
Luxury South America Holidays & Travel
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Top flight + Luxury hotel deals in South America

Hotel Boutique Casa del Coliseo
Reviewed on 14 Jul 2025


Hotel Casa San Agustin
Reviewed on 14 Jul 2025

Ananda Hotel Boutique
Reviewed on 10 Jul 2025

Country Club Lima Hotel - The Leading Hotels of the World
Reviewed on 18 Jul 2025
5* Luxury holidays in South America

Miramar by Windsor Copacabana
Reviewed on 19 Jul 2025


Country Club Lima Hotel - The Leading Hotels of the World
Reviewed on 18 Jul 2025
4 Night Luxury holidays in South America

Hotel Boutique Casa del Coliseo
Reviewed on 14 Jul 2025

Ananda Hotel Boutique
Reviewed on 10 Jul 2025

Bastión Luxury Hotel
Reviewed on 7 Jul 2025
All you need to know about luxury holidays in South America
What can I expect from a luxury South America holiday?
Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.
How can I find all-inclusive luxury holidays in South America?
Tick the all-inclusive and 5-star filters to find the crème de la crème of South America holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.
Can I book a cheap luxury holiday to South America?
A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to South America starting at £212. Prices and availability are subject to change. Additional terms may apply.
Are there luxury spa holidays in South America?
For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal South America spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.
What should I look for when booking a luxury family holiday in South America?
Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.
Can I book luxury last-minute holidays to South America?
You can wangle a top-notch luxury holiday in South America for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!
Can I book a luxury holiday in South America with free cancellation and/or flexible dates?
If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.
Why should I book my luxury travel to South America with Expedia?
Nobody does luxury quite like Expedia. With so many gorgeous properties in South America to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.
Top Luxury South America Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Reviewed on 6 Jul 2025

Hotel Club Frances
Reviewed on 24 Mar 2025

Palacio del Inka, A Luxury Collection Hotel by Marriott
Reviewed on 16 Jul 2025
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.