Title: £217 Cheap Flights from Knoxville to Manchester (TYS to MHT) - Expedia.co.uk ![Manchester showing a city](https://images.trvl-media.com/place/6025582/1742693d-d0f5-4136-9eae-16056794d131.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6025582/1742693d-d0f5-4136-9eae-16056794d131.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £217 Cheap Flights from Knoxville (TYS) to Manchester (MHT) [View £217 flight on Sat, 22 Nov 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:TYS,to:MHT,departure:22/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:216.60&airProductToken=AQpmCjEIwYIBEgQ1ODYxGJOWASDvWSjf5f0CMNTm_QI4TkAAWAFqBE1BSU5yCE5VQUlaTk4xCjEIwYIBEgQ1ODgwGO9ZIOyZASiR5_0CMO3n_QI4TkABWAFqBE1BSU5yCE5VQUlaTk4xEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Alcoa - Knoxville Airport (TYS) to Manchester-Boston Regional Airport (MHT) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:tys,to:mht,departure:09/11/2025TANYT&leg2=from:mht,to:tys,departure:16/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:tys,to:mht,departure:09/11/2025TANYT&leg2=from:mht,to:tys,departure:16/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:tys,to:mht,departure:09/11/2025TANYT&leg2=from:mht,to:tys,departure:16/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Knoxville (TYS) to Manchester (MHT) Prices were available within the past 7 days and start at £217 for one-way flights and £320 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, 24 Nov - Fri, 28 Nov TYS Knoxville MHT Manchester £320 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:24/11/2025TANYT&leg2=from:MHT,to:TYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:319.30&airProductToken=AQpGCiEI1YIBEgQ0MzI1GJOWASCIGCia-P0CMIH5_QI4TEAAWAEKIQjVggESBDQ5MzAYiBgg7JkBKKn5_QIwh_r9AjhMQAFYAQpGCiEI1YIBEgQ0ODU3GOyZASCIGCiGpf4CMPyl_gI4TEAAWAEKIQjVggESBDQzMDgYiBggk5YBKNOm_gIwv6f-AjhMQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, 19 Nov - Tue, 2 Dec TYS Knoxville MHT Manchester £333 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:19/11/2025TANYT&leg2=from:MHT,to:TYS,departure:02/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:332.20&airProductToken=AQpICiIIwYIBEgQ1OTk1GJOWASDimgEotMT9AjCIxf0COFFAAFgBCiIIwYIBEgQ1NjU1GOKaASDsmQEou8X9AjDAxv0COFFAAVgBCkQKIAjBggESBDU2MjMY7JkBIEMo3NX-AjDN1v4COFFAAFgBCiAIwYIBEgQ1NDg0GEMgk5YBKPDW_gIw2df-AjhRQAFYARIKCAEQARgBKgJBQRgBIgQIARABKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Wed, 19 Nov - Fri, 28 Nov TYS Knoxville MHT Manchester £335 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:19/11/2025TANYT&leg2=from:MHT,to:TYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:334.30&airProductToken=AQpGCiEI1YIBEgQ0MzI1GJOWASCIGCj6v_0CMOHA_QI4VEAAWAEKIQjVggESBDQ5MzAYiBgg7JkBKInB_QIw58H9AjhUQAFYAQpGCiEI1YIBEgQ0ODU3GOyZASCIGCiGpf4CMPyl_gI4TEAAWAEKIQjVggESBDQzMDgYiBggk5YBKNOm_gIwv6f-AjhMQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, 24 Nov - Tue, 2 Dec TYS Knoxville MHT Manchester £342 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:24/11/2025TANYT&leg2=from:MHT,to:TYS,departure:02/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:341.80&airProductToken=AQpGCiEI1YIBEgQ0MzI1GJOWASCIGCia-P0CMIH5_QI4TEAAWAEKIQjVggESBDQ5MzAYiBgg7JkBKKn5_QIwh_r9AjhMQAFYAQpGCiEI1YIBEgQ0ODI5GOyZASCIGCjb1v4CMNHX_gI4S0AAWAEKIQjVggESBDQyNTcYiBggk5YBKIjd_gIw9N3-AjhLQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, 24 Nov - Thu, 27 Nov TYS Knoxville MHT Manchester £346 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:24/11/2025TANYT&leg2=from:MHT,to:TYS,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:345.10&airProductToken=AQpECiAIwYIBEgQ1MTQ5GJOWASBDKMD2_QIwp_f9AjhPQABYAQogCMGCARIENTEzNRhDIOyZASiD_v0CMOr-_QI4T0ABWAEKRAogCMGCARIENTE2MBjsmQEgQyiUmP4CMIGZ_gI4UUAAWAEKIAjBggESBDUyMDcYQyCTlgEoxZn-AjC2mv4COFFAAVgBEgoIARABGAEqAkFBGAEiBAgBEAEoBDAB) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, 25 Nov - Fri, 28 Nov TYS Knoxville MHT Manchester £368 