Florida Keys Adults Only Holidays

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    Save up to £750 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Packages with flights are ATOL protected

Top flight + Adults Only hotel deals in Florida Keys

Price found within the past 48 hours. Click for updated prices.
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

£1,036
per person
1 Nov - 6 Nov
found 10 hours ago
Return flight included
London (LON) to Miami (MIA)
8.8/10 Excellent! (1,008 reviews)
Toda la instalación está en muy buenas condiciones y limpia , la atención del staff es super buena y realmente se pasa muy bien y tranquilo

Reviewed on 17 Aug 2026

Cheeca Lodge & Spa

Cheeca Lodge & Spa

Matecumbe
£1,237
per person
1 Nov - 6 Nov
found 10 hours ago
Return flight included
London (LON) to Miami (MIA)
9.2/10 Wonderful! (1,360 reviews)
Hawks Cay Resort

Hawks Cay Resort

£1,320
per person
1 Nov - 6 Nov
found 10 hours ago
Return flight included
London (LON) to Miami (MIA)
8.2/10 Very good! (1,009 reviews)
So relaxing now need to do anything but relax

Reviewed on 18 Aug 2026

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

Old Town Key West
£1,342
per person
1 Nov - 6 Nov
found 10 hours ago
Return flight included
London (LON) to Key West (EYW)
8.8/10 Excellent! (3,469 reviews)
Super clean room! So many things to do- pool, beach, restaurants!! Staff was super awesome and friendly. We loved it!!!

Reviewed on 19 Aug 2026

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

£1,285
per person
1 Nov - 6 Nov
found 10 hours ago
Return flight included
London (LON) to Miami (MIA)
8.6/10 Excellent! (1,160 reviews)
Recommend!

Reviewed on 18 Aug 2026

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5* Adults Only holidays in Florida Keys

Price found within the past 48 hours. Click for updated prices.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

Matecumbe
£1,237
per person
1 Nov - 6 Nov
found 10 hours ago
Return flight included
London (LON) to Miami (MIA)
9.2/10 Wonderful! (1,360 reviews)
Don't see what you're looking for?
See all available trips from London to Florida Keys
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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

525 United Street Key West FL
  • 9 min walk from Duval Street
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8.4/10 Very good! (1,427 reviews)
"I traveled solo and stayed in the Attic Room. The room I stayed in is bigger than it looks in the pictures. There is a small private bathroom with shower stall. The room doesn't get super cold but the AC keeps it comfortable. (I think a table fan would be a great addition to the room) There is a ..."

Reviewed on 18 Aug 2026

The Southernmost Inn - Adults Only
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL
  • 4 min walk from Duval Street
Stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge) and a garden. Our guests praise the breakfast and the pool in their ...
Paradise Inn Key West - Adults Only
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St Key West FL
  • 3 min walk from Duval Street
Stay at this B&B in Key West. Enjoy free breakfast, free Wi-Fi and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...
Heron House - Adult Only
See all 8,304 properties in Florida Keys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

Aerial view of people snorkeling in Key West

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

£34
per adult
94% of travellers recommend
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Snorkler waving underwater in Key West

Key West Coral Reef Snorkel with Mimosas, Margaritas or Rum Punch

£46
per adult
86% of travellers recommend
Key West Coral Reef Snorkel with Mimosas, Margaritas or Rum Punch
Key West Premium Sunset Sail with Champagne, Wine & Tapas

Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar

£59
per adult
94% of travellers recommend
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
See all activities in Florida Keys

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.