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Compare and book 4 Star hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana 4 Star Hotels

Our top choices for Southern Indiana 4-star hotels

4 restaurants; breakfast, lunch and dinner served

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,197 reviews)
"Great hotel & stay!"
United States
Jennifer
The price is £143
includes taxes & fees
6 Aug - 7 Aug
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,989 reviews)
"Beautiful, clean property with many things to do at and around the hotel."
United States
Brittany
The price is £175
includes taxes & fees
2 Aug - 3 Aug
Omni Louisville Hotel
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,009 reviews)
"Beautiful property, on-site restaurant was delicious. Beds very nice."
United States
nicolle
The price is £161
includes taxes & fees
2 Aug - 3 Aug
21c Museum Hotel Louisville
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,293 reviews)
"Well kept and the staff was very knowledgeable and helpful."
United States
Patricia
The price is £128
includes taxes & fees
27 Jul - 28 Jul
Embassy Suites Louisville Downtown
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,009 reviews)
"Beautiful Hotel!"
United States
Joseph
The price is £137
includes taxes & fees
2 Aug - 3 Aug
Hyatt Regency Louisville
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,003 reviews)
"Great location and friendly staff. Loved their bar and lobby area."
United States
Bikash
The price is £150
includes taxes & fees
9 Aug - 10 Aug
Louisville Marriott Downtown
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,010 reviews)
"Great place to stay!"
United States
Jennifer
The price is £144
includes taxes & fees
2 Aug - 3 Aug
The Grady
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (126 reviews)
"Great stay"
United States
Kristen
The price is £150
includes taxes & fees
2 Aug - 3 Aug
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (482 reviews)
"Great hotel and great staff."
United States
Jasmine
The price is £177
includes taxes & fees
2 Aug - 3 Aug
Hotel Distil, Autograph Collection
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,277 reviews)
"Nice staff, large room"
United States
Lisa
The price is £135
includes taxes & fees
4 Aug - 5 Aug
The Brown Hotel
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,108 reviews)
"Great place to stay and within walking distance of most things in the area."
United Kingdom
Debra
The price is £119
includes taxes & fees
27 Jul - 28 Jul
Hotel Genevieve part of JdV by Hyatt
Lobby

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
4.0 star property
Downtown Evansville
8.6 out of 10, Excellent, (1,003 reviews)
"The breakfast at the restaurant was very good. The hotel was very convenient for an event we attended at the Ford Center."
United States
Adrianna
The price is £94
includes taxes & fees
19 Jul - 20 Jul
DoubleTree by Hilton Evansville
Exterior

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,007 reviews)
"Room was very clean."
United States
Whitney
The price is £144
includes taxes & fees
27 Jul - 28 Jul
Seelbach Hilton Louisville Downtown
Property entrance

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (708 reviews)
"Lovely property and excellent breakfast"
United States
Jacob
The price is £70
includes taxes & fees
15 Jul - 16 Jul
The Pepin Mansion Historic B&B
Lounge

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (139 reviews)
"I had a great stay at Stellar Suites. Two quick nights in a very comfortable suite was exactly what was needed. Superior location and very responsive hosts. I’ll be sure and stay here the next time I’m in the area."
United States
Dustin
The price is £127
includes taxes & fees
14 Jul - 15 Jul
Stellar Suites
Exterior

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (51 reviews)
"Every thing was great. Especially impressed by the kitchen."
United States
Ronald
stayAPT Suites Louisville North-Clarksville
Seasonal outdoor pool

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
7.6 out of 10, Good, (32 reviews)
"Wonderful stay - great spot and lots of great dining options and bars nearby "
United States
Roy
The price is £152
includes taxes & fees
14 Jul - 15 Jul
CozySuites at Nulu
32-inch Smart TV with cable channels

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (3 reviews)
"The room was great and clean. Great location. "
United States
De'Carlon
The Reserve on Main
Exterior

Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
4.0 star property
Old Louisville
10.0 out of 10, Exceptional, (4 reviews)
"Inn Keepers were wonderful. "
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
Family House, Multiple Beds | Private kitchen | Fridge, microwave, oven, stovetop

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Explore plenty to see and do in Southern Indiana—live music, sports teams and popular sights like Holiday World and Splashin' Safari.

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Top Southern Indiana Hotel Reviews

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Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from £70

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.