Title: List of all Properties in Orangeburg | Expedia.co.uk ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/6058108/7d590932-d0d2-48e4-90bf-23f9acc0734e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # All hotels in Orangeburg, South Carolina - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide # All hotels in Orangeburg, South Carolina ### We have found 256 Orangeburg, South Carolina hotels > - [Travelodge by Wyndham Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) > - [SpringHill Suites by Marriott Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) > - [Spark by Hilton Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) > - [Fairfield Inn by Marriott Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) > - [Comfort Inn & Suites Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) > - [Baymont by Wyndham Orangeburg North ](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) > - [Hampton Inn & Suites Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) > - [Super 8 by Wyndham, Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) > - [Holiday Inn Express & Suites Orangeburg by IHG ](https://expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) > - [Quality Inn & Suites Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) > - [Sleep Inn Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) > - [Days Inn by Wyndham Orangeburg South ](https://expedia.co.uk/Orangeburg-Hotels-Days-Inn-By-Wyndham-Orangeburg-South.h3156.Hotel-Information) > - [Orangeburg Inn & Suites ](https://expedia.co.uk/Orangeburg-Hotels-Orangeburg-Inn-Suites.h105693778.Hotel-Information) > - [Suburban Studios Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Suburban-Studios.h102450856.Hotel-Information) > - [Southern Lodge & Suites ](https://expedia.co.uk/Orangeburg-Hotels-Southern-Lodge-Suites.h16006797.Hotel-Information) > - [Crown Inn By Oyo Orangeburg Hwy 301 ](https://expedia.co.uk/Orangeburg-Hotels-Crown-Inn-By-Oyo-Orangeburg-Hwy-301.h112646069.Hotel-Information) > - [Southern Lodge 601 ](https://expedia.co.uk/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information) > - [American INN of Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-American-INN-Of-Orangeburg.h856059.Hotel-Information) > - [Tru By Hilton Santee ](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) > - [Baymont by Wyndham Santee ](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) > - [Fairfield Inn & Suites by Marriott Santee ](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) > - [Hampton Inn Santee-I-95 ](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) > - [Best Western Plus Santee Inn ](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) > - [Holiday Inn Santee by IHG ](https://expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) > - [Peach Tree Inn ](https://expedia.co.uk/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) > - [Comfort Inn & Suites Santee ](https://expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) > - [Days Inn by Wyndham St George ](https://expedia.co.uk/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) > - [Travelodge by Wyndham Santee ](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) > - [Quality Inn & Suites ](https://expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) > - [Budget Inn By Belvilla St George I-95 ](https://expedia.co.uk/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) > - [Ramada by Wyndham Santee I-95 ](https://expedia.co.uk/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) > - [Red Roof Inn St George, SC ](https://expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) > - [Motel 6 Saint George, SC – I-95 ](https://expedia.co.uk/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) > - [Econo Lodge St. George ](https://expedia.co.uk/St-George-Hotels-Econo-Lodge-St-George.h889204.Hotel-Information) > - [Super 8 by Wyndham Santee ](https://expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) > - [Red Roof Inn Santee ](https://expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) > - [Econo Lodge ](https://expedia.co.uk/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) > - [Waterfront Condo on Lake Marion ](https://expedia.co.uk/Santee-Hotels-Spacious-Condo-On-Beautiful-Lake-Marion.h102018216.Hotel-Information) > - [Relax Inn ](https://expedia.co.uk/Orangeburg-Hotels-Relax-Inn.h48419847.Hotel-Information) > - [Quality Inn St George I-95 ](https://expedia.co.uk/St-George-Hotels-Quality-Inn-St-George-I-95.h4276.Hotel-Information) > - [Americas Best Value Inn St. George, SC ](https://expedia.co.uk/St-George-Hotels-Americas-Best-Value-Inn-St-George.h1058894.Hotel-Information) > - [3Bed/3Bath Deluxe at Lake Marion! ](https://expedia.co.uk/Santee-Hotels-3Bed3Bath-Deluxe-At-Lake-Marion.h108963171.Hotel-Information) > - [2Bed/2Bath Deluxe at Lake Marion! ](https://expedia.co.uk/Santee-Hotels-2Bed2Bath-Deluxe-At-Lake-Marion.h108962490.Hotel-Information) > - [Lake Marion 2Bed/2Bath Deluxe! ](https://expedia.co.uk/Santee-Hotels-Lake-Marion-2Bed2Bath-Deluxe.h108963596.Hotel-Information) > - [Lake Marion 3Bed/3Bath Deluxe! ](https://expedia.co.uk/Santee-Hotels-Lake-Marion-3Bed3Bath-Deluxe.h108964119.Hotel-Information) > - [AIKEN HISTORIC FARMHOUSE w Stables, Turnout 20 min to TOWN. ](https://expedia.co.uk/Salley-Hotels-AIKEN-HISTORIC-FARMHOUSE-W-Stables.h122722834.Hotel-Information) Let Expedia take you to the best Hotels in Orangeburg. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.