Title: The 10 Best 5 Star Hotels in Cayos Zapatilla - 2026 Updated Prices | Expedia.co.uk

[Cayos Zapatilla Travel Guide](https://expedia.co.uk/Cayos-Zapatilla.dx6286134)[Hotels in Cayos Zapatilla](https://expedia.co.uk/Cayos-Zapatilla-Hotels.d6286134.Travel-Guide-Hotels)[Holiday Rentals in Cayos Zapatilla](https://expedia.co.uk/Cayos-Zapatilla-Holiday-Rentals.d6286134.Travel-Guide-HolidayRentals)[Flights to Cayos Zapatilla](https://expedia.co.uk/Cheap-Flights-To-Cayos-Zapatilla.d6286134.Travel-Guide-Flights)[Cayos Zapatilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cayos-Zapatilla.d6286134.Car-Hire-Guide)[Cayos Zapatilla Holidays](https://expedia.co.uk/Cayos-Zapatilla.d6286134.Holidays-City-Breaks)

![Paradise!
Unfortunately, it's only possible to go there with a guide.
There are a lot of different tour operators in Bocas del Toro, so a price comparison could be wise. ](https://images.trvl-media.com/place/6246124/962b07b0-9b6f-43f9-a3da-ab98125d9cc6.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Isa 

# Compare and book 5 Star hotels in Cayos Zapatilla, Bocas del Toro Province

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## Check availability on Cayos Zapatilla 5 Star Hotels

Tonight

[8 Dec - 9 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6286134&startDate=2025-12-08&endDate=2025-12-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[9 Dec - 10 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6286134&startDate=2025-12-09&endDate=2025-12-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6286134&startDate=2025-12-12&endDate=2025-12-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6286134&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Cayos Zapatilla 5 Star Hotels

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Cayos Zapatilla.

![NAYARA Bocas del Toro](https://images.trvl-media.com/lodging/52000000/51310000/51300100/51300004/605d473e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### NAYARA Bocas del Toro

Subdivision of Bocas del toro Isla Frangipani Bocas del Toro

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=22%2F12%2F2025&endDate=23%2F12%2F2025&selected=51300004&PinnedHotelID=51300004&HadPinnedHotel=true&regionId=6286134)

10/10 Exceptional! (56 reviews)

[](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Bocas-Bali.h51300004.Hotel-Information)

![Red Frog Beach Island Resort](https://images.trvl-media.com/lodging/5000000/4030000/4027300/4027252/312e0903_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Red Frog Beach Island Resort

Isla Bastimentos Bastimentos Bocas del Toro

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=22%2F12%2F2025&endDate=23%2F12%2F2025&selected=4027252&PinnedHotelID=4027252&HadPinnedHotel=true&regionId=6286134)

8.8/10 Excellent! (84 reviews)

[](https://expedia.co.uk/Isla-Bastimentos-Hotels-Red-Frog-Beach-Island-Resort.h4027252.Hotel-Information)

![Akwaba Lodge](https://images.trvl-media.com/lodging/97000000/96320000/96311700/96311639/8b07e3db_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Akwaba Lodge

isla solarte Bastimentos bocas del toro

£68

9 Dec - 10 Dec

includes taxes & fees

9.8/10 Exceptional! (14 reviews)

[](https://expedia.co.uk/Bastimentos-Hotels-Akwaba-Lodge.h96311639.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Cayos Zapatilla.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F12%2F2025&endDate=10%2F12%2F2025&regionId=6286134&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F12%2F2025&endDate=10%2F12%2F2025&regionId=6286134&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F12%2F2025&endDate=10%2F12%2F2025&regionId=6286134&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F12%2F2025&endDate=10%2F12%2F2025&regionId=6286134&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F12%2F2025&endDate=10%2F12%2F2025&regionId=6286134&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F12%2F2025&endDate=10%2F12%2F2025&regionId=6286134&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Cayos Zapatilla

Venture to sights like Zapatilla Island as you discover the local area in Cayos Zapatilla. 

[See all hotels in Cayos Zapatilla](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-22&endDate=2025-12-23&adults=2&regionId=6286134)

![Paradise!
Unfortunately, it's only possible to go there with a guide.
There are a lot of different tour operators in Bocas del Toro, so a price comparison could be wise. ](https://images.trvl-media.com/place/6246124/962b07b0-9b6f-43f9-a3da-ab98125d9cc6.jpg?impolicy=fcrop&w=899&h=600&p=1&q=high)

Photo by Isa 

## Top Cayos Zapatilla Hotel Reviews

## Find out more about Cayos Zapatilla

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