Title: £549 Cheap Flights from Panama City to Santa Cruz de Tenerife (PTY to TCI) - Expedia.co.uk ![Teresitas Beach which includes swimming, general coastal views and a sandy beach](https://images.trvl-media.com/place/6067523/fbd88094-fef6-4e47-99fa-ade735541656.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6067523/fbd88094-fef6-4e47-99fa-ade735541656.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £549 Cheap Flights from Panama City (PTY) to Santa Cruz de Tenerife (TCI) [View £549 flight on Thu, 25 Dec 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:548.40&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlPN0wKLgjVsAESBDkwNTcYjBggs2ko3eGAAzCM44ADOFRAAVgBagRMSVRFcgZUTFlPN0wSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Tocumen Intl. Airport (PTY) to Santa Cruz de Tenerife - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:tci,departure:06/11/2025TANYT&leg2=from:tci,to:pty,departure:13/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) - ![Air Europa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UX.svg) Air Europa [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:tci,departure:06/11/2025TANYT&leg2=from:tci,to:pty,departure:13/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UX"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:tci,departure:06/11/2025TANYT&leg2=from:tci,to:pty,departure:13/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:tci,departure:06/11/2025TANYT&leg2=from:tci,to:pty,departure:13/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:