Title: £325 Cheap Flights from Santiago to Houston (SCL to IAH) - Expedia.co.uk

 

![Downtown Houston, Texas, USA Drone Skyline Aerial Panorama](https://images.trvl-media.com/place/1503/aa95b363-6144-464c-8751-31ea747786d2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/1503/aa95b363-6144-464c-8751-31ea747786d2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# £325 Cheap Flights from Santiago (SCL) to Houston (IAH)

[View £325 flight on Mon, 3 Nov 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:SCL,to:IAH,departure:03/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:324.90&airProductToken=AQqXAQowCMGGARICOTMY0lggmM4BKJuQ_AIwoJX8AjhLQABYAWoFQkFTSUNyCEtMWlQxNkJBCjEIwYYBEgM0MTIYmM4BIJhdKNiY_AIwqpn8AjhLQAFYAWoFQkFTSUNyCEtMWlQxNkJBCjAIwYYBEgM1ODMYmF0giDgohJv8AjCbnfwCOEtAAVgBagVCQVNJQ3IIS0xaVDE2QkESCggBEAEYASoCQUMYASIECAEQASgCKAMoBDAB)

-   [Return](?flightType=roundtrip)
-   [One-way](?flightType=oneway)
-   [Multi-city](?flightType=multicity)

### Travellers

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

EconomyPremium economyBusiness classFirst class

Leaving from

Going to

Departing

Returning

Add a place to stay

Add a car

Direct flights only

## Popular airlines from Santiago Intl. Airport (SCL) to George Bush Intercontinental Airport (IAH)

-   ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg)
    
    Avianca
    
    [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:iah,departure:15/11/2025TANYT&leg2=from:iah,to:scl,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}])
-   ![Air Canada](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AC.svg)
    
    Air Canada
    
    [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:iah,departure:15/11/2025TANYT&leg2=from:iah,to:scl,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AC"}}])
-   ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg)
    
    Delta
    
    [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:iah,departure:15/11/2025TANYT&leg2=from:iah,to:scl,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}])
-   ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg)
    
    United
    
    [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:iah,departure:15/11/2025TANYT&leg2=from:iah,to:scl,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}])
-   ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg)
    
    American Airlines
    
    [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:iah,departure:15/11/2025TANYT&leg2=from:iah,to:scl,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}])
-   ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg)
    
    LATAM Airlines Group
    
    [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:iah,departure:15/11/2025TANYT&leg2=from:iah,to:scl,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}])
-   ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg)
    
    Copa
    
    [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:iah,departure:15/11/2025TANYT&leg2=from:iah,to:scl,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}])

-   ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg)
    
    ### 
    
    Be in the know
    
    Get alerts if flight prices drop or rise\*
    
-   ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)
    
    ### 
    
    Book smarter
    
    Save up to 25% on select hotels after you book a flight\*
    
-   ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg)
    
    ### 
    
    Earn twice
    
    Earn your airline miles on top of our rewards
    
    [Sign in](https://www.expedia.co.uk/login)
    

## Cheap Flights from Santiago (SCL) to Houston (IAH)

Prices were available within the past 7 days and start at £325 for one-way flights and £737 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Return

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Thu, 18 Dec - Wed, 31 Dec

SCL

Santiago

IAH

Houston

£737

Return

found 3 days ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:18/12/2025TANYT&leg2=from:IAH,to:SCL,departure:31/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:736.50&airProductToken=AQqVAQowCMGsARIDMjQwGNJYIMEzKLOBgAMwpYSAAzhQQABYAWoFQkFTSUNyCFBFT0IwQlJCCi8IwawBEgI3MBjBMyCSWCjyhYADMKGHgAM4UEABWAFqBUJBU0lDcghQRU9CMEJSQgowCMGsARIDNDI0GJJYIIg4KN2HgAMwlomAAzhQQAFYAWoFQkFTSUNyCFBFT0IwQlI5CpYBCjAIwawBEgMzNjcYiDggklgotJqBAzDom4EDOFBAAFgBagVCQVNJQ3IIUEVPQjBCUjkKMAjBrAESAzM2NRiSWCDBMyjVnoEDMPqfgQM4UEABWAFqBUJBU0lDcghQRU9CMEJSQgowCMGsARIDMTE1GMEzINJYKL-igQMwrKWBAzhQQAFYAWoFQkFTSUNyCFBFT0IwQlJCEgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Thu, 18 Dec - Wed, 31 Dec

