Luxury South America Holidays & Travel
Book a Luxury Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to £335 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Packages with flights are ATOL protected
Top flight + Luxury hotel deals in South America
Price found within the past 48 hours. Click for updated prices.
InterContinental Cartagena De Indias by IHG
Bocagrande
Price was £353, price is now £258 per person
£258
per person
21 Nov - 24 Nov
found 1 day ago
Additional charges may apply
Return flight included
Bogotá (BOG) to Cartagena (CTG)
9.4/10 Exceptional! (1,190 reviews)
more variety in food
Reviewed on 25 Aug 2025
Charleston Santa Teresa Cartagena
Cartagena Walled City
Save 100% on your flight
Price was £676, price is now £401 per person
£401
per person
21 Nov - 24 Nov
found 1 day ago
Additional charges may apply
Return flight included
Bogotá (BOG) to Cartagena (CTG)
9.4/10 Exceptional! (735 reviews)
We loved, loved, loved our stay at the Charlston Santa Teresa in Cartagena. We were greeted with elegance, cleanliness, and very friendly and honest staff, who were professional by the highest standards, and also looked out for our well being and safety. And that is something that no money can buy! Beyond that, there are the usual amenities like a gym, a pool, a nice restaurant, magnificent views (granite baths, beach proximity and city center not included - NOT kidding). The breakfast, too, was out of this world!
Reviewed on 21 Aug 2025
Bastión Luxury Hotel
Cartagena Walled City
Save 100% on your flight
Price was £581, price is now £354 per person
£354
per person
21 Nov - 24 Nov
found 1 day ago
Additional charges may apply
Return flight included
Bogotá (BOG) to Cartagena (CTG)
9.6/10 Exceptional! (1,004 reviews)
From the moment we walked through the doors of Bastión Luxury Hotel, we were treated with such warmth and kindness that it felt like coming home. Every single person we encountered—from the bellboys, reception, and restaurant staff to room service—went above and beyond to make our stay special.
What meant the most to me was how much love and care they showed my wife and my son. They weren’t just welcoming us as guests, they made us feel like family. Whether it was a friendly smile, remembering little details, or simply making sure we were always comfortable, their attention and thoughtfulness touched us deeply.
Cartagena is beautiful on its own, but the people at Bastión Luxury Hotel are what truly made our trip unforgettable. We left with full hearts, grateful for the memories we made and the kindness we experienced. This is not just a hotel—it’s a place where you feel seen, cared for, and truly at home.
Reviewed on 21 Aug 2025
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Price was £837, price is now £733 per person
£733
per person
30 Oct - 1 Nov
found 10 hours ago
Return direct flight included
Rio de Janeiro (GIG) to Iguassu Falls (IGU)
9.8/10 Exceptional! (1,005 reviews)
Fantastic hotel in a unique location. We had a wonderful stay - the setting is incredible & the staff are very attentive with attention to detail. Highly recommended.
Reviewed on 16 Aug 2025
Buenos Aires Marriott
El Centro
Price was £972, price is now £875 per person
£875
per person
14 Oct - 18 Oct
found 1 day ago
Return direct flight included
Miami (MIA) to Buenos Aires (BUE)
8.2/10 Very Good! (709 reviews)
Impresionante hotel. Siempre quise hospedarme ahi, por la ubicacion, pero despues de experimentar todo lo que ofrecen, son mas que solo ubicacion. Servicio, el aroma en todos los sectores, el spa, la piscina en el ultimo piso, sauna, personal… Buenos Aires tiene mucho para ofrecer en hoteleria, pero este lo recomiendo 100%!
Reviewed on 7 Aug 2025
Don't see what you're looking for?
See all available trips from Bogotá to South America
View all trips5* Luxury holidays in South America
Price found within the past 48 hours. Click for updated prices.
