Photo by Cindy Keese
All hotels in Seneca, South Carolina
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
All hotels in Seneca, South Carolina
We have found 1588 Seneca, South Carolina hotels
- Lakeside Lodge Clemson
- Hampton Inn & Suites Seneca-Clemson Area
- Tru by Hilton Seneca Clemson
- Best Western Seneca-Clemson
- Tucker Farm Cottage on Century Farm
- Enchanting Historical1906 Modern Farmhouse: Perfect Blend of History and Comfort
- The Shepherd Hotel Downtown Clemson
- Best Western Plus Clemson Hotel & Conference Center
- Horizon Inn & Suites
- Inn @ Clemson
- Microtel Inn & Suites by Wyndham Anderson/Clemson
- Clemson University's James F. Martin Inn
- The Inn at Patrick Square
- The Abernathy of Clemson
- Hilton Garden Inn Anderson
- Home2 Suites by Hilton Anderson Downtown
- Hampton Inn Clemson-University Area
- Hampton Inn Hartwell
- Quality Inn
- Country Inn & Suites by Radisson, Anderson, SC
- Quality Inn
- Hampton Inn & Suites Lavonia
- BEAUTIFUL Newly Built Retreat w/Private Marina Boat Slip at Upper Lake Keowee!!!
- Hampton Inn Anderson
- Days Inn by Wyndham Lavonia
- Holiday Inn Express Hotel & Suites Lavonia by IHG
- Budget Inn Express
- Jewel of the Woods - Magnificent Views from an Incredible Lodge!
- Econo Lodge
- Americas Best Value Inn Anderson, SC
- Days Inn by Wyndham Royston
- Hartwell Suites
- The Bleckley Inn
- Liberty Hall Bed and Breakfast
- Windy Hill Lodge, A LUXURIOUS ESTATE
- Horse Cove Haven, Charming, Woodsy Retreat
- Moments Happen Here: 10 acres
- Country Hearth Inn & Suites Toccoa
Let Expedia take you to the best Hotels in Seneca. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.