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Compare and book 4 Star hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana 4 Star Hotels

Tonight
28 Aug - 29 Aug
Tomorrow
29 Aug - 30 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

Our top choices for Southern Indiana 4-star hotels

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
£124
includes taxes & fees
8 Sept - 9 Sept
Galt House Hotel Trademark Collection by Wyndham

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Kara
£172
includes taxes & fees
30 Aug - 31 Aug
Omni Louisville Hotel

3. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Arnetta
£123
includes taxes & fees
6 Sept - 7 Sept
Hyatt Regency Louisville

4. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
Rachel
£129
includes taxes & fees
4 Sept - 5 Sept
The Brown Hotel

5. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Spencer
£113
includes taxes & fees
5 Sept - 6 Sept
Embassy Suites Louisville Downtown

6. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Candice
£159
includes taxes & fees
1 Sept - 2 Sept
21c Museum Hotel Louisville

7. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Rebekah
£117
includes taxes & fees
6 Sept - 7 Sept
Hotel Genevieve part of JdV by Hyatt

8. The Grady

The Grady
Downtown Louisville
£142
includes taxes & fees
30 Aug - 31 Aug
The Grady

9. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Lisa
£146
includes taxes & fees
4 Sept - 5 Sept
Louisville Marriott Downtown

10. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Jasmine
£168
includes taxes & fees
6 Sept - 7 Sept
Hotel Distil, Autograph Collection

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Kristen
£148
includes taxes & fees
7 Sept - 8 Sept
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
Jennifer
£83
includes taxes & fees
13 Sept - 14 Sept
DoubleTree by Hilton Evansville

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Jennifer
£131
includes taxes & fees
6 Sept - 7 Sept
Seelbach Hilton Louisville Downtown

14. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
Bonnie
£76
includes taxes & fees
1 Sept - 2 Sept
The Pepin Mansion Historic B&B

15. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Brad
£124
includes taxes & fees
1 Sept - 2 Sept
Stellar Suites

16. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Roy
£154
includes taxes & fees
31 Aug - 1 Sept
CozySuites at Nulu

17. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
United States
Chauntel
£124
includes taxes & fees
29 Aug - 30 Aug
stayAPT Suites Louisville North-Clarksville

18. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

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Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.
  • Search for the lowest price from £76
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

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