SCL

Santiago

IAH

Houston

£748

Return

found 3 days ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:18/12/2025TANYT&leg2=from:IAH,to:SCL,departure:31/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:747.70&airProductToken=AQpgCi4IzIIBEgQ2MzU4GNJYIOBcKMKLgAMwgZCAAzhOQABYAWoCU0xyCE5MWFNMNUdCCi4IzIIBEgQ2Mzk0GOBcIIg4KLqRgAMwx5KAAzhOQAFYAWoCU0xyCE5MWFNMNUdCCo8BCi4IzIIBEgQ2MjM4GIg4IOBcKPaZgQMw8pqBAzhOQABYAWoCU0xyCE5MWFNMNUdCCi4IzIIBEgQ2MTQyGOBcIIwCKL6bgQMwupyBAzhOQAFYAWoCU0xyCE5MWFNMNUdCCi0IzIIBEgM1MDEYjAIg0lgoyZ2BAzC4oYEDOE5AAVgBagJTTHIITkxYU0w1R0ISCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Wed, 17 Dec - Wed, 24 Dec

SCL

Santiago

IAH

Houston

£911

Return

found 4 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:17/12/2025TANYT&leg2=from:IAH,to:SCL,departure:24/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:910.40&airProductToken=AQqWAQowCMGsARIDMTE2GNJYIMEzKI39_wIw-v__AjhQQABYAWoFQkFTSUNyCFBFT0IwQlJCCjAIwawBEgMzNjYYwTMgklgovIOAAzD_hIADOFBAAVgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAzM2OBiSWCCIOCjohYADMKGHgAM4UEABWAFqBUJBU0lDcghQRU9CMEJSOQqhAQo9CMGsARIEMjAwORiIOCDlWijsyIADMIPKgAM4S0AAWAFqBUJBU0lDcghLRU1CMEJSU3oKCNWCARIEMjAwOQovCMGsARICMzcY5VogwTMo8suAAzDOzYADOEtAAVgBagVCQVNJQ3IIS0VNQjBCUlMKLwjBrAESAjk3GMEzINJYKJvPgAMw_tGAAzhLQAFYAWoFQkFTSUNyCEtFTUIwQlJTEgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ)

![Air Canada](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AC.gif)

Wed, 17 Dec - Wed, 24 Dec

SCL

Santiago

IAH

Houston

£943

Return

found 4 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:17/12/2025TANYT&leg2=from:IAH,to:SCL,departure:24/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:942.90&airProductToken=AQqXAQowCMGGARICOTMY0lggmM4BKJv__wIwoISAAzhHQABYAWoFQkFTSUNyCEdMWVQxNkJBCjEIwYYBEgM0MDIYmM4BIJhdKKyFgAMw_oWAAzhHQAFYAWoFQkFTSUNyCEdMWVQxNkJBCjAIwYYBEgM1ODMYmF0giDgohIqAAzCbjIADOEdAAVgBagVCQVNJQ3IIR0xZVDE2QkEKZQoxCMGGARIDNTkwGIg4IJjOASj2yIADMLTKgAM4VEAAWAFqBUJBU0lDcghUTFhTMTZCQQowCMGGARICOTIYmM4BINJYKI7QgAMwk9WAAzhUQAFYAWoFQkFTSUNyCFRMWFMxNkJBEgoIARABGAEqAkFDGAEiBAgBEAEoAigDKAQwAQ)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Mon, 15 Dec - Mon, 22 Dec

SCL

Santiago

IAH

Houston

£947

Return

found 4 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:15/12/2025TANYT&leg2=from:IAH,to:SCL,departure:22/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:946.50&airProductToken=AQqWAQowCMGsARIDMTE2GNJYIMEzKM3m_wIwuun_AjhQQABYAWoFQkFTSUNyCFBFT0IwQlJCCjAIwawBEgMzNjYYwTMgklgo_Oz_AjC_7v8COFBAAVgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAzM2OBiSWCCIOCio7_8CMOHw_wI4UEABWAFqBUJBU0lDcghQRU9CMEJSOQqWAQowCMGsARIDMzY3GIg4IJJYKJS1gAMwyLaAAzhRQABYAWoFQkFTSUNyCFFFT0IwQlJTCjAIwawBEgMzNjUYklggwTMotbmAAzDauoADOFFAAVgBagVCQVNJQ3IIUUVPQjBCUlMKMAjBrAESAzExNRjBMyDSWCifvYADMIzAgAM4UUABWAFqBUJBU0lDcghRRU9CMEJSUxIKCAIQARgCKgJBVhgBIgQIARABKAIoAygEMAE)

