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Check prices for these dates

Next weekend
3 Jul - 5 Jul
In two weeks
10 Jul - 12 Jul

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Star rating

Our top choices for 21c Museum Hotel hotels

Lobby

1. The Grady

The Grady
4.0 star property
Downtown Louisville, < 0.1 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,001 reviews)
"We loved this hotel. It was clean, close to our activities and the staff was friendly."
United States
Elizabeth
The price is £140
includes taxes & fees
30 Jun - 1 Jul
The Grady
Front of property

2. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,004 reviews)
"Excellent stay!"
United States
William
The price is £139
includes taxes & fees
27 Jul - 28 Jul
21c Museum Hotel Louisville
Terrace/patio

3. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, < 0.1 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,007 reviews)
"The staff was super friendly and the location was perfect!"
United States
Lateshia
The price is £117
includes taxes & fees
5 Jul - 6 Jul
Homewood Suites by Hilton Louisville Downtown, KY
Terrace/patio

4. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.5 mi from 21c Museum Hotel
9.6 out of 10, Exceptional, (475 reviews)
"Love staying here when we are in Louisville. "
United States
Edward
The price is £187
includes taxes & fees
26 Jul - 27 Jul
Hotel Distil, Autograph Collection
3 bars/lounges, cocktail bar, lobby lounge

5. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.5 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,949 reviews)
"Great stay!"
United States
Cortney
The price is £142
includes taxes & fees
1 Jul - 2 Jul
Omni Louisville Hotel
Terrace/patio

6. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.5 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (119 reviews)
"Great stay"
United States
Kristen
The price is £160
includes taxes & fees
5 Jul - 6 Jul
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Interior entrance

7. Market Street Inn

Market Street Inn
3.5 star property
1.3 mi from 21c Museum Hotel
9.8 out of 10, Exceptional, (121 reviews)
"Great place near quite a few shops and restaurants. Close enough to downtown. Breakfast was nice and everyone was very welcoming."
United States
Anissa
The price is £143
includes taxes & fees
29 Jun - 30 Jun
Market Street Inn
Lobby

8. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 0.8 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,252 reviews)
"Nice staff, large room"
United States
Lisa
The price is £143
includes taxes & fees
29 Jun - 30 Jun
The Brown Hotel
Property amenity

9. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.2 mi from 21c Museum Hotel
9.2 out of 10, Wonderful, (653 reviews)
"Great place to stay! I would definitely stay here again!"
United States
Dana Jean
The price is £102
includes taxes & fees
29 Jun - 30 Jun
Towneplace Suites By Marriott Louisville Downtown
Interior entrance

10. Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 1.8 mi from 21c Museum Hotel
10.0 out of 10, Exceptional, (24 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is £273
includes taxes & fees
29 Jun - 30 Jun
Louisville Bourbon Inn
Dining

11. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 0.7 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,003 reviews)
"Huge surprise for the price, very pleasant room and stay!"
United States
Jeff
The price is £101
includes taxes & fees
5 Jul - 6 Jul
Cambria Hotel Louisville Downtown-Whiskey Row
4 restaurants; breakfast, lunch and dinner served

12. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.3 mi from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,154 reviews)
"Nice place to stay."
United States
Jeron
The price is £146
includes taxes & fees
29 Jun - 30 Jun
Galt House Hotel Trademark Collection by Wyndham
Interior entrance

13. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.5 mi from 21c Museum Hotel
9.2 out of 10, Wonderful, (787 reviews)
"Great and fun spot! Enjoyed our one night here"
United States
Adam
The price is £93
includes taxes & fees
26 Jul - 27 Jul
Moxy Louisville Downtown
Lounge

14. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 1.4 mi from 21c Museum Hotel
9.6 out of 10, Exceptional, (137 reviews)
"Lovely stay . Great self-contained room with everything Nulu has to offer on your doorstep..1st night there was some live music going on at across the street at Taj bar which kept me awake , but apart from that little bump i cannot fault the room... they have lots more in the back further away from street so worth checking. Excellent stay and will def return if im back !!"
United Kingdom
Andy
The price is £129
includes taxes & fees
29 Jun - 30 Jun
Stellar Suites
Front of property

15. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
2.0 star property
Old Louisville, 1.7 mi from 21c Museum Hotel
9.6 out of 10, Exceptional, (131 reviews)
"Unique rooms Excellent breakfast"
United States
Annette
The price is £126
includes taxes & fees
29 Jun - 30 Jun
DuPont Mansion Bed & Breakfast
2 restaurants; breakfast and dinner served

16. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 1.3 mi from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,046 reviews)
"Excellent location and clean hotel!"
United States
Monica
The price is £109
includes taxes & fees
29 Jun - 30 Jun
Tempo By Hilton Louisville Downtown Nulu
Restaurant

17. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.5 mi from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location!"
United States
Sompathana
The price is £119
includes taxes & fees
5 Jul - 6 Jul
Aloft by Marriott Louisville Downtown
Reception

18. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.5 mi from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,278 reviews)
"Well kept and the staff was very knowledgeable and helpful."
United States
Patricia
The price is £130
includes taxes & fees
5 Jul - 6 Jul
Embassy Suites Louisville Downtown
Lobby

19. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 0.4 mi from 21c Museum Hotel
8.8 out of 10, Excellent, (1,001 reviews)
"Great location and easy parking. The staff was very friendly as well."
United States
Thomas
The price is £126
includes taxes & fees
2 Jul - 3 Jul
Hyatt Regency Louisville
Exterior

20. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.5 mi from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location and friendly staff. Loved their bar and lobby area."
United States
Bikash
The price is £168
includes taxes & fees
26 Jul - 27 Jul
Louisville Marriott Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to 21c Museum Hotel

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,001 reviews
View
Front of property
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,004 reviews
View
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,007 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
475 reviews
View
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
1,949 reviews
View

Top 21c Museum Hotel Hotel Reviews

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

10/10 Excellent
"Great Hotel close to everything!"
Nathan C. 2-night trip
Posted 1 hour ago
Embassy Suites Louisville Downtown

Hotels near other 21c Museum Hotel attractions

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/5 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
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Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 260 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Homewood Suites by Hilton Louisville Downtown, KY.
How many hotels are there near 21c Museum Hotel?
Expedia has 260 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Union Station. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.