The Best Hotels Closest to Louisville Science Center in Louisville - 2026 Updated Prices

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

A covered outdoor seating area with wicker furniture and a wooden railing.

1. Louisville Bourbon Inn

Old Louisville, 1.8 mi from Louisville Science Center

Roy

£244

includes taxes & fees

11 Oct - 12 Oct

A wooden staircase with a balustrade leading to a landing.

A two-story brick building with a white porch and a sign reading "Hotel".

A brick building with a covered porch, columns, and potted plants.

A bedroom with a bed, a dresser, a television, and a desk with a lamp.

2. Market Street Inn

1.3 mi from Louisville Science Center

Holly

£167

includes taxes & fees

29 Sept - 30 Sept

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A room with a red velvet sofa, a blue armchair, and a small round table with books.

A living room with a sofa, a fireplace, a staircase, and a chandelier.

A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

3. DuPont Mansion Bed & Breakfast

Old Louisville, 1.7 mi from Louisville Science Center

Casey

£160

includes taxes & fees

29 Sept - 30 Sept

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

A grand lobby with ornate ceiling, large windows, and classic furniture.

4. The Brown Hotel

Downtown Louisville, 0.8 mi from Louisville Science Center

Meghan

£119

includes taxes & fees

29 Oct - 30 Oct

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.

A swimming pool with lounge chairs and a view of the city.

A spacious lobby with a large seating area, a chandelier, and a patterned rug.

5. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, < 0.1 mi from Louisville Science Center

Kelly

£107

includes taxes & fees

25 Oct - 26 Oct

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

6. Hotel Distil, Autograph Collection

Downtown Louisville, 0.6 mi from Louisville Science Center

Adam

£210

includes taxes & fees

29 Oct - 30 Oct

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.

A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.

7. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 1.3 mi from Louisville Science Center

Addison

£109

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

A modern hotel room with a large bed, a city view, and a unique headboard design.

A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

8. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.5 mi from Louisville Science Center

Cameron

£189

includes taxes & fees

4 Oct - 5 Oct

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

9. Stellar Suites

East Market District, 1.4 mi from Louisville Science Center

Benton

£124

includes taxes & fees

29 Sept - 30 Sept

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A building with a sign reading "THE GRADY" at the entrance.

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

10. The Grady

Downtown Louisville, 0.1 mi from Louisville Science Center

Bruce

£155

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with wicker furniture and a fire pit.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

A modern living room with a sofa, armchairs, a coffee table, and a TV.

A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.

11. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.2 mi from Louisville Science Center

Scott

£98

includes taxes & fees

25 Oct - 26 Oct

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

A modern bar area with sofas, tables, and a bar stocked with bottles.

12. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.6 mi from Louisville Science Center

Angela

£118

includes taxes & fees

4 Oct - 5 Oct

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A bedroom with a bed, a chair, a TV, and a window with curtains.

A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

A brightly lit grocery store with yellow shelving and a central checkout counter.

13. Hotel Genevieve part of JdV by Hyatt

East Market District, 1.3 mi from Louisville Science Center

Tyler

£135

includes taxes & fees

4 Oct - 5 Oct

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

14. Moxy Louisville Downtown

Downtown Louisville, 0.6 mi from Louisville Science Center

Bryan

£114

includes taxes & fees

11 Oct - 12 Oct

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

15. AC Hotel Louisville Downtown

East Market District, 1.3 mi from Louisville Science Center

Jen

£131

includes taxes & fees

25 Oct - 26 Oct

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

A balcony with a view of a river, a bridge, and a cityscape.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

16. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.3 mi from Louisville Science Center

Saud

£134

includes taxes & fees

27 Oct - 28 Oct

A covered patio with a stone wall, a glass table, and a bench.

A stone house with a balcony, a front door, and a staircase leading to the entrance.

A grand room with a fireplace, a staircase, and a chandelier.

17. Central Park Bed & Breakfast

Old Louisville, 1.8 mi from Louisville Science Center

Brittany

£138

includes taxes & fees

15 Oct - 16 Oct

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

A modern hotel room with a living area, a dining area, and a bedroom.

A hotel dining area with long tables, booths, and a bar.

A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.

18. Embassy Suites Louisville Downtown

Downtown Louisville, 0.5 mi from Louisville Science Center

Maurica

£121

includes taxes & fees

29 Oct - 30 Oct

A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

A reception area with marble counters, modern pendant lighting, and potted orchids.

