Title: The 10 Best 4 Star Hotels in São Tomé Island - 2025 Updated Prices | Expedia.co.uk [São Tomé Island Travel Guide](https://expedia.co.uk/Sao-Tome-Island.dx3486)[Hotels in São Tomé Island](https://expedia.co.uk/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels)[Holiday Rentals in São Tomé Island](https://expedia.co.uk/Sao-Tome-Island-Holiday-Rentals.d3486.Travel-Guide-HolidayRentals)[Flights to São Tomé Island](https://expedia.co.uk/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights)[Things to do in São Tomé Island](https://expedia.co.uk/Things-To-Do-In-Sao-Tome-Island.d3486.Travel-Guide-Activities)[São Tomé Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Sao-Tome-Island.d3486.Car-Hire-Guide)[São Tomé Island Holidays](https://expedia.co.uk/Sao-Tome-Island.d3486.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/6bd54b7b17061af058501372a92d6b86.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 4 Star hotels in São Tomé Island, São Tomé and Príncipe ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on São Tomé Island 4 Star Hotels Tonight [9 Oct - 10 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-09&endDate=2025-10-10&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-10&endDate=2025-10-11&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top São Tomé Island 4 Star Hotels ![View from property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/fca34520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/7d8ab7b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/1d47642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omali São Tomé – Principe Collection São Tomé 9.4/10 Exceptional (59) "The employees really make the property a superstar. " £174 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Sao-Tome-Island-Hotels.s40-0-d3486.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Sao-Tome-Island-Hotels.s40-0-d3486.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in São Tomé Island. ![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pestana São Tomé Avenida Marginal 12 De Julho, São Tomé £177 2 Nov - 3 Nov includes taxes & fees 8/10 Very Good! (73 reviews) [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) Still don't see what you're looking for? [See all properties in São Tomé Island.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F10%2F2025&endDate=11%2F10%2F2025®ionId=3486&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F10%2F2025&endDate=11%2F10%2F2025®ionId=3486&star=40&star=40&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F10%2F2025&endDate=11%2F10%2F2025®ionId=3486&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F10%2F2025&endDate=11%2F10%2F2025®ionId=3486&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F10%2F2025&endDate=11%2F10%2F2025®ionId=3486&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F10%2F2025&endDate=11%2F10%2F2025®ionId=3486&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about São Tomé Island Venture to sights like São Nicolau Waterfall and Pico São Tomé as you discover São Tomé Island. [See all hotels in São Tomé Island](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-23&endDate=2025-10-24&adults=2®ionId=3486) ![](https://mediaim.expedia.com/destination/1/6bd54b7b17061af058501372a92d6b86.jpg?impolicy=fcrop&w=899&h=520&p=1&q=high) ## Top São Tomé Island Hotel Reviews ![Omali São Tomé – Principe Collection](//images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203_y.jpg) ### Omali São Tomé – Principe Collection 8/10 Good "It’s a great resort, with friendly staff who " [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ## Find out more about São Tomé Island ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in São Tomé Island? > With Expedia's filter tool, locking in an awesome deal on a 4-star hotel in São Tomé Island just got simpler. Start by keying in your chosen travel dates and length of your holiday. Then sort the results by price and pick a hotel that best suits your style and budget. > > > > - Search for the lowest price from £177 ### What's the difference between 5-star and 4-star hotels in São Tomé Island? > Offering an inviting traveller experience and upmarket surroundings, 4-star hotels are a fabulous option for your São Tomé Island trip. These kinds of stays generally come with loads of useful amenities that make it simple to unpack and recharge — think complimentary bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to spoil you with exclusive perks and amenities. Round-the-clock concierge service, oversized bathrooms and fine dining are typically featured at these plush properties. ### Does São Tomé Island have any 4-star all-inclusive resorts? > Use our "All inclusive" filter to search for your next escape in São Tomé Island where just about everything is taken care of, from your room to your meals, activities and entertainment. 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