Luxury South America Holidays & Travel

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Top flight + Luxury hotel deals in South America

Price found within the past 48 hours. Click for updated prices.
Hilton Barra Rio De Janeiro
Miramar by Windsor Copacabana
The Singular Santiago
The Westin Lima Hotel & Convention Center
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5* Luxury holidays in South America

Price found within the past 48 hours. Click for updated prices.
Miramar by Windsor Copacabana
The Singular Santiago
The Westin Lima Hotel & Convention Center
Don't see what you're looking for?
See all available trips from London to South America
View all trips

All you need to know about luxury holidays in South America

What can I expect from a luxury South America holiday?

Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.

How can I find all-inclusive luxury holidays in South America?

Tick the all-inclusive and 5-star filters to find the crème de la crème of South America holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.

Can I book a cheap luxury holiday to South America?

A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to South America starting at £1,212. Prices and availability are subject to change. Additional terms may apply.

Are there luxury spa holidays in South America?

For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal South America spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.

What should I look for when booking a luxury family holiday in South America?

Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.

Can I book luxury last-minute holidays to South America?

You can wangle a top-notch luxury holiday in South America for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!

Can I book a luxury holiday in South America with free cancellation and/or flexible dates?

If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.

Why should I book my luxury travel to South America with Expedia?

Nobody does luxury quite like Expedia. With so many gorgeous properties in South America to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.

Top Luxury South America Hotels

Hotel Club Frances
Hotel Club Frances
4.5 out of 5
Rodríguez Peña 1832, Buenos Aires, Capital Federal
The price is £182 per night from 23 May to 24 May
£182
per night
23 May - 24 May
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (593 reviews)
"Beautiful historic hotel, a lot of character, located at the best area of Buenos Aires, walkable to many landmarks"

Reviewed on 17 Apr 2024

Hotel Club Frances
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
5 out of 5
Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR
The price is £549 per night from 3 Jun to 4 Jun
£549
per night
3 Jun - 4 Jun
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the breakfast and the restaurant ...
9.8/10 Exceptional! (999 reviews)
"This may have been the best hotel experience in my life. Absolutely top-notch and superior in every way!"

Reviewed on 14 May 2024

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Palacio del Inka, A Luxury Collection Hotel by Marriott
Palacio del Inka, A Luxury Collection Hotel by Marriott
5 out of 5
Plazoleta Santo Domingo No 259, Cusco, Cusco
The price is £304 per night from 3 Jun to 4 Jun
£304
per night
3 Jun - 4 Jun
Stay at this 5-star luxury hotel in Cusco. Enjoy a full-service spa, room service and a fitness centre. Popular attractions Plaza de Armas and San Pedro Market ...
9.4/10 Exceptional! (769 reviews)
"Fantastic hotel with every amenity you would hope for. The rooms are spacious and include all toiletries. Convenient for walking. The restaurant is top notch. Highly recommend staying here if you like comfort and convenience. -and the art is great too!"

Reviewed on 18 May 2024

Palacio del Inka, A Luxury Collection Hotel by Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.