Scenic view of Fountain Lakes Park, in St. Charles, MO with colorful Autumn foliage and a cloudy sky reflected in a lake

Compare and book 4 Star hotels in St. Charles, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles 4 Star Hotels

Our top choices for St. Charles 4-star hotels

Lobby

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,119 reviews)
"This was one of the nicest hotels I have ever stayed at for a very affordable price. We would definitely stay here again."
United States
Elisha
The price is £132
includes taxes & fees
20 Jun - 21 Jun
Hyatt Regency St. Louis at The Arch
Meeting facility

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,090 reviews)
"Great location to the airport and staff was very welcoming!"
United States
James
The price is £120
includes taxes & fees
19 Jul - 20 Jul
Renaissance St. Louis Airport Hotel
Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, pool loungers

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (731 reviews)
"Dinning and pool areas were enjoyable."
United States
Robert
The price is £136
includes taxes & fees
28 Jun - 29 Jun
Le Méridien St. Louis Clayton
Seasonal outdoor pool

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1,001 reviews)
"Great hotel!"
United States
Terence Peter
The price is £187
includes taxes & fees
28 Jun - 29 Jun
The Royal Sonesta Chase Park Plaza St. Louis
Restaurant

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,916 reviews)
"Great stay!"
United States
Quentin
The price is £135
includes taxes & fees
21 Jun - 22 Jun
21C Museum Hotel St Louis
Exterior

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very good, (1,029 reviews)
"The room was nice and the staff was friendly. Perfect spot to stay if you’re going out on the town for the night."
United States
Jenna
The price is £137
includes taxes & fees
19 Jul - 20 Jul
Marriott St. Louis Grand
Breakfast, lunch and dinner served

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,208 reviews)
"Hotel was stunning, breakfast was amazing and the location was perfect!"
United States
Julie
The price is £143
includes taxes & fees
21 Jun - 22 Jun
Live by Loews - St.Louis
5 restaurants; breakfast, lunch, dinner and brunch served

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,615 reviews)
"Would stay again in a heartbeat!"
United States
Austin
The price is £84
includes taxes & fees
1 Jul - 2 Jul
River City Casino & Hotel
3 bars/lounges, rooftop bar

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,169 reviews)
"Beautiful hotel"
United States
Zoobin
The price is £153
includes taxes & fees
13 Jul - 14 Jul
Hilton St. Louis at the Ballpark
Gastropub

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,001 reviews)
"Great unique hotel."
United States
Michelle
The price is £144
includes taxes & fees
21 Jun - 22 Jun
The Cheshire
Property amenity

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,968 reviews)
"Super convenient location, friendly staff, cool decor! Will definitely stay here again."
United States
Lindsay
The price is £127
includes taxes & fees
29 Jun - 30 Jun
Moonrise Hotel
Bar (on property)

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,310 reviews)
"The staff could not have been nicer even holding our luggage before and after checkout. The beds were super comfy and the rooms extra spacious with a living room area separate from the sleeping space. And just a short walk to Busch Stadium and the arch!!"
United States
Cherie
The price is £97
includes taxes & fees
12 Jul - 13 Jul
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Coffee shop

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,003 reviews)
"Great stay!"
United States
Matiah
The price is £153
includes taxes & fees
19 Jul - 20 Jul
Ameristar Casino Resort and Spa
Premium bedding, down duvets, pillow-top beds, in-room safe

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,000 reviews)
"The staff was pleasant and the property was clean."
United States
Bayyan
The price is £124
includes taxes & fees
28 Jun - 29 Jun
The Westin St. Louis
Lobby lounge

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,025 reviews)
"Great staff clean property nice location"
United States
Karen
The price is £122
includes taxes & fees
28 Jun - 29 Jun
Drury Plaza Hotel St. Louis Brentwood
In-room safe, desk, blackout curtains, iron/ironing board

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very good, (1,001 reviews)
"Beautiful hotel in a convenient locations. Walking distance to great restaurants and coffee shops."
United States
Gary
The price is £116
includes taxes & fees
2 Jul - 3 Jul
DoubleTree by Hilton St. Louis Forest Park
Lobby

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,018 reviews)
"Great stay and so much to do close by!"
United States
Rachel
The price is £143
includes taxes & fees
17 Jul - 18 Jul
St. Louis Union Station Hotel, Curio Collection by Hilton
Lobby

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,086 reviews)
"Great location and staff."
United States
Colette
The price is £116
includes taxes & fees
12 Jul - 13 Jul
Hilton Pennywell St. Louis at the Arch
Restaurant

Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,002 reviews)
"Lovely"
United States
Yvonne
The price is £134
includes taxes & fees
5 Jul - 6 Jul
Marriott St. Louis Airport
Exterior

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,316 reviews)
"Definitely would stay again."
United States
Travis
The price is £110
includes taxes & fees
28 Jun - 29 Jun
Embassy Suites by Hilton St. Louis Downtown
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Charles.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
The price is £438 per night from 21 Jun to 22 Jun
£438
21 Jun - 22 Jun
includes taxes & fees
9.2/10 Wonderful! (570 reviews)
Still don't see what you're looking for?
See all properties in St. Charles.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

See all hotels in St. Charles
Dramatic sunrise panoramic view of the Veterans Memorial Bridge over the Missouri River at St. Charles, MO

Top St. Charles Hotel Reviews

River City Casino & Hotel

River City Casino & Hotel

10/10 Excellent
"Beautiful rooms with great showers! Smoking is permitted at some places on property so there is a faint odor of smoke everywhere bit you can tell the staff work hard to keep everything clean. The Asian noodle restaurant on property is delicious!"
Kyle 2-night trip
Posted less than an hour ago
River City Casino & Hotel

Find out more about St. Charles

Frequently asked questions

What are the best 4-star hotels in St. Charles?
Look forward to 4-star hotel comfort at Ameristar Casino Resort and Spa. Rated highly by many of our guests, it features spa facilities and a spa tub. Also check out DoubleTree by Hilton St. Louis - Westport. Concierge services and a pillowtop mattress make this retreat another in-demand pick in St. Charles.
How much does it cost to stay in a 4-star hotel in St. Charles?
To find a 4-star hotel in St. Charles that fits your budget, use Expedia's sort and search filters. Check out the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also list your results by the most wallet-friendly option first.

  • Search for the lowest price from £312

What's the difference between 5-star and 4-star hotels in St. Charles?
Treat yourself to luxury during your St. Charles getaway by choosing a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and special one. Round-the-clock concierge assistance, elegant furnishings and gourmet dining are just the start of the first-rate services and conveniences you'll likely have access to.