
South Carolina Adults Only Holidays
Book a Adults Only Hotel + Flight or Car together to unlock savings
Better together
Save up to £335 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top flight + Adults Only hotel deals in South Carolina
Price found within the past 48 hours. Click for updated prices.

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
Save 100% on your flight
per person
17 Sept - 21 Sept
found 13 hours ago
Return direct flight included
Columbus (CMH) to Charleston (CHS)
8.8/10 Excellent! (1,003 reviews)
The valet staff were exceptional as the first point of contact at the resort. They were extremely helpful, ensuring guests were comfortable while waiting or being transported. They even offered water to help guests stay cool. Overall, it was a warm and welcoming experience that set a great tone for the visit.
Reviewed on 23 Jun 2025

Omni Hilton Head Oceanfront Resort
Mid Island
per person
4 Sept - 8 Sept
found 1 day ago
Return direct flight included
Edinburgh (EDI) to Savannah (SAV)
9/10 Wonderful! (1,005 reviews)
Fantastic options for Families. Rooms were big, the kitchenette with sink & microwave allowed for some quick & easy meals for our young children. Resort is large, with plenty of room, the staff is friendly & attentive. An overall great option. The only negative is we didn’t have a bathtub for our 2 year old.
Reviewed on 12 Jul 2025

86 Cannon Charleston - Adults Only
Downtown Charleston
Save 100% on your flight
per person
17 Sept - 21 Sept
found 1 day ago
Return flight included
Atlanta (ATL) to Charleston (CHS)
10/10 Exceptional! (69 reviews)
Beautiful setting, excellent staff, and walkable to King Street and surrounding area.
Reviewed on 12 May 2025
Don't see what you're looking for?
See all available trips from Columbus to South Carolina
View all trips4 Night Adults Only holidays in South Carolina
Price found within the past 48 hours. Click for updated prices.

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
Save 100% on your flight
per person
17 Sept - 21 Sept
found 13 hours ago
Return direct flight included
Columbus (CMH) to Charleston (CHS)
8.8/10 Excellent! (1,003 reviews)
The valet staff were exceptional as the first point of contact at the resort. They were extremely helpful, ensuring guests were comfortable while waiting or being transported. They even offered water to help guests stay cool. Overall, it was a warm and welcoming experience that set a great tone for the visit.
Reviewed on 23 Jun 2025

Omni Hilton Head Oceanfront Resort
Mid Island
per person
4 Sept - 8 Sept
found 1 day ago
Return direct flight included
Edinburgh (EDI) to Savannah (SAV)
9/10 Wonderful! (1,005 reviews)
Fantastic options for Families. Rooms were big, the kitchenette with sink & microwave allowed for some quick & easy meals for our young children. Resort is large, with plenty of room, the staff is friendly & attentive. An overall great option. The only negative is we didn’t have a bathtub for our 2 year old.
Reviewed on 12 Jul 2025
Don't see what you're looking for?
See all available trips from Columbus to South Carolina
View all tripsTop Adults Only South Carolina Hotels

86 Cannon Charleston - Adults Only
86 Cannon Street, Charleston, SC
The price is £390 per night from 16 Jul to 17 Jul
£390
16 Jul - 17 Jul
includes taxes & fees
Stay at this 4.5-star luxury inn in Charleston. Enjoy free breakfast, free Wi-Fi and free bicycles on-site. Popular attractions Port of Charleston Cruise Terminal ...
10/10 Exceptional! (69 reviews)
"Beautiful setting, excellent staff, and walkable to King Street and surrounding area."
Reviewed on 12 May 2025

Affordable Suites Myrtle Beach
117 W Perry Rd., Myrtle Beach, SC
Stay at this hotel in Myrtle Beach. Enjoy free Wi-Fi, free parking and laundry facilities. Popular attractions Broadway at the Beach and Coastal Grand Mall are ...
8.6/10 Excellent! (265 reviews)
Highly recommend
"We stayed for 2 nights for a wedding. The property was small, off the main road so it was nice and quiet. Nancy at the desk was beyond gracious and the room was very clean! We prefer a bit of a firm mattress to which we were pleased that we didn't sink into the mattress. We will definitely stay here ..."
Reviewed on 13 Jul 2025

Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd, Orangeburg, SC
The price is £54 per night from 16 Jul to 17 Jul
£54
16 Jul - 17 Jul
includes taxes & fees
Stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Smith-Hammond-Middleton Memorial Center ...
6/10 (1,006 reviews)
Ok but no pool
"It was ok. The pool is not open. Doesnt even looks like it's been in use"
Reviewed on 1 Jul 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More holidays you might like
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.