![Air Canada](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AC.gif)

Wed, 17 Dec - Wed, 24 Dec

SCL

Santiago

IAH

Houston

£988

Return

found 4 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:17/12/2025TANYT&leg2=from:IAH,to:SCL,departure:24/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:987.60&airProductToken=AQqXAQowCMGGARICOTMY0lggmM4BKJv__wIwoISAAzhLQABYAWoFQkFTSUNyCEtMWlQxNkJBCjEIwYYBEgM0MDIYmM4BIJhdKKyFgAMw_oWAAzhLQAFYAWoFQkFTSUNyCEtMWlQxNkJBCjAIwYYBEgM1ODMYmF0giDgohIqAAzCbjIADOEtAAVgBagVCQVNJQ3IIS0xaVDE2QkESCggBEAEYASoCQUMYASIECAEQASgCKAMoBDAB)

![Air Canada](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AC.gif)

Mon, 15 Dec - Mon, 22 Dec

SCL

Santiago

IAH

Houston

£989

Return

found 4 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:15/12/2025TANYT&leg2=from:IAH,to:SCL,departure:22/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:988.70&airProductToken=AQprCjMIwYYBEgI5MxjSWCCYzgEo2-j_AjDg7f8COEtAAFgBaghTVEFOREFSRHIIS0xaVDE2VEcKNAjBhgESAzU5NRiYzgEgiDgo9vP_AjDg9f8COEtAAVgBaghTVEFOREFSRHIIS0xaVDE2VEcSCggBEAEYASoCQUMYASIECAEQASgCKAMoBDAB)

![Air Canada](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AC.gif)

Mon, 15 Dec - Mon, 22 Dec

SCL

Santiago

IAH

Houston

£1,002

Return

found 4 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:15/12/2025TANYT&leg2=from:IAH,to:SCL,departure:22/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1001.60&airProductToken=AQprCjMIwYYBEgI5MxjSWCCYzgEo2-j_AjDg7f8COEtAAFgBaghTVEFOREFSRHIIS0xaVDE2VEcKNAjBhgESAzU5NRiYzgEgiDgo9vP_AjDg9f8COEtAAVgBaghTVEFOREFSRHIIS0xaVDE2VEcSCggBEAEYASoCQUMYASIECAEQASgCKAMoBDAB)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Wed, 17 Dec - Wed, 24 Dec

SCL

Santiago

IAH

Houston

£1,006

Return

found 4 hours ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:17/12/2025TANYT&leg2=from:IAH,to:SCL,departure:24/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1005.60&airProductToken=AQqhAQowCMGsARIDMTE2GNJYIMEzKI39_wIw-v__AjhXQABYAWoFQkFTSUNyCFdFTUIwQlJTCi4IwawBEgE4GMEzIIwCKJqBgAMwioOAAzhXQAFYAWoFQkFTSUNyCFdFTUIwQlJTCj0IwawBEgQyMDA3GIwCIIg4KMiEgAMw_4WAAzhXQAFYAWoFQkFTSUNyCFdFTUIwQlJTegoI1YIBEgQyMDA3CqEBCj0IwawBEgQyMDA5GIg4IOVaKOzIgAMwg8qAAzhLQABYAWoFQkFTSUNyCEtFTUIwQlJTegoI1YIBEgQyMDA5Ci8IwawBEgIzNxjlWiDBMyjyy4ADMM7NgAM4S0ABWAFqBUJBU0lDcghLRU1CMEJSUwovCMGsARICOTcYwTMg0lgom8-AAzD-0YADOEtAAVgBagVCQVNJQ3IIS0VNQjBCUlMSCggCEAEYAioCQVYYASIECAEQASgCKAMoBDAB)

![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif)

