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South America Cheap Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Top Cheap holiday packages in South America

Price found within the past 48 hours. Click for updated prices.
  • 27 Dec - 31 Dec

    HAB Hotel + Flight

    Chapinero
    3 nights
    4.0 star property
    9.2/10 - Wonderful (653 reviews)
    Return • London (LON) - Bogotá (BOG)
    LHR - MDE • 1 stop MDE - LHR • 1 stop
    £1,473
    £1,421
    per traveller
    found 8 hours agoAdditional charges may apply
    HAB Hotel
  • 14 Dec - 19 Dec

    Sleep Inn Guarulhos + Flight

    Taboão
    5 nights
    3.0 star property
    8.2/10 - Very good (1,711 reviews)
    Return • London (LHR) - São Paulo (GRU)
    LHR - GRU • 1 stop GRU - LHR • Direct
    £2,861
    £2,779
    per traveller
    found 9 hours ago
    Sleep Inn Guarulhos
  • 14 Dec - 19 Dec

    Hotel Domani + Flight

    Guarulhos City Centre
    5 nights
    3.0 star property
    9.0/10 - Wonderful (1,477 reviews)
    Return • London (LHR) - São Paulo (GRU)
    LHR - GRU • 1 stop GRU - LHR • Direct
    £2,862
    £2,788
    per traveller
    found 9 hours ago
    Hotel Domani
  • 14 Dec - 19 Dec

    Hotel Dan Inn Planalto São Paulo by Nacional Inn + Flight

    República
    5 nights
    3.0 star property
    8.8/10 - Excellent (1,702 reviews)
    "Es un hotel antiguo que me sirvió para lo que buscaba que era dormir una noche allí. Incluye el desayuno. Creo que para el precio no se puede exigir mucho. El personal excelente y muy servicial."
    Reviewed October 28, 2026
    Return • London (LHR) - São Paulo (GRU)
    LHR - GRU • 1 stop GRU - LHR • Direct
    £2,769
    £2,712
    per traveller
    found 9 hours ago
    Hotel Dan Inn Planalto São Paulo by Nacional Inn
  • 14 Dec - 19 Dec

    Hampton by Hilton Guarulhos Airport + Flight

    Taboão
    5 nights
    4.0 star property
    8.8/10 - Excellent (2,803 reviews)
    "Este hotel mejoró 1.000%. Excelente!!!"
    Reviewed November 6, 2026
    Return • London (LHR) - São Paulo (GRU)
    LHR - GRU • 1 stop GRU - LHR • Direct
    £2,841
    £2,829
    per traveller
    found 9 hours ago
    Hampton by Hilton Guarulhos Airport

Discover the most popular places to visit in South America

Top Cheap South America Hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

Why should I book my South America holiday with Expedia?

Choose Expedia to organise your next break simply and all in the same place. Our insider tip for getting the best deal on a South America retreat? Bundle your accommodation, airfares and/or car hire into a package holiday. Then throw in some exciting tours and activities. Many bookings also come with flexible cancellation policies, so there's no need to stress if you have to switch up your travel itinerary. Round-the-clock help with making tweaks to your trip is available via our Customer Service Portal link.

How do I get a cheap holiday to South America?

Browse and lock in everything in the one place with our South America holidays. You'll discover deals on flights, hotels and more that'll keep your hip pocket happy and your adventurous spirit alive. And, with more than 400 air carriers and 321,000 hotels globally to pick from, you'll have the flexibility to mix and match as you please. Learn more about how you can save money on your next holiday when you combine your flight and hotel bookings with Expedia.

Do I need a visa for my South America holiday?

Official government websites will have all the information you need on visa requirements, application procedures and any supporting documentation. Your nationality and the purpose of your visit, whether it be for tourism or business, will determine if you need a visa for South America. Also double-check that your passport is up to date and has a minimum of six months validity remaining beyond your intended return date. Do all your travel planning well in advance to avoid any nasty last-minute surprises.

What should I wear on my South America holiday?

Do a little research into the sorts of things people in South America wear, and consider browsing style blogs for some fashion inspiration. Try to create a versatile travel wardrobe filled with pieces that suit your destination and show off your unique sense of style.

What does an Expedia South America holiday include?

It comes down to what type of trip you have in mind. South America travel deals can include hotels, car hires and flights. You can mix and match to find the bundle that suits your style and budget. You can also add on activities and experiences after you've booked to pick up even bigger discounts. You'll always have the flexibility and freedom to tailor-make your holiday any way you please with Expedia.

Does Expedia offer Book Now, Pay Later South America holidays?

Your bank balance shouldn't prevent you from taking a holiday, so Expedia has come up with a solution to help. Now that we've partnered with online lender Klarna, it's easier than ever to book a fabulous getaway without making a dent in your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your trip. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's manageable instalment plans. If paying in multiple instalments sounds right for you, choose this option at checkout.
  • No-deposit holidays: When you want to jump on an unbeatable deal but your budget doesn't quite cover it yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to get what you want.

Can I choose my airline with a South America Expedia holiday?

With a holiday package, the choice is in your hands. Whether you're looking to fly to South America in first class or coach, simply select from the available airline options. Expedia has access to over 400 partner airlines globally.