Florida Keys Adults Only Holidays

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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

525 United Street Key West FL
  • 9 min walk from Duval Street
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8.4/10 Very good! (1,427 reviews)
"I traveled solo and stayed in the Attic Room. The room I stayed in is bigger than it looks in the pictures. There is a small private bathroom with shower stall. The room doesn't get super cold but the AC keeps it comfortable. (I think a table fan would be a great addition to the room) There is a ..."

Reviewed on 18 Aug 2026

The Southernmost Inn - Adults Only
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL
  • 4 min walk from Duval Street
Stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge) and a garden. Our guests praise the breakfast and the pool in their ...
Paradise Inn Key West - Adults Only
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St Key West FL
  • 3 min walk from Duval Street
Stay at this B&B in Key West. Enjoy free breakfast, free Wi-Fi and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...
Heron House - Adult Only
See all 8,304 properties in Florida Keys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

Aerial view of people snorkeling in Key West

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

£34
per adult
94% of travellers recommend
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Snorkler waving underwater in Key West

Key West Coral Reef Snorkel with Mimosas, Margaritas or Rum Punch

£46
per adult
86% of travellers recommend
Key West Coral Reef Snorkel with Mimosas, Margaritas or Rum Punch
Key West Premium Sunset Sail with Champagne, Wine & Tapas

Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar

£59
per adult
94% of travellers recommend
Dolphin Watch Catamaran Sunset Sail w/ Tapas and Open Bar
See all activities in Florida Keys

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.