Thu, 18 Dec - Wed, 31 Dec

SCL

Santiago

IAH

Houston

£1,380

Return

found 3 days ago

[](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:IAH,departure:18/12/2025TANYT&leg2=from:IAH,to:SCL,departure:31/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1379.10&airProductToken=AQprCjMIw5oBEgM0NzUY0lgg78QBKJ-CgAMwvIWAAzhVQABYAWoHQ0xBU1NJQ3IIVUFBMlJaME4KNAjDmgESBDE5MzEY78QBIIg4KIOHgAMwhomAAzhVQAFYAWoHQ0xBU1NJQ3IIVUFBMlJaME4Kawo0CMOaARIEMTkzNBiIOCDvxAEoi5uBAzCGnYEDOFNAAFgBagdDTEFTU0lDcghTQUEyUlowTgozCMOaARIDMjc3GO_EASDSWCj0nYEDMP2ggQM4U0ABWAFqB0NMQVNTSUNyCFNBQTJSWjBOEgoIARABGAEqAkNNGAEiBAgBEAEoAigDKAQwAQ)

## Find the cheapest month to fly from Santiago (SCL) to Houston (IAH)

### August is typically the cheapest month to fly

From £471 - £965 per traveller.

## Frequently asked questions

### How much is a flight from Santiago International Airport to George Bush Intercontinental Airport (IAH)?

> If you're planning on travelling from Arturo Merino Benitez Airport (SCL) to George Bush Intercontinental Airport (IAH), round-trip flights start from £737. This figure is based on fares quoted within the last 7 days on Expedia for flights departing within the next year, so don't wait around. Book now and save yourself both money and time. Prices and availability are subject to change. Additional terms apply.

### Do I need to pay a cancellation fee if I cancel my flight from Arturo Merino Benitez Airport (SCL) to Houston Airport?

> This varies between air carriers, as each has its own set of terms and conditions. Visit the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033), where you'll find instructions on how to cancel your flight online.

### How do I find cheap flights from Arturo Merino Benitez Airport (SCL) to IAH that have flexible change policies?

> Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Arturo Merino Benitez Airport (SCL) to Houston Airport flights, you'll see a "no change fees" filter for you to select.

### How far is the flight from SCL to Houston Airport?

> You'll have 7,500 kilometres to cover on the long-haul Santiago to Houston route. Wear layers of comfortable clothes and consider taking a sleep mask and earplugs.

### Which airlines fly direct from Nuevo Pudahuel Airport to Houston Airport?

> A popular choice with many frequent travellers, United Airlines (UA) offers 30 monthly flights from SCL to George Bush Intercontinental Airport (IAH). Pick the one that fits with your travel plans and book your fare today.

### Are SCL to IAH flight tickets cheaper when they're purchased at the last minute?

> Booking last minute from Arturo Merino Benitez Airport (SCL) to IAH can be hit-or-miss. You may be able to score a great bargain, but then again, you could miss out altogether! If you'd rather play it safe and start your travel planning early, Expedia compares flight deals up to 12 months in advance. Just keep in mind that not all airlines release their prices so far in advance. Our top tip? Check back often as updates are made frequently.

## Travel information

| Origin airport | Arturo Merino Benitez |
| --- | --- |
| Destination airport | George Bush Intercontinental |
| Return price | £736 |
| Distance | 7461 km |
| Average flight time | 9 hours 20 mins |

## Book with confidence

### Compare flights from Santiago to Houston easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Santiago to Houston. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to George Bush Intercontinental in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Arturo Merino Benitez to George Bush Intercontinental.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Arturo Merino Benitez (SCL) to George Bush Intercontinental (IAH)

The easiest way to view the best deals on flights from Santiago to Houston today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Arturo Merino Benitez to George Bush Intercontinental start at just £737 and range up to £1,380.  

To find an even better deal, try  

-   being flexible on your dates – midweek flights can be cheaper
-   looking for other airports near Santiago and Houston
-   booking your flight during December, the cheapest month on this route
-   varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Santiago to Houston flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Arturo Merino Benitez to George Bush Intercontinental for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

