Title: The 10 Best 5 Star Hotels in Mosel Wine Region - 2025 Updated Prices | Expedia.co.uk [Mosel Wine Region Travel Guide](https://expedia.co.uk/Mosel-Wine-Region.dx553248621593537217)[Hotels in Mosel Wine Region](https://expedia.co.uk/Mosel-Wine-Region-Hotels.d553248621593537217.Travel-Guide-Hotels)[Holiday Rentals in Mosel Wine Region](https://expedia.co.uk/Mosel-Wine-Region-Holiday-Rentals.d553248621593537217.Travel-Guide-HolidayRentals)[Flights to Mosel Wine Region](https://expedia.co.uk/Cheap-Flights-To-Mosel-Wine-Region.d553248621593537217.Travel-Guide-Flights)[Mosel Wine Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mosel-Wine-Region.d553248621593537217.Car-Hire-Guide)[Mosel Wine Region Holidays](https://expedia.co.uk/Mosel-Wine-Region.d553248621593537217.Holidays-City-Breaks) ![Stolzenfels Castle](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/222000/222005-Stolzenfels-Castle.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Mosel Wine Region, Rhineland-Palatinate ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mosel Wine Region 5 Star Hotels Tonight [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593537217&startDate=2025-10-11&endDate=2025-10-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593537217&startDate=2025-10-12&endDate=2025-10-13&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593537217&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593537217&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mosel Wine Region 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mosel-Wine-Region-Hotels.s50-0-d553248621593537217.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mosel-Wine-Region-Hotels.s50-0-d553248621593537217.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mosel Wine Region. ![Mercure Hotel Koblenz](https://images.trvl-media.com/lodging/1000000/30000/26000/25998/2ede69f4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Mercure Hotel Koblenz Julius-Wegeler-Strasse 6, Koblenz, RP £101 2 Nov - 3 Nov includes taxes & fees 8.2/10 Very Good! (1,000 reviews) [](https://expedia.co.uk/Koblenz-Hotels-Mercure-Hotel-Koblenz.h25998.Hotel-Information) ![FourSide Plaza Hotel Trier, Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/90000/82200/82136/0f7eea58_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### FourSide Plaza Hotel Trier, Trademark Collection by Wyndham Zurmaiener Straße 164, Trier, RP £63 9 Nov - 10 Nov includes taxes & fees 8.4/10 Very Good! (1,000 reviews) [](https://expedia.co.uk/Trier-Hotels-FourSide-Plaza-Hotel-Trier.h82136.Hotel-Information) ![Mercure Hotel Trier Porta Nigra](https://images.trvl-media.com/lodging/1000000/20000/19000/18934/ebe29f80_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Mercure Hotel Trier Porta Nigra Porta-Nigra-Platz 1, Trier, RP £64 2 Nov - 3 Nov includes taxes & fees 8.6/10 Excellent! (1,001 reviews) [](https://expedia.co.uk/Trier-Hotels-Mercure-Hotel-Trier-Porta-Nigra.h18934.Hotel-Information) Still don't see what you're looking for? [See all properties in Mosel Wine Region.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=11%2F10%2F2025&endDate=12%2F10%2F2025®ionId=553248621593537217&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=11%2F10%2F2025&endDate=12%2F10%2F2025®ionId=553248621593537217&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=11%2F10%2F2025&endDate=12%2F10%2F2025®ionId=553248621593537217&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=11%2F10%2F2025&endDate=12%2F10%2F2025®ionId=553248621593537217&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=11%2F10%2F2025&endDate=12%2F10%2F2025®ionId=553248621593537217&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=11%2F10%2F2025&endDate=12%2F10%2F2025®ionId=553248621593537217&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mosel Wine Region Explore the historic area of Mosel Wine Region—wineries, a scenic riverfront and sights from Mont Royal to S.A. Prum. [See all hotels in Mosel Wine Region](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25&adults=2®ionId=553248621593537217) ![Stolzenfels Castle](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/222000/222005-Stolzenfels-Castle.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Mosel Wine Region Hotel Reviews ## Find out more about Mosel Wine Region ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Mosel Wine Region? > The amount you pay for a 5-star hotel in Mosel Wine Region can vary according to the time of year you travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to land the best deal on a luxurious getaway. > > > > - Search for the lowest price per night from £63 ### What makes a hotel 5 stars in Mosel Wine Region? > Impeccable guest service is at the heart of every 5-star hotel in Mosel Wine Region. From the moment you arrive, staff attend to your every whim, whether recommending activities or providing a turn-down service. In addition, hotels have to offer top-rate conveniences to obtain a 5-star rating. These can include luxury bathrobes, on-site spa facilities, swimming pools, gastronomic kitchens and knowledgeable concierge. ### Are there any 5-star all-inclusive resorts in Mosel Wine Region? > Our handy filters are the best way to narrow down what you want. Select "All inclusive" and "5-star" to show the finest resorts in Mosel Wine Region where your lodging, meals, activities and entertainment are included in the upfront price. At these escapes, your holiday is pure extravagance from the moment you arrive. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [1 Star Hotels in Moselle - Nahe](https://www.expedia.co.uk/1Star-Moselle-Nahe-Hotels.s10-0-d6053286.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Boppard](https://www.expedia.co.uk/3Star-Boppard-Hotels.s30-0-d5723.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Cochem](https://www.expedia.co.uk/3Star-Cochem-Hotels.s30-0-d181170.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Hirzenach](https://www.expedia.co.uk/3Star-Hirzenach-Hotels.s30-0-d6246726.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Koblenz](https://www.expedia.co.uk/3Star-Koblenz-Hotels.s30-0-d5434.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Trier](https://www.expedia.co.uk/3Star-Trier-Hotels.s30-0-d5203.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Boppard](https://www.expedia.co.uk/4Star-Boppard-Hotels.s40-0-d5723.Travel-Guide-Filter-Hotels) - 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