Title: The 10 Best 4 Star Hotels in Isla del Rey - 2026 Updated Prices | Expedia.co.uk [Isla del Rey Travel Guide](https://expedia.co.uk/Isla-Del-Rey.dx6336628)[Hotels in Isla del Rey](https://expedia.co.uk/Isla-Del-Rey-Hotels.d6336628.Travel-Guide-Hotels)[Holiday Rentals in Isla del Rey](https://expedia.co.uk/Isla-Del-Rey-Holiday-Rentals.d6336628.Travel-Guide-HolidayRentals)[Flights to Isla del Rey](https://expedia.co.uk/Cheap-Flights-To-Isla-Del-Rey.d6336628.Travel-Guide-Flights)[Isla del Rey Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Isla-Del-Rey.d6336628.Car-Hire-Guide)[Isla del Rey Holidays](https://expedia.co.uk/Isla-Del-Rey.d6336628.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 4 Star hotels in Isla del Rey, Panamá Province - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - 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