## Explore a world of travel with Expedia

-   Flights

-   [Flights from Albuquerque (ABQ) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/abq/hou/albuquerque-to-houston)
-   [Flights from Albany (ABY) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/aby/hou/albany-to-houston)
-   [Flights from Aberdeen (ABZ) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/abz/hou/aberdeen-to-houston)
-   [Flights from Albany (ALB) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/alb/hou/albany-to-houston)
-   [Flights from Atlanta (ATL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/atl/hou/atlanta-to-houston)
-   [Flights from Austin (AUS) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/aus/hou/austin-to-houston)
-   [Flights from Belfast (BHD) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/bhd/hou/belfast-to-houston)
-   [Flights from Birmingham (BHM) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/bhm/hou/birmingham-to-houston)
-   [Flights from Birmingham (BHX) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/bhx/hou/birmingham-to-houston)
-   [Flights from Bristol (BRS) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/brs/hou/bristol-to-houston)
-   [Flights from Baltimore (BWI) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/bwi/hou/baltimore-to-houston)
-   [Flights from Guangzhou (CAN) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/can/hou/guangzhou-to-houston)
-   [Flights from Cherbourg (CER) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cer/hou/cherbourg-to-houston)
-   [Flights from Charleston (CHS) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/chs/hou/charleston-to-houston)
-   [Flights from Cedar Rapids (CID) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cid/hou/cedar-rapids-to-houston)
-   [Flights from Charlotte (CLT) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/clt/hou/charlotte-to-houston)
-   [Flights from Columbus (CMH) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cmh/hou/columbus-to-houston)
-   [Flights from Colorado Springs (COS) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cos/hou/colorado-springs-to-houston)
-   [Flights from Cancun (CUN) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cun/hou/cancun-to-houston)
-   [Flights from Cincinnati (CVG) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cvg/hou/cincinnati-to-houston)
-   [Flights from Coventry (CVT) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cvt/hou/coventry-to-houston)
-   [Flights from Cardiff (CWL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/cwl/hou/cardiff-to-houston)
-   [Flights from Washington (DCA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/dca/hou/washington-to-houston)
-   [Flights from Dallas (DFW) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/dfw/hou/dallas-to-houston)
-   [Flights from Dublin (DUB) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/dub/hou/dublin-to-houston)
-   [Flights from Edinburgh (EDI) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/edi/hou/edinburgh-to-houston)
-   [Flights from El Paso (ELP) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/elp/hou/el-paso-to-houston)
-   [Flights from East Midlands (EMA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/ema/hou/east-midlands-to-houston)
-   [Flights from Newark Liberty Intl. Airport (EWR) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/ewr/hou/newark-liberty-intl-airport-to-houston)
-   [Flights from Fresno (FAT) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/fat/hou/fresno-to-houston)
-   [Flights from Fort Lauderdale (FLL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/fll/hou/fort-lauderdale-to-houston)
-   [Flights from Spokane (GEG) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/geg/hou/spokane-to-houston)
-   [Flights from Glasgow (GLA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/gla/hou/glasgow-to-houston)
-   [Flights from Green Bay (GRB) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/grb/hou/green-bay-to-houston)
-   [Flights from Greenville (GSP) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/gsp/hou/greenville-to-houston)
-   [Flights from Harlingen (HRL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/hrl/hou/harlingen-to-houston)
-   [Flights from Indianapolis (IND) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/ind/hou/indianapolis-to-houston)
-   [Flights from Ishurdi (IRD) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/ird/hou/ishurdi-to-houston)
-   [Flights from Jackson Hole (JAC) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/jac/hou/jackson-hole-to-houston)
-   [Flights from New York (JFK) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/jfk/hou/new-york-to-houston)
-   [Flights from Los Angeles (LAX) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/lax/hou/los-angeles-to-houston)
-   [Flights from Leeds (LBA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/lba/hou/leeds-to-houston)
-   [Flights from London (LCY) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/lcy/hou/london-to-houston)
-   [Flights from London (LHR) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/lhr/hou/london-to-houston)
-   [Flights from London (LON) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/lon/hou/london-to-houston)
-   [Flights from Lagos (LOS) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/los/hou/lagos-to-houston)
-   [Flights from Liverpool (LPL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/lpl/hou/liverpool-to-houston)
-   [Flights from Laval (LVA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/lva/hou/laval-to-houston)
-   [Flights from Midland (MAF) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/maf/hou/midland-to-houston)
-   [Flights from Manchester (MAN) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/man/hou/manchester-to-houston)
