Title: The 10 Best 4 Star Hotels in Southern Indiana - 2026 Updated Prices | Expedia.co.uk [Southern Indiana Travel Guide](https://expedia.co.uk/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Holiday Rentals in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Holiday-Rentals.d6059635.Travel-Guide-HolidayRentals)[Flights to Southern Indiana](https://expedia.co.uk/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Things to do in Southern Indiana](https://expedia.co.uk/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities)[Southern Indiana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Indiana.d6059635.Car-Hire-Guide)[Southern Indiana Holidays](https://expedia.co.uk/Southern-Indiana.d6059635.Holidays-City-Breaks) ![Belle of Louisville featuring a ferry and a bay or harbour as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Indiana 4 Star Hotels Tonight [24 Feb - 25 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-02-24&endDate=2026-02-25&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [25 Feb - 26 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-02-25&endDate=2026-02-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southern Indiana 4-star hotels ![4 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/aa5bcd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9d86b349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/63654a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (4,093 reviews) "Rooms were clean and staff were friendly! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy £136 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/78105fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/0bb1b93b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,782 reviews) "Amazing stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin £174 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/edc62f96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/408d438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Louisville Downtown [](https://www.expedia.co.uk/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (1,167 reviews) "Great room and breakfast. Close to several nice restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal £107 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/764d3439.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brown Hotel [](https://www.expedia.co.uk/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) Downtown Louisville 9.4/10 Exceptional (1,200 reviews) "Beautiful old hotel with a fantastic bar in the lobby" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen [](https://www.expedia.co.uk/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/1b9613a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/9764f52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar, rooftop bar](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/8178d3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w3836h2558x4y3-11fbb096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Genevieve part of JdV by Hyatt [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,043 reviews) "Spotless room and courteous staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £118 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information) ![Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) Downtown Louisville 9.4/10 Exceptional (1,003 reviews) "Great room, super kind staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel £160 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/e017e8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/ecfda21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (VIP) | Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/b7d53e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/1a50697e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Louisville [](https://www.expedia.co.uk/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information) Downtown Louisville 8.8/10 Excellent (1,003 reviews) "Everything was just excellent on the day I stayed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peggy £140 includes taxes & fees 21 Mar - 22 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e116c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e68de90e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f5558cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/765b8556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Grady [](https://www.expedia.co.uk/Louisville-Hotels-The-Grady.h61215907.Hotel-Information) Downtown Louisville 9.4/10 Exceptional (1,006 reviews) "Such an amazing hotel...restaurant is delicious! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig £176 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Louisville-Hotels-The-Grady.h61215907.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/6f6867fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Bedroom | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/1c073add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Bedroom | Living area | 55-inch flat-screen TV with digital channels, Smart TV, pay films](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/14a187ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Louisville Marriott Downtown [](https://www.expedia.co.uk/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (1,001 reviews) "Very nice hotel. Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brad £157 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/ac66f01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/cf849375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/8fba23fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/939655b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Distil, Autograph Collection [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information) Downtown Louisville 9.6/10 Exceptional (449 reviews) "Great hotel & location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ana £160 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/cea1a8d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/1eebe4a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/60d711ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/954cf753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Evansville [](https://www.expedia.co.uk/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information) Downtown Evansville 8.6/10 Excellent (1,002 reviews) "The staff were extremely friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jill £104 includes taxes & fees 20 Mar - 21 Mar [](https://www.expedia.co.uk/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/5c616865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/f1158083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/c93e1deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/cb95631e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bourré Bonne Louisville, Curio Collection by Hilton [](https://www.expedia.co.uk/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (76 reviews) "i love this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) THANH £175 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/d22f4bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/12e6fe89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/w3839h2557x0y0-ff0d1f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seelbach Hilton Louisville Downtown [](https://www.expedia.co.uk/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information) Downtown Louisville 8.6/10 Excellent (1,002 reviews) "The area was congested but the motel was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Byrd £129 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/3f80acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Suite, 1 King Bed, Non Smoking | Premium bedding, down duvets, memory-foam beds, individually furnished](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/d0d55041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/af58ac58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down duvets, memory-foam beds, individually furnished](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stellar Suites [](https://www.expedia.co.uk/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information) Downtown Louisville 9.6/10 Exceptional (123 reviews) "The check-in process was simple and easy, the room was spotless and had so many amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Grace £138 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/ee4c1d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/19f1cd24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/3ff12f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/5cef01cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pepin Mansion Historic B&B [](https://www.expedia.co.uk/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information) New Albany 9.8/10 Exceptional (667 reviews) "The room was fantastic. Great location. Breakfast was excellent!! Mimi, the innkeeper, was gracious and very helpful with restaurant recommendations. Truly enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly £70 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/2e0c62b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/w2493h1667x0y0-491d9ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/af73a8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Non Smoking | In-room dining](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/57a6d9c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CozySuites at Nulu [](https://www.expedia.co.uk/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information) Downtown Louisville 8.0/10 Very good (27 reviews) "Wonderful stay - great spot and lots of great dining options and bars nearby " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roy £148 includes taxes & fees 17 Mar - 18 Mar [](https://www.expedia.co.uk/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/bb9c61a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e4c43211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e906c2d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e576ef26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Louisville North-Clarksville [](https://www.expedia.co.uk/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information) Clarksville 9.8/10 Exceptional (46 reviews) "room very good i love hotel ❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kartar [](https://www.expedia.co.uk/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/a0c5fbcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reserve on Main [](https://www.expedia.co.uk/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) Downtown Louisville 10/10 Exceptional (1 review) "Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) georgios £179 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) ![Family House, Multiple Beds | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/3b698b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Multiple Beds | Living area | Flat-screen TV, Netflix, video library](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/b618c806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/8410ecaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Multiple Beds | View from room](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/fa524ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb [](https://www.expedia.co.uk/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information) Sellersburg 9.4/10 Exceptional (10 reviews) "Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there," ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy [](https://www.expedia.co.uk/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/bdbbecb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/98663241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/66f2648f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Evansville Airport [](https://www.expedia.co.uk/Evansville-Hotels-Holiday-Inn-Evansville-Airport.h19261.Hotel-Information) Evansville 8.0/10 Very good (604 reviews) "Nice hotel but it doesn’t have a fridge in the room or microwave." