A tropical island landscape with lush greenery and clear blue waters.

Compare and book 4 Star hotels in Colon, Colón

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Colon 4 Star Hotels

Our top choices for Colon 4-star hotels

Front of property

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,600 reviews)
"Nice hotel clean and large room very good breakfast I loved the pool and the polite staff"
Canada
naila
The price is £134
includes taxes & fees
3 Aug - 4 Aug
Megapolis Hotel Panamá
Front of property

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,006 reviews)
"Love the breakfast and the rooms were amazing"
United States
querube
The price is £135
includes taxes & fees
20 Aug - 21 Aug
Central Hotel Panama Casco Viejo
Daily buffet breakfast for a fee

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,004 reviews)
"Very nice stay, walking distance to Multi Plaza mall"
United States
Sergio
The price is £140
includes taxes & fees
3 Aug - 4 Aug
Sheraton Grand Panama
Exterior

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,009 reviews)
"Clean room, great staff, shops nearby."
United States
Lisandra
The price is £100
includes taxes & fees
25 Jul - 26 Jul
Courtyard by Marriott Panama Multiplaza Mall
Dining

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4.0 star property
Bella Vista
7.8 out of 10, Good, (1,007 reviews)
"My stay was amazing!!!!Breakfast was amazing!The staff were all amazing!❤️😊"
United States
Kikilia
The price is £102
includes taxes & fees
15 Aug - 16 Aug
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Outdoor pool

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,018 reviews)
"Great experience!!! Would definitely stay again."
United States
Stacian
The price is £76
includes taxes & fees
8 Aug - 9 Aug
Waymore Hotel Spa & Casino
Food and drink

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,009 reviews)
"Enjoyed my short stay"
United States
Chantelle
The price is £76
includes taxes & fees
15 Aug - 16 Aug
Courtyard by Marriott Panama Metromall
Front of property

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,711 reviews)
"Nice location"
United States
Yu Chih
The price is £75
includes taxes & fees
1 Aug - 2 Aug
Decapolis Hotel Panama City
Garden

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,003 reviews)
"The breakfast was very good. We love staying here"
United States
Patricia
The price is £70
includes taxes & fees
16 Aug - 17 Aug
Radisson Hotel Panama Canal
4 outdoor pools, open 8:00 AM to 8:00 PM, free pool cabanas

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.6 out of 10, Good, (1,030 reviews)
"The staff was very friendly and welcoming."
United States
Ariagner
The price is £229
includes taxes & fees
16 Aug - 17 Aug
Dreams Playa Bonita Panama - All Inclusive
Restaurant

Studio Coliving

Studio Coliving
4.5 star property
Bella Vista
7.8 out of 10, Good, (590 reviews)
"Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here"
United States
Phillip
Studio Coliving
View from property

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,054 reviews)
"Great location! Breakfast was good Overall nice stay"
United States
Mondisa
The price is £128
includes taxes & fees
1 Aug - 2 Aug
Las Americas Golden Tower Panama
Daily full breakfast for a fee

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (327 reviews)
"Beautifull hotel very attentive and nice staff breakfast is plussssss"
United States
hector
The price is £226
includes taxes & fees
27 Jul - 28 Jul
Hotel La Compañía Casco Antiguo
Exterior

Novotel Panama City

Novotel Panama City
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,245 reviews)
"I enjoyed my stay"
United States
Patrick
The price is £103
includes taxes & fees
4 Aug - 5 Aug
Novotel Panama City
Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1,004 reviews)
"The room was clean, the staff was nice and the breakfast had gluten free options, the gf bread was great and a really good buffet."
United States
Mara L
The price is £138
includes taxes & fees
8 Aug - 9 Aug
Marriott Panama Hotel
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, pool loungers

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (647 reviews)
"Everything was perfect, breakfast was good with many options and the fruits amazing, staff are very friendly and helpful, I really recommend this hotel."
United States
Frank David Delgado
The price is £168
includes taxes & fees
20 Aug - 21 Aug
Residence Inn by Marriott Panama City
Breakfast, lunch and dinner served

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,270 reviews)
"Great place to stay"
United States
Rafael
The price is £101
includes taxes & fees
30 Jul - 31 Jul
Ramada Plaza by Wyndham Panama Punta Pacifica
Outdoor pool

Hotel Dann Carlton Panamá

Hotel Dann Carlton Panamá
4.5 star property
Bella Vista
9.0 out of 10, Wonderful, (428 reviews)
"Well-maintained, good breakfast, helpful staff, good central location, free parking"
United States
Bettyanne
The price is £87
includes taxes & fees
20 Aug - 21 Aug
Hotel Dann Carlton Panamá
50-inch LED TV with satellite channels

Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.4 out of 10, Exceptional, (322 reviews)
"This is a great stay , property is very quiet and peaceful highly recommend"
United States
kenron
The price is £122
includes taxes & fees
25 Jul - 26 Jul
Corporate Stays Arcadia | Executive Furnished Apartments
Breakfast, lunch, dinner and brunch served

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (774 reviews)
"Everybody was so nice and attentive ! Location is great. It was our first time in Panama and it was just great !"
United States
Lourdes
The price is £165
includes taxes & fees
16 Aug - 17 Aug
American Trade Hotel
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Colon.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
The price is £123 per night from 31 Jul to 1 Aug
£123
31 Jul - 1 Aug
includes taxes & fees
Still don't see what you're looking for?
See all properties in Colon.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Colon

Explore the colourful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

See all hotels in Colon
A coastal archaeological site with ruins and a clear view of the ocean with boats.

Top Colon Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Excellent location at Plaza Independencia."
Freddy 4-night trip
Posted 1 hour ago
Central Hotel Panama Casco Viejo

Find out more about Colon

Frequently asked questions

What are the best 4-star hotels in Colon?
If you're looking for upscale comfort and loads of amenities on your Colon getaway, check out Radisson Colon 2,000 Hotel & Casino. This popular 4-star hotel offers proposal/romance packages and premium bedding. Melia Panama Canal also gets top reviews from Expedia customers. A terrace and a swimming pool are among its conveniences.
How much does it cost to stay in a 4-star hotel in Colon?
To lock in a 4-star hotel in Colon that's within your budget, take advantage of Expedia's filter tool. Take a look at what's available during your preferred dates and use our pricing filter to set your maximum rate. You can also list your results by the cheapest escape first.

  • Search for the lowest price from £123

What's the difference between 5-star and 4-star hotels in Colon?
Offering a welcoming traveller experience and upscale décor, 4-star hotels are a fantastic option for your Colon holiday. These types of stays generally feature lots of handy amenities that make it simple to unpack and recharge — think pillowtop mattresses, gyms and restaurants. Or live in the lap of luxury at a 5-star hotel designed to spoil you with luxury perks and amenities. On-site health clubs, complimentary toiletries and gourmet dining are typically featured at these swanky retreats.