A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

19. Louisville Marriott Downtown

Downtown Louisville, 0.5 mi from Louisville Science Center

Jacobi

£190

includes taxes & fees

12 Oct - 13 Oct

A modern interior with a curved wall featuring vertical lines and geometric patterns.

A modern dining area with blue and red seating, wooden tables, and decorative hanging lamps.

A modern lobby with a curved seating area, a red ottoman, and a television screen.

20. Holiday Inn Express & Suites Louisville Downtown by IHG

Downtown Louisville, 0.1 mi from Louisville Science Center

Carlos

£93

includes taxes & fees

25 Oct - 26 Oct

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Compare popular hotels close to Louisville Science Center

Property	Property class	Guest rating
Louisville Bourbon Inn	10.0 Exceptional 25 reviews	View
Market Street Inn	9.8 Exceptional 125 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 147 reviews	View
The Brown Hotel	9.4 Exceptional 1,331 reviews	View
Homewood Suites by Hilton Louisville Downtown, KY	9.4 Exceptional 1,006 reviews	View

Top Louisville Science Center Hotel Reviews

The Brown Hotel

10/10 Excellent

"We loved this hotel. We could not ask for a more wonderful stay and we ate what was probably the best dinner ever in the restaurant there. We just wish we could have stayed longer."

Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent

"Kitchen"

Holiday Inn Louisville Downtown by IHG

8/10 Good

"Lots of key trouble, kept having to get keys re-activated. Staff was good and the hotel grounds/common areas/rooms were updated and nice."

Embassy Suites Louisville Downtown

10/10 Excellent

"Staff was super helpful. Breakfast was delicious! Clean property and good location"

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent

"Great place"

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"Everything was tidy and welcoming. Staff was very nice and helpful."

The Reserve on Main

10/10 Excellent

"The location was fantastic, the building, guest rooms, and common areas were in pristine condition, very clean, sleek design, well stocked with everything you could possibly need. Really enjoyed the speak easy in the lower level and the opportunity to have a nightcap in the private lounge on our floor. We appreciated the security system build into the elevator to limit access to only hotel guests. We could not have been more pleased with our stay. The owners communicated well and were helpful in answering questions. Highly recommend!!!"

Cambria Hotel Louisville Downtown-Whiskey Row

8/10 Good

"We really liked the location of the hotel. It was nice to have a restaurant and bar on property as well. Two complaints would be water pressure in the shower and you could hear your neighbors. They weren’t being loud either; not sure if walls were thin!"

Hyatt Regency Louisville

10/10 Excellent

"Friendly staff, great location, easy parking, breakfast was good, clean"

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)

Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

Search Hotels Near Louisville Science Center, Louisville

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Be picky

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Our top choices for Louisville Science Center hotels

1. Louisville Bourbon Inn

2. Market Street Inn

3. DuPont Mansion Bed & Breakfast

4. The Brown Hotel

5. Homewood Suites by Hilton Louisville Downtown, KY

6. Hotel Distil, Autograph Collection

7. Tempo By Hilton Louisville Downtown Nulu

8. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

9. Stellar Suites

10. The Grady

11. Towneplace Suites By Marriott Louisville Downtown

12. Aloft by Marriott Louisville Downtown

13. Hotel Genevieve part of JdV by Hyatt

14. Moxy Louisville Downtown

15. AC Hotel Louisville Downtown

16. Galt House Hotel Trademark Collection by Wyndham

17. Central Park Bed & Breakfast

18. Embassy Suites Louisville Downtown

19. Louisville Marriott Downtown

20. Holiday Inn Express & Suites Louisville Downtown by IHG

Compare popular hotels close to Louisville Science Center

Top Louisville Science Center Hotel Reviews

The Brown Hotel

Towneplace Suites By Marriott Louisville Downtown

Holiday Inn Louisville Downtown by IHG

Embassy Suites Louisville Downtown

Holiday Inn Express & Suites Louisville Downtown by IHG

Homewood Suites by Hilton Louisville Downtown, KY

The Reserve on Main

Cambria Hotel Louisville Downtown-Whiskey Row

Hyatt Regency Louisville

Other attractions near Louisville Science Center

Louisville Slugger Museum

Muhammad Ali Center

Frazier International History Museum

Kentucky Center for the Performing Arts

Kentucky Museum of Art and Craft

Golden Statue of David

SAR Genealogical Research Library: NSSAR Library

Louisville Glassworks

Frequently asked questions