
South America Adults Only Holidays
Book a Adults Only Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top flight + Adults Only hotel deals in South America
Price found within the past 48 hours. Click for updated prices.

Casa del Arzobispado Hotel
Cartagena Walled City
Price was £1,168, price is now £822 per person
£822
per person
17 Dec - 20 Dec
found 20 hours ago
Additional charges may apply
Return flight included
Miami (MIA) to Cartagena (CTG)
9.4/10 Exceptional! (360 reviews)
Stay was amazing, staff was super helpful and friendly. Felt like home away from home. I’m defintely looking forward to booking this hotel again on my next visit. Was the perfect location inside the Walled City.
Reviewed on 23 Oct 2026
3 Night Adults Only holidays in South America
Price found within the past 48 hours. Click for updated prices.

Casa del Arzobispado Hotel
Cartagena Walled City
Price was £1,168, price is now £822 per person
£822
per person
17 Dec - 20 Dec
found 20 hours ago
Additional charges may apply
Return flight included
Miami (MIA) to Cartagena (CTG)
9.4/10 Exceptional! (360 reviews)
Stay was amazing, staff was super helpful and friendly. Felt like home away from home. I’m defintely looking forward to booking this hotel again on my next visit. Was the perfect location inside the Walled City.
Reviewed on 23 Oct 2026
Top Adults Only South America Hotels

Hotel Nirvana
Paseo de la Republica 6315 Lima Lima
Stay at this hotel in Lima. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Larcomar Shopping Center and John F. Kennedy Park are located ...
6.6/10 (13 reviews)
"Inexpensive and clean, little to no hot water in bathroom."
Reviewed on 7 Sept 2018

84 DC Bogotá By OxoHotel
Calle 84 No 9-67 Bogotá Distrito Capital
The price is £62 per night from 14 Nov to 15 Nov
£62
14 Nov - 15 Nov
additional charges may apply
Stay at this business-friendly hotel in Bogotá. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (720 reviews)
"Cleanliness Cozy Comfortable Smart Service Helpful Staff Excellent"
Reviewed on 30 Oct 2026

Alfiz Hotel Boutique
Calle Cochera del Gobernador, 33-28 Cartagena Bolivar
Stay at this historic hotel in Cartagena. Enjoy free breakfast, free Wi-Fi and a rooftop terrace. Our guests praise the helpful staff in their reviews. Popular ...
9.6/10 Exceptional! (199 reviews)
"Notch to really like but it did have a good location"
Reviewed on 10 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.