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Evansville-Hotels-Holiday-Inn-Evansville-Airport.h19261.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Southern-Indiana-Hotels.s40-0-d6059635.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Southern-Indiana-Hotels.s40-0-d6059635.Travel-Guide-Filter-Hotels) ## Learn more about Southern Indiana Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake. [See all hotels in Southern Indiana](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-10&endDate=2026-03-11&adults=2®ionId=6059635) ![Belle of Louisville featuring a ferry and a bay or harbour as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Southern Indiana Hotel Reviews ![DoubleTree by Hilton Evansville](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/b1976648_y.jpg) ### DoubleTree by Hilton Evansville 10/10 Excellent "Didnt eat breakfast. " [](https://expedia.co.uk/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information) ## Find out more about Southern Indiana ## Frequently asked questions ### What are the best 4-star hotels in Southern Indiana? ### How much does it cost to stay in a 4-star hotel in Southern Indiana? > - Search for the lowest price from £70 ### What's the difference between 5-star and 4-star hotels in Southern Indiana? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Cottages in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Cottages.d6233674-aaCottages.Travel-Guide-Accommodation) - [Casino Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Casino-Hotel.0-0-d6233674-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Gay-Friendly-Hotel.0-0-d6233674-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Historic-Hotel.0-0-d6233674-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Hotel-With-A-Bar.0-0-d6233674-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with Balcony in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Hotels-With-Balcony.0-0-d6233674-tHotelswithBalcony.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Hotels-With-Smoking-Rooms.0-0-d6233674-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Luxury-Hotel.0-0-d6233674-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Omni Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Omni.0-0-d6233674--bOmni.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Pet-Friendly-Hotel.0-0-d6233674-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Riverside Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Riverside-Hotel.0-0-d6233674-triversidehotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Romantic-Hotel.0-0-d6233674-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Ski-Hotels.0-0-d6233674-tSkiHotels.Travel-Guide-Filter-Hotels) - [Spa Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Spa-Hotels.0-0-d6233674-tSpaHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Winery-Hotels.0-0-d6233674-tWineryHotels.Travel-Guide-Filter-Hotels) - [Ohio River Valley Hotels ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels) - [Lodges in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Lodges.d6233674-aaLodges.Travel-Guide-Accommodation) - [Villas in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Villas.d6233674-aaVillas.Travel-Guide-Accommodation) - [Casino Hotels in Southeastern Indiana ](https://www.expedia.co.uk/Southeastern-Indiana-Hotels-Casino-Hotel.0-0-d6233889-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Southeastern Indiana ](https://www.expedia.co.uk/Southeastern-Indiana-Hotels-Historic-Hotel.0-0-d6233889-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Southeastern Indiana ](https://www.expedia.co.uk/Southeastern-Indiana-Hotels-Hotel-With-Early-Check-In.0-0-d6233889-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Southwestern Indiana ](https://www.expedia.co.uk/Southwestern-Indiana-Hotels-Boutique-Hotel.0-0-d6233876-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Southwestern Indiana ](https://www.expedia.co.uk/Southwestern-Indiana-Hotels-Hotel-With-Connecting-Rooms.0-0-d6233876-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Southwestern Indiana ](https://www.expedia.co.uk/Southwestern-Indiana-Hotels-Hotels-With-Pool.0-0-d6233876-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Lakeside Hotels in Southwestern Indiana ](https://www.expedia.co.uk/Southwestern-Indiana-Hotels-Lakeside-Hotel.0-0-d6233876-tlakesidehotel.Travel-Guide-Filter-Hotels) - [Southwestern Indiana Hotels ](https://www.expedia.co.uk/Southwestern-Indiana-Hotels.d6233876.Travel-Guide-Hotels) - [Flights to Ohio River Valley ](https://www.expedia.co.uk/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights) - [Flights from Ohio River Valley ](https://www.expedia.co.uk/lp/flights/6233674/flights-from-ohio-river-valley) - [Ohio River Valley Holidays ](https://www.expedia.co.uk/Ohio-River-Valley.d6233674.Holidays-City-Breaks) - [Visit Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley.dx6233674) - [Visit Southeastern Indiana ](https://www.expedia.co.uk/Southeastern-Indiana.dx6233889) - [Visit Southwestern Indiana ](https://www.expedia.co.uk/Southwestern-Indiana.dx6233876) - [Golf Holiday Packages Southeastern Indiana ](https://www.expedia.co.uk/lp/theme-holidays/golf-holidays/6233889/Southeastern-Indiana) - [Mountain Holiday Packages Southeastern Indiana ](https://www.expedia.co.uk/lp/theme-holidays/mountain-holidays/6233889/Southeastern-Indiana) - [Ace Rental Cars in Ohio River Valley ](https://www.expedia.co.uk/Ace-Car-Rentals-In-Ohio-River-Valley.d6233674-c2.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Southeastern Indiana ](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Southeastern-Indiana.d6233889-c40.Car-Rental-Guide-Suppliers) - [Ohio River Valley Holiday Rentals ](https://www.expedia.co.uk/Ohio-River-Valley-Holiday-Rentals.d6233674.Travel-Guide-HolidayRentals) - [Book 4 Star Hotels in Southern Indiana on Expedia.com ](https://www.expedia.com/4Star-Southern-Indiana-Hotels.s40-0-d6059635.Travel-Guide-Filter-Hotels)