-   [Flights from Kansas City (MCI) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mci/hou/kansas-city-to-houston)
-   [Flights from Orlando (MCO) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mco/hou/orlando-to-houston)
-   [Flights from Memphis (MEM) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mem/hou/memphis-to-houston)
-   [Flights from Mexico City (MEX) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mex/hou/mexico-city-to-houston)
-   [Flights from Michigan City (MGC) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mgc/hou/michigan-city-to-houston)
-   [Flights from Manchester (MHT) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mht/hou/manchester-to-houston)
-   [Flights from Miami (MIA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mia/hou/miami-to-houston)
-   [Flights from Milwaukee (MKE) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mke/hou/milwaukee-to-houston)
-   [Flights from Durham (MME) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/mme/hou/durham-to-houston)
-   [Flights from New Orleans (MSY) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/msy/hou/new-orleans-to-houston)
-   [Flights from Whitby (NCA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/nca/hou/whitby-to-houston)
-   [Flights from Newcastle (NCL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/ncl/hou/newcastle-to-houston)
-   [Flights from Norwich (NWI) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/nwi/hou/norwich-to-houston)
-   [Flights from New York (NYC) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/nyc/hou/new-york-to-houston)
-   [Flights from Oakland (OAK) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/oak/hou/oakland-to-houston)
-   [Flights from Oklahoma City (OKC) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/okc/hou/oklahoma-city-to-houston)
-   [Flights from Omaha (OMA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/oma/hou/omaha-to-houston)
-   [Flights from Chicago (ORD) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/ord/hou/chicago-to-houston)
-   [Flights from Norfolk (ORF) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/orf/hou/norfolk-to-houston)
-   [Flights from Northampton (ORM) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/orm/hou/northampton-to-houston)
-   [Flights from Oran (ORN) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/orn/hou/oran-to-houston)
-   [Flights from Philadelphia (PHL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/phl/hou/philadelphia-to-houston)
-   [Flights from Phoenix (PHX) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/phx/hou/phoenix-to-houston)
-   [Flights from Pittsburgh (PIT) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/pit/hou/pittsburgh-to-houston)
-   [Flights from Port of Spain (POS) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/pos/hou/port-of-spain-to-houston)
-   [Flights from Pittsfield (PSF) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/psf/hou/pittsfield-to-houston)
-   [Flights from Providence (PVD) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/pvd/hou/providence-to-houston)
-   [Flights from Raleigh (RDU) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/rdu/hou/raleigh-to-houston)
-   [Flights from Roswell (ROW) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/row/hou/roswell-to-houston)
-   [Flights from Fort Myers (RSW) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/rsw/hou/fort-myers-to-houston)
-   [Flights from San Diego (SAN) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/san/hou/san-diego-to-houston)
-   [Flights from Santa Barbara (SBA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/sba/hou/santa-barbara-to-houston)
-   [Flights from San Bernardino (SBD) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/sbd/hou/san-bernardino-to-houston)
-   [Flights from Seattle (SEA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/sea/hou/seattle-to-houston)
-   [Flights from San Francisco (SFO) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/sfo/hou/san-francisco-to-houston)
-   [Flights from San Jose (SJC) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/sjc/hou/san-jose-to-houston)
-   [Flights from San José del Cabo (SJD) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/sjd/hou/san-jose-del-cabo-to-houston)
-   [Flights from Salt Lake City (SLC) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/slc/hou/salt-lake-city-to-houston)
-   [Flights from Sacramento (SMF) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/smf/hou/sacramento-to-houston)
-   [Flights from Southampton (SOU) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/sou/hou/southampton-to-houston)
-   [Flights from St. Louis (STL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/stl/hou/st-louis-to-houston)
-   [Flights from Tampa (TPA) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/tpa/hou/tampa-to-houston)
-   [Flights from Tulsa (TUL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/tul/hou/tulsa-to-houston)
-   [Flights from Texarkana (TXK) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/txk/hou/texarkana-to-houston)
-   [Flights from Washington (WAS) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/was/hou/washington-to-houston)
-   [Flights from Boulder (WBU) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/wbu/hou/boulder-to-houston)
-   [Flights from Wellington (WLG) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/wlg/hou/wellington-to-houston)
-   [Flights from Cornwall (YCC) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/ycc/hou/cornwall-to-houston)
-   [Flights from Langley (YLY) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/yly/hou/langley-to-houston)
-   [Flights from Lethbridge (YQL) to Houston (HOU)](https://www.expedia.co.uk/lp/flights/yql/hou/lethbridge-to-houston)

\*Available to Expedia members.