Compare and book 5 Star hotels in Southern Indiana, United States of America

    price find illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Southern Indiana 5 Star Hotels

Tonight
5 Jul - 6 Jul
Tomorrow
6 Jul - 7 Jul
Next weekend
11 Jul - 13 Jul
In two weeks
18 Jul - 20 Jul

Top Southern Indiana 5 Star Hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southern Indiana.
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY
The price is £114 per night from 7 Jul to 8 Jul
£114
7 Jul - 8 Jul
includes taxes & fees
8.8/10 Excellent! (3,413 reviews)
Still don't see what you're looking for?
See all properties in Southern Indiana.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

See all hotels in Southern Indiana
Kentucky Center for the Performing Arts which includes modern architecture

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Southern Indiana?
You'll find a range of pricing options for 5-star hotels in Southern Indiana on Expedia. How much you'll pay will depend on your travel dates, length of stay and other factors. Compare all of the available accommodation for your desired dates and make use of our pricing and other filters to score the perfect luxury stay.

  • Search for the lowest price per night from £114

What makes a hotel 5 stars in Southern Indiana?
Exemplary guest service is at the heart of every 5-star hotel in Southern Indiana. From the instant you arrive, staff cater to your every whim, whether arranging valet parking or providing in-room massage treatments. Also, hotels have to offer superior amenities to be entitled to a 5-star rating. These can include deluxe baths, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Southern Indiana?
Find an indulgent getaway that includes your lodging, meals, drinks and entertainment in Southern Indiana with Expedia's filter tool. Search for properties rated 5 stars and select the "All inclusive" filter. Be sure to check what's included in the price. That way, you can take full advantage of all the premium perks as soon as you arrive.