Title: The 10 Best 5 Star Hotels in Southern Indiana - 2025 Updated Prices | Expedia.co.uk

  

[Southern Indiana Travel Guide](https://expedia.co.uk/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Holiday Rentals in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Holiday-Rentals.d6059635.Travel-Guide-HolidayRentals)[Flights to Southern Indiana](https://expedia.co.uk/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Things to do in Southern Indiana](https://expedia.co.uk/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities)[Southern Indiana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Indiana.d6059635.Car-Hire-Guide)[Southern Indiana Holidays](https://expedia.co.uk/Southern-Indiana.d6059635.Holidays-City-Breaks)

![Kentucky Center for the Performing Arts which includes modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297198-Kentucky.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Compare and book 5 Star hotels in Southern Indiana, United States of America

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## Check availability on Southern Indiana 5 Star Hotels

Tonight

[16 Oct - 17 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2025-10-16&endDate=2025-10-17&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[17 Oct - 18 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2025-10-17&endDate=2025-10-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Southern Indiana 5 Star Hotels

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southern Indiana.

![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY

£120

1 Nov - 2 Nov

includes taxes & fees

8.8/10 Excellent! (3,671 reviews)

[](https://expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Omni Louisville Hotel](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Omni Louisville Hotel

400 S. 2nd Street, Louisville, KY

£175

1 Nov - 2 Nov

includes taxes & fees

9.2/10 Wonderful! (1,644 reviews)

[](https://expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![Embassy Suites Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY

£122

9 Nov - 10 Nov

includes taxes & fees

8.8/10 Excellent! (1,026 reviews)

[](https://expedia.co.uk/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Southern Indiana.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025&regionId=6059635&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025&regionId=6059635&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025&regionId=6059635&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025&regionId=6059635&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025&regionId=6059635&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025&regionId=6059635&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

[See all hotels in Southern Indiana](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31&adults=2&regionId=6059635)

![Kentucky Center for the Performing Arts which includes modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297198-Kentucky.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Southern Indiana Hotel Reviews

## Find out more about Southern Indiana

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Southern Indiana?

> You'll find a range of pricing options for 5-star hotels in Southern Indiana on Expedia. How much you'll pay will depend on your travel dates, length of stay and other factors. Compare all of the available accommodation for your desired dates and make use of our pricing and other filters to score the perfect luxury stay.
> 
>   
> 
> -   Search for the lowest price per night from £120

### What makes a hotel 5 stars in Southern Indiana?

> Exemplary guest service is at the heart of every 5-star hotel in Southern Indiana. From the instant you arrive, staff cater to your every whim, whether arranging valet parking or providing in-room massage treatments. Also, hotels have to offer superior amenities to be entitled to a 5-star rating. These can include deluxe baths, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.

### Are there any 5-star all-inclusive resorts in Southern Indiana?

> Find an indulgent getaway that includes your lodging, meals, drinks and entertainment in Southern Indiana with Expedia's filter tool. Search for properties rated 5 stars and select the "All inclusive" filter. Be sure to check what's included in the price. That way, you can take full advantage of all the premium perks as soon as you arrive.

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