Title: The 10 Best 4 Star Hotels in Multiple Use Area Lake Atitlan Basin - 2025 Updated Prices | Expedia.co.uk [Multiple Use Area Lake Atitlan Basin Travel Guide](https://expedia.co.uk/Multiple-Use-Area-Lake-Atitlan-Basin.dx649200964002652160)[Hotels in Multiple Use Area Lake Atitlan Basin](https://expedia.co.uk/Multiple-Use-Area-Lake-Atitlan-Basin-Hotels.d649200964002652160.Travel-Guide-Hotels)[Holiday Rentals in Multiple Use Area Lake Atitlan Basin](https://expedia.co.uk/Multiple-Use-Area-Lake-Atitlan-Basin-Holiday-Rentals.d649200964002652160.Travel-Guide-HolidayRentals)[Flights to Multiple Use Area Lake Atitlan Basin](https://expedia.co.uk/Cheap-Flights-To-Multiple-Use-Area-Lake-Atitlan-Basin.d649200964002652160.Travel-Guide-Flights)[Multiple Use Area Lake Atitlan Basin Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Multiple-Use-Area-Lake-Atitlan-Basin.d649200964002652160.Car-Hire-Guide)[Multiple Use Area Lake Atitlan Basin Holidays](https://expedia.co.uk/Multiple-Use-Area-Lake-Atitlan-Basin.d649200964002652160.Holidays-City-Breaks) ![Lake Atitlan which includes mountains, a lake or waterhole and landscape views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/69000/69985-Lake-Atitlan.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 4 Star hotels in Multiple Use Area Lake Atitlan Basin, Guatemala - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Multiple Use Area Lake Atitlan Basin 4 Star Hotels Tonight [8 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=649200964002652160&startDate=2025-11-08&endDate=2025-11-09&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Nov - 10 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=649200964002652160&startDate=2025-11-09&endDate=2025-11-10&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=649200964002652160&startDate=2025-11-14&endDate=2025-11-16&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=649200964002652160&startDate=2025-11-21&endDate=2025-11-23&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Multiple Use Area Lake Atitlan Basin 4 Star Hotels ![Suite (Santa Catarina Master) | View from room](https://images.trvl-media.com/lodging/16000000/15650000/15644600/15644513/501fb8a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 6:00 PM, pool loungers](https://images.trvl-media.com/lodging/16000000/15650000/15644600/15644513/7b159310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Santa Catarina Master) | Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/16000000/15650000/15644600/15644513/781e2a91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Santa Clara Suite | View from room](https://images.trvl-media.com/lodging/16000000/15650000/15644600/15644513/8267478a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Palopó - Relais & Chateaux Santa Catarina Palopo 9.2/10 Wonderful (219) " " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victor £400 includes taxes & fees 12 Nov - 13 Nov [](https://www.expedia.co.uk/Panajachel-Hotels-Hotel-Casa-Palopo.h15644513.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/19000000/18130000/18124800/18124797/b56ff9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/19000000/18130000/18124800/18124797/83a4c73c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18130000/18124800/18124797/e8ac50ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18130000/18124800/18124797/1269d607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latam Hotel Plaza Pradera Quetzaltenango Quetzaltenango 9.4/10 Exceptional (402) "High quality of the hotel , staff well trained, all are very kind . Clean , comfort rooms ! Very well satisfied with the hotel in Quetzaltenango!!!!’" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Silvia [](https://www.expedia.co.uk/Quetzaltenango-Hotels-Latam-Hotel-Plaza-Pradera-Quetzaltenango.h18124797.Hotel-Information) ![Handrails in hallways](https://images.trvl-media.com/lodging/20000000/19870000/19868400/19868310/e5c1d214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/20000000/19870000/19868400/19868310/c8698e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19870000/19868400/19868310/5c821b04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed | 1 bedroom, premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/20000000/19870000/19868400/19868310/52ed3f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Casa Morasan Quetzaltenango 9.4/10 Exceptional (133) "Excellent hotel great location and amazing services Thank you to Karen from de front desk team and Fernanda from the restaurant team." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Onay £84 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Quetzaltenango-Hotels-Hotel-Boutique-Casa-Morasan.h19868310.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/102000000/101310000/101306700/101306611/fd731124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Loft | Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/102000000/101310000/101306700/101306611/2944c8fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Loft | Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/102000000/101310000/101306700/101306611/db33ca54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Double Room | Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/102000000/101310000/101306700/101306611/c808e006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Art & Coffee Santa Cruz La Laguna 8.4/10 Very good (5) "Enjoyed my stay at Art & Coffee. Owned by expat Americans living their dream. Very positive and friendly people. Large single story rooms with outdoor patios. I opted to eat at the adjacent cafe inidgo every morning - which has great food and waterfront view. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colin £14 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Santa-Cruz-La-Laguna-Hotels-Art-Coffee.h101306611.