
3.0 out of 5.0
Last booking: 1 hour ago
4.4 out of 5 (760 reviews)

Situated near the airport, in Cheektowaga, this hotel is close to Walden Galleria Mall, Holiday Twin Rinks and Iron Island Museum. Local attractions also include ...

£75

£75
Wyndham Garden Buffalo Williamsville

Wyndham Garden Buffalo Williamsville

5195 Main Street, Williamsville
4.0 out of 5.0
Last booking: 11 hours ago
3 others viewing this property now
4.7 out of 5 (744 reviews)

Situated near the airport, this spa hotel is within 1 mile (2 km) of Island Park and Glen Falls. Daemen College and Grover Cleveland Golf Course are also within ...

£84

£84