Charleston Santa Teresa Cartagena
Cartagena Walled City
Save 100% on your flight
Price was £676, price is now £401 per person
£401
per person
21 Nov - 24 Nov
found 1 day ago
Additional charges may apply
Return flight included
Bogotá (BOG) to Cartagena (CTG)
9.4/10 Exceptional! (735 reviews)
We loved, loved, loved our stay at the Charlston Santa Teresa in Cartagena. We were greeted with elegance, cleanliness, and very friendly and honest staff, who were professional by the highest standards, and also looked out for our well being and safety. And that is something that no money can buy! Beyond that, there are the usual amenities like a gym, a pool, a nice restaurant, magnificent views (granite baths, beach proximity and city center not included - NOT kidding). The breakfast, too, was out of this world!
Reviewed on 21 Aug 2025
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Price was £837, price is now £733 per person
£733
per person
30 Oct - 1 Nov
found 10 hours ago
Return direct flight included
Rio de Janeiro (GIG) to Iguassu Falls (IGU)
9.8/10 Exceptional! (1,005 reviews)
Fantastic hotel in a unique location. We had a wonderful stay - the setting is incredible & the staff are very attentive with attention to detail. Highly recommended.
Reviewed on 16 Aug 2025
Miramar by Windsor Copacabana
Copacabana
Price was £1,221, price is now £1,147 per person
£1,147
per person
14 Nov - 20 Nov
found 1 day ago
Return direct flight included
Norwich (NWI) to Rio de Janeiro (RIO)
9.6/10 Exceptional! (1,201 reviews)
Everything was perfect! Staff super friendly and amazing food.
Reviewed on 24 Aug 2025
Don't see what you're looking for?
See all available trips from Bogotá to South America
View all trips3 Night Luxury holidays in South America
Price found within the past 48 hours. Click for updated prices.
InterContinental Cartagena De Indias by IHG
Bocagrande
Price was £353, price is now £258 per person
£258
per person
21 Nov - 24 Nov
found 1 day ago
Additional charges may apply
Return flight included
Bogotá (BOG) to Cartagena (CTG)
9.4/10 Exceptional! (1,190 reviews)
more variety in food
Reviewed on 25 Aug 2025
Charleston Santa Teresa Cartagena
Cartagena Walled City
Save 100% on your flight
Price was £676, price is now £401 per person
£401
per person
21 Nov - 24 Nov
found 1 day ago
Additional charges may apply
Return flight included
Bogotá (BOG) to Cartagena (CTG)
9.4/10 Exceptional! (735 reviews)
We loved, loved, loved our stay at the Charlston Santa Teresa in Cartagena. We were greeted with elegance, cleanliness, and very friendly and honest staff, who were professional by the highest standards, and also looked out for our well being and safety. And that is something that no money can buy! Beyond that, there are the usual amenities like a gym, a pool, a nice restaurant, magnificent views (granite baths, beach proximity and city center not included - NOT kidding). The breakfast, too, was out of this world!
Reviewed on 21 Aug 2025
Bastión Luxury Hotel
Cartagena Walled City
Save 100% on your flight
Price was £581, price is now £354 per person
£354
per person
21 Nov - 24 Nov
found 1 day ago
Additional charges may apply
Return flight included
Bogotá (BOG) to Cartagena (CTG)
9.6/10 Exceptional! (1,004 reviews)
From the moment we walked through the doors of Bastión Luxury Hotel, we were treated with such warmth and kindness that it felt like coming home. Every single person we encountered—from the bellboys, reception, and restaurant staff to room service—went above and beyond to make our stay special.
What meant the most to me was how much love and care they showed my wife and my son. They weren’t just welcoming us as guests, they made us feel like family. Whether it was a friendly smile, remembering little details, or simply making sure we were always comfortable, their attention and thoughtfulness touched us deeply.
Cartagena is beautiful on its own, but the people at Bastión Luxury Hotel are what truly made our trip unforgettable. We left with full hearts, grateful for the memories we made and the kindness we experienced. This is not just a hotel—it’s a place where you feel seen, cared for, and truly at home.