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/107000000/106550000/106544100/106544093/edb0466a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, Bathtub, Mountain View | Living area](https://images.trvl-media.com/lodging/107000000/106550000/106544100/106544093/aef5e9cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier House, Bathtub, Garden View | Private kitchen | Full-sized fridge, stovetop, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/107000000/106550000/106544100/106544093/9844d910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/107000000/106550000/106544100/106544093/0406d0ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sarnai San Marcos La Laguna 9.4/10 Exceptional (26) "Beautiful place to stay in San Marcos and extremely walkable to everything including the docks. A little difficult when navigating with luggage but everything else was a breeze. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gazale £94 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/San-Marcos-La-Laguna-Hotels-Sarnai.h106544093.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/25000000/24370000/24362000/24361961/976eae65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/25000000/24370000/24362000/24361961/71054a9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 King Bed, Lake View, Lakeside | 1 bedroom, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/25000000/24370000/24362000/24361961/5839cdf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 King Bed, Lake View, Lakeside | View from room](https://images.trvl-media.com/lodging/25000000/24370000/24362000/24361961/c8b46236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Prana Hotel In Atitlan Santa Cruz La Laguna 9.4/10 Exceptional (49) "One of the best places I’ve ever stayed. Grounds were beautiful, staff was on point and food was delicious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Abhilasha £145 includes taxes & fees 28 Nov - 29 Nov [](https://www.expedia.co.uk/Santa-Cruz-La-Laguna-Hotels-Casa-Prana-Hotel-In-Atitlan.h24361961.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12020000/12016500/12016415/a6491e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, free WiFi](https://images.trvl-media.com/lodging/13000000/12020000/12016500/12016415/6c834e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12020000/12016500/12016415/5c44dc19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12020000/12016500/12016415/4347e67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Laguna Lodge Eco-Resort & Nature Reserve Santa Cruz La Laguna 8.4/10 Very good (28) "The place is magic. You are smiling during the stay without knowing it. We love the connection with the lake and their people. The amazing staff is another big plus. Congratulations to the owners/ managers for this jewel in Guatemala." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Azarias [](https://www.expedia.co.uk/Santa-Cruz-La-Laguna-Hotels-Laguna-Lodge-Eco-Resort-Nature-Reserve.h12016415.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/93000000/92300000/92296900/92296856/a5b376ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92300000/92296900/92296856/ae2322e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 Bedroom | 3 bedrooms, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/93000000/92300000/92296900/92296856/97761a28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92300000/92296900/92296856/84c106c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Restaurante Premier La Esperanza 8.0/10 Very good (2) "Hotel conforme para una noche de trabajo, simple y correcto sin mas." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ignacio [](https://www.expedia.co.uk/La-Esperanza-Hotels-Hotel-Y-Restaurante-Premier.h92296856.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Multiple-Use-Area-Lake-Atitlan-Basin-Hotels.s40-0-d649200964002652160.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Multiple-Use-Area-Lake-Atitlan-Basin-Hotels.s40-0-d649200964002652160.Travel-Guide-Filter-Hotels) ## Learn more about Multiple Use Area Lake Atitlan Basin Discover things to see and do in Multiple Use Area Lake Atitlan Basin as you venture to popular sights like Lake Atitlán. [See all hotels in Multiple Use Area Lake Atitlan Basin](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-22&endDate=2025-11-23&adults=2®ionId=649200964002652160) ![Santa Cruz La Laguna featuring a city and landscape views](https://images.trvl-media.com/place/6219548/d6edcc9e-ec7c-49f0-bf64-08bb9a6365af.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Multiple Use Area Lake Atitlan Basin Hotel Reviews ![Hotel Casa Palopó - Relais & Chateaux](//images.trvl-media.com/lodging/16000000/15650000/15644600/15644513/501fb8a1_y.jpg) ### Hotel Casa Palopó - Relais & Chateaux 10/10 Excellent "Everything was clean and sparkling. Casa is a totally colonial experience with steps and cobblestones and the most amazing panoramic view of the Lake and three volcanoes." [](https://expedia.co.uk/Panajachel-Hotels-Hotel-Casa-Palopo.h15644513.Hotel-Information) ## Find out more about Multiple Use Area Lake Atitlan Basin ## Explore a world of travel with Expedia - Accommodation - Packages - [Hotels with Room Service in Western Highlands](https://www.expedia.co.uk/Western-Highlands-Hotels-Hotel-With-Room-Service.0-0-d6053901-thotelwithroomservice.Travel-Guide-Filter-Hotels) - [Western Highlands Hotels](https://www.expedia.co.uk/Western-Highlands-Hotels.d6053901.Travel-Guide-Hotels) - [Western Highlands Holidays](https://www.expedia.co.uk/Western-Highlands.d6053901.Holidays-City-Breaks) - [Visit Western Highlands](https://www.expedia.co.uk/Western-Highlands.dx6053901)