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:25/11/2025TANYT&leg2=from:MHT,to:TYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:367.60&airProductToken=AQpGCiEI1YIBEgQ0MzExGJOWASCIGCjFgf4CMKyC_gI4S0AAWAEKIQjVggESBDQ5MzAYiBgg7JkBKMmE_gIwp4X-AjhUQAFYAQpGCiEI1YIBEgQ0ODU3GOyZASCIGCiGpf4CMPyl_gI4TEAAWAEKIQjVggESBDQzMDgYiBggk5YBKNOm_gIwv6f-AjhMQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, 21 Nov - Tue, 2 Dec TYS Knoxville MHT Manchester £375 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:21/11/2025TANYT&leg2=from:MHT,to:TYS,departure:02/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:374.10&airProductToken=AQpGCiEIwYIBEgQ1MTk5GJOWASDvWSj61v0CMOzX_QI4TkAAWAEKIQjBggESBDU4MTAY71kg7JkBKK7Y_QIwhtn9AjhOQAFYAQpECiAIwYIBEgQ1NjIzGOyZASBDKNzV_gIwzdb-AjhRQABYAQogCMGCARIENTQ4NBhDIJOWASjw1v4CMNnX_gI4UUABWAESCggBEAEYASoCQUEYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, 21 Nov - Thu, 27 Nov TYS Knoxville MHT Manchester £376 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:21/11/2025TANYT&leg2=from:MHT,to:TYS,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:375.20&airProductToken=AQpGCiEIwYIBEgQ1MTk5GJOWASDvWSj61v0CMOzX_QI4TkAAWAEKIQjBggESBDU4MTAY71kg7JkBKK7Y_QIwhtn9AjhOQAFYAQpECiAIwYIBEgQ1MTYwGOyZASBDKJSY_gIwgZn-AjhRQABYAQogCMGCARIENTIwNxhDIJOWASjFmf4CMLaa_gI4UUABWAESCggBEAEYASoCQUEYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, 22 Nov - Tue, 2 Dec TYS Knoxville MHT Manchester £378 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:22/11/2025TANYT&leg2=from:MHT,to:TYS,departure:02/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:377.30&airProductToken=AQpGCiEIwYIBEgQ1ODYxGJOWASDvWSjf5f0CMNTm_QI4VkAAWAEKIQjBggESBDU4ODAY71kg7JkBKJHn_QIw7ef9AjhWQAFYAQpECiAIwYIBEgQ1NjIzGOyZASBDKNzV_gIwzdb-AjhRQABYAQogCMGCARIENTQ4NBhDIJOWASjw1v4CMNnX_gI4UUABWAESCggBEAEYASoCQUEYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, 22 Nov - Thu, 27 Nov TYS Knoxville MHT Manchester £379 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:22/11/2025TANYT&leg2=from:MHT,to:TYS,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:378.40&airProductToken=AQpGCiEIwYIBEgQ1ODYxGJOWASDvWSjf5f0CMNTm_QI4VkAAWAEKIQjBggESBDU4ODAY71kg7JkBKJHn_QIw7ef9AjhWQAFYAQpECiAIwYIBEgQ1MTYwGOyZASBDKJSY_gIwgZn-AjhRQABYAQogCMGCARIENTIwNxhDIJOWASjFmf4CMLaa_gI4UUABWAESCggBEAEYASoCQUEYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, 25 Nov - Tue, 2 Dec TYS Knoxville MHT Manchester £391 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:25/11/2025TANYT&leg2=from:MHT,to:TYS,departure:02/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:390.20&airProductToken=AQpGCiEI1YIBEgQ0MzExGJOWASCIGCjFgf4CMKyC_gI4S0AAWAEKIQjVggESBDQ5MzAYiBgg7JkBKMmE_gIwp4X-AjhUQAFYAQpGCiEI1YIBEgQ0ODI5GOyZASCIGCjb1v4CMNHX_gI4S0AAWAEKIQjVggESBDQyNTcYiBggk5YBKIjd_gIw9N3-AjhLQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Thu, 20 Nov - Fri, 28 Nov TYS Knoxville MHT Manchester £410 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:20/11/2025TANYT&leg2=from:MHT,to:TYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:409.60&airProductToken=AQpGCiEI1YIBEgQ0MzI1GJOWASCIGCiay_0CMIHM_QI4VkAAWAEKIQjVggESBDQ5MzAYiBgg7JkBKKnM_QIwh839AjhWQAFYAQpGCiEI1YIBEgQ0ODU3GOyZASCIGCiGpf4CMPyl_gI4TEAAWAEKIQjVggESBDQzMDgYiBggk5YBKNOm_gIwv6f-AjhMQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, 25 Nov - Thu, 27 Nov TYS Knoxville MHT Manchester £418 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:25/11/2025TANYT&leg2=from:MHT,to:TYS,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:417.10&airProductToken=AQpGCiEI1YIBEgQ0MzExGJOWASCIGCjFgf4CMKyC_gI4S0AAWAEKIQjVggESBDQ5MzAYiBgg7JkBKMmE_gIwp4X-AjhUQAFYAQpGCiEI1YIBEgQ0ODU3GOyZASCIGCjmmf4CMNya_gI4U0AAWAEKIQjVggESBDQzMDgYiBggk5YBKLOb_gIwn5z-AjhTQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Sun, 23 Nov - Fri, 28 Nov TYS Knoxville MHT Manchester £421 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TYS,to:MHT,departure:23/11/2025TANYT&leg2=from:MHT,to:TYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:420.30&airProductToken=AQpGCiEI1YIBEgQ0MzExGJOWASCIGCiF6_0CMOzr_QI4U0AAWAEKIQjVggESBDQ5MzIYiBgg7JkBKNny_QIwvPP9AjhUQAFYAQpGCiEI1YIBEgQ0ODU3GOyZASCIGCiGpf4CMPyl_gI4TEAAWAEKIQjVggESBDQzMDgYiBggk5YBKNOm_gIwv6f-AjhMQAFYARIKCAEQARgBKgJVQRgBIgQIARABKAQwAQ) ## Find the cheapest month to fly from Knoxville (TYS) to Manchester (MHT) ### September is typically the cheapest month to fly From £185 - £429 per traveller. Flight from Knoxville to Manchester route information | Origin airport | McGhee Tyson | | --- | --- | | Destination airport | Manchester-Boston Regional | | Return price | £319 | | Distance | 1328 km | ## Compare flights from Knoxville to Manchester easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Knoxville to Manchester. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Manchester-Boston Regional in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from McGhee Tyson to Manchester-Boston Regional.   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from McGhee Tyson (TYS) to Manchester-Boston Regional (MHT) The easiest way to view the best deals on flights from Knoxville to Manchester today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from McGhee Tyson to Manchester-Boston Regional start at just £320 and range up to £421.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Knoxville and Manchester - booking your flight during November, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Knoxville to Manchester flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from McGhee Tyson to Manchester-Boston Regional for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Frequently asked questions ### How much is a flight from McGhee Tyson Airport (TYS) to MHT? > If you're planning on travelling between Knoxville Airport and Manchester Airport, round-trip flights start from £320. This figure is based on fares listed within the last 7 days on Expedia for flights departing within the next year, so don't hang about. Book today and save yourself both money and time. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Knoxville Airport to MHT? > Every air carrier has its own terms and conditions. If you do decide to cancel, follow the simple instructions on our [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033). ### How do I find cheap flights from McGhee Tyson Airport (TYS) to Manchester Airport that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for McGhee Tyson Airport (TYS) to Manchester Airport flights, you'll see a "no change fees" filter for you to select. ### How many hours is the flight from Knoxville Airport to MHT? > The flight time from TYS to Manchester Airport is approximately 3 hours and 32 minutes. Put your earphones in, listen to your favourite tunes and the hours in the air will fly by. ### How far is the flight from TYS to Manchester-Boston Regional Airport (MHT)? > The flight distance from McGhee Tyson Airport (TYS) (TYS) to Manchester Airport (MHT) is 1,350 kilometres. You'll be disembarking the plane and collecting your bags from the carousel in the blink of an eye. ### Which airlines fly direct from McGhee Tyson Airport (TYS) to Manchester-Boston Regional Airport (MHT)? > If you want to travel straight from McGhee Tyson Airport (TYS) to Manchester-Boston Regional Airport (MHT), you'll need to book a flight with at least one stop. Unfortunately, there are no airlines that fly directly between these airports. ### Are TYS to Manchester Airport flight tickets cheaper when they're purchased at the last minute? > Flight tickets from TYS to MHT are available up to a year prior to departure on Expedia. And although you may score a fantastic last-minute deal, it's never something you can count on. Also, booking your flights ahead of time means you'll have more choices — and you can avoid getting caught in the dreaded middle seat! 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