Reviewed on 21 Aug 2025
Don't see what you're looking for?
See all available trips from Bogotá to South America
View all trips4 Night Luxury holidays in South America
Price found within the past 48 hours. Click for updated prices.
Sheraton Buenos Aires Hotel and Convention Center
El Centro
Price was £824, price is now £824 per person
£824
per person
14 Oct - 18 Oct
found 1 day ago
Return direct flight included
Miami (MIA) to Buenos Aires (BUE)
8.2/10 Very Good! (850 reviews)
El servicio fue excelente de tosoanloa integrandea del hotel
Reviewed on 17 Jul 2025
Buenos Aires Marriott
El Centro
Price was £972, price is now £875 per person
£875
per person
14 Oct - 18 Oct
found 1 day ago
Return direct flight included
Miami (MIA) to Buenos Aires (BUE)
8.2/10 Very Good! (709 reviews)
Impresionante hotel. Siempre quise hospedarme ahi, por la ubicacion, pero despues de experimentar todo lo que ofrecen, son mas que solo ubicacion. Servicio, el aroma en todos los sectores, el spa, la piscina en el ultimo piso, sauna, personal… Buenos Aires tiene mucho para ofrecer en hoteleria, pero este lo recomiendo 100%!
Reviewed on 7 Aug 2025
Park Tower, a Luxury Collection Hotel, Buenos Aires
El Centro
Price was £1,100, price is now £1,100 per person
£1,100
per person
14 Oct - 18 Oct
found 1 day ago
Return direct flight included
Miami (MIA) to Buenos Aires (BUE)
9.2/10 Wonderful! (436 reviews)
Very limited meat options at breakfast. Hotel rooms are probably becoming due for an overall upgrade. Lobby is lovely and employees are great.
Reviewed on 7 Aug 2025
All you need to know about luxury holidays in South America
What can I expect from a luxury South America holiday?
Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.
How can I find all-inclusive luxury holidays in South America?
Tick the all-inclusive and 5-star filters to find the crème de la crème of South America holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.
Can I book a cheap luxury holiday to South America?
A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to South America starting at £258. Prices and availability are subject to change. Additional terms may apply.
Are there luxury spa holidays in South America?
For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal South America spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.
What should I look for when booking a luxury family holiday in South America?
Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.
Can I book luxury last-minute holidays to South America?
You can wangle a top-notch luxury holiday in South America for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!
Can I book a luxury holiday in South America with free cancellation and/or flexible dates?
If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.
Why should I book my luxury travel to South America with Expedia?
Nobody does luxury quite like Expedia. With so many gorgeous properties in South America to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.
Top Luxury South America Hotels
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR
The price is £584 per night from 28 Aug to 29 Aug
£584
28 Aug - 29 Aug
includes taxes & fees
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (1,002 reviews)
World class perfection.
"One of the finest hotels in the world and the best hotel that I have ever stayed at. Exquisite attention to detail. The staff go out of their way to make sure everything you wish for is done. They are kind, attentive, and courteous without being overbearing. Just a remarkable experience. Everything ..."
Reviewed on 17 Aug 2025
Hotel Club Frances
Rodríguez Peña 1832, Buenos Aires, Capital Federal
The price is £122 per night from 27 Aug to 28 Aug
£122
27 Aug - 28 Aug
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff in their reviews. ...
Palacio del Inka, A Luxury Collection Hotel by Marriott
Plazoleta Santo Domingo No 259, Cusco, Cusco
The price is £295 per night from 27 Aug to 28 Aug
£295
27 Aug - 28 Aug
Stay at this 5-star luxury hotel in Cusco. Enjoy a full-service spa, room service and a fitness centre. Our guests praise the helpful staff in their reviews. ...
9.4/10 Exceptional! (927 reviews)
"Gorgeous hotel, very helpful staff, amazing location. I would definitely come back."
Reviewed on 24 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More holidays you might like
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.