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£303 Cheap Flights from San Francisco (SFO) to Southampton (SOU)

View £303 flight on Sun, 10 Jan 2027Opens in a new window

Popular airlines from San Francisco International Airport (SFO) to Southampton (SOU)

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Cheap Flights from San Francisco (SFO) to Southampton (SOU)

Prices were available within the past 7 days and start at £303 for one-way flights and £1,065 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,065 Return, found 1 day ago
£1,065
Return
found 1 day ago
Select KLM flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,065 found 1 day ago
KLM
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,065 Return, found 1 day ago
£1,065
Return
found 1 day ago
Select KLM flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,065 found 1 day ago
KLM
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,100 Return, found 1 day ago
£1,100
Return
found 1 day ago
Select KLM flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,100 found 1 day ago
KLM
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,100 Return, found 1 day ago
£1,100
Return
found 1 day ago
Select KLM flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,100 found 1 day ago
KLM
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,106 Return, found 1 day ago
£1,106
Return
found 1 day ago
Select KLM flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,106 found 1 day ago
KLM
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,127 Return, found 1 day ago
£1,127
Return
found 1 day ago
Select KLM flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,127 found 1 day ago
Virgin Atlantic
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,171 Return, found 1 day ago
£1,171
Return
found 1 day ago
Select Virgin Atlantic flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,171 found 1 day ago
Aer Lingus
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,197 Return, found 1 day ago
£1,197
Return
found 1 day ago
Select Aer Lingus flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,197 found 1 day ago
Finnair
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,200 Return, found 1 day ago
£1,200
Return
found 1 day ago
Select Finnair flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,200 found 1 day ago
Air Canada
Mon, 10 Aug - Fri, 14 Aug
SFO
San Francisco
SOU
Southampton
£1,217 Return, found 1 day ago
£1,217
Return
found 1 day ago
Select Air Canada flight, departing Mon, 10 Aug from San Francisco to Southampton, returning Fri, 14 Aug, priced at £1,217 found 1 day ago

Alternative airports near Southampton

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Southampton SOU. Cheapest and Closest option available. Average driving time to city centre is 10 minutes. Flights from £1,065
SOU
Southampton
CheapestClosest
Average driving time to city centre10 min
Flights from £1,065

Frequently asked questions

How much does a flight from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) cost?
You can find one-way and return flights from SFO to SOU with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when SFO to SOU ticket fares go up or down.
What is the cheapest month to fly from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
The cheapest months to fly from SFO to SOU are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
Enter SFO to SOU and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
American Airlines is one of the cheapest airlines offering connecting return flights from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU), with prices starting from around £776 for flights that can be booked for departure within the next year, with a layover in Dallas-Fort Worth Intl. (DFW). These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
To find a cheap flight from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
There are approximately 51 connecting flights per day from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU). Some common connection points include John F. Kennedy Intl. (JFK), Hartsfield-Jackson Atlanta Intl. (ATL), and O'Hare Intl. (ORD).
What is the earliest flight from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from SFO to SOU. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
You'll typically find the most flights from San Francisco Intl. (SFO) to Southampton (SOU) on a Wednesday, with around 65 flights available. This gives you a good selection of options for your journey. Major airlines on this route include Delta, American Airlines, and United.
What are the most popular departure times for flights from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
The most popular departure times for flights from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) are in the afternoon, from 3pm to 6pm. Many major carriers, including Aer Lingus, Air France and Delta, offer flights during this window. Many travellers prefer this timing because it allows for a full day of activities before heading to the airport, and you'll arrive at your destination ready to start your trip.
How long does it take to fly from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
There are no nonstop flights from San Francisco International Airport (SFO) to Southampton (SOU). The distance between these two locations is approximately 8616 kilometres (5354 miles). If you're flying with one stop, your journey will typically take around 15 hours 18 minutes. Flights with two or more stops usually take longer, averaging about 18 hours 48 minutes. Keep in mind that actual travel times can vary based on your specific routing, layover durations, and factors like wind patterns.
Can you fly business or first class from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
You can fly business class between SFO and SOU. You can fly business class with KLM and Delta.
How do I earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) flight with Expedia?
It's easy to earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Keyâ„¢, you can also earn OneKeyCashâ„¢* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
Is it cheaper to buy a plane ticket from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) at the last minute?
Typically, booking a last minute flight from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) flight and hotel package?
Securing a San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU)?
If you booked your San Francisco, CA (SFO-San Francisco Intl.) to Southampton (SOU) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
San Francisco Intl.
Destination airport
Southampton
Return price
£1,064
Distance
8564 km

Book with confidence

Compare flights from San Francisco to Southampton easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from San Francisco to Southampton. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Southampton in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from San Francisco Intl. to Southampton.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from San Francisco Intl. (SFO) to Southampton (SOU)

The easiest way to view the best deals on flights from San Francisco to Southampton today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from San Francisco Intl. to Southampton start at just £1,065 and range up to £1,217.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near San Francisco and Southampton
  • booking your flight during August, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your San Francisco to Southampton flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from San Francisco Intl. to Southampton for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from San Francisco to Southampton easily and book with confidence

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*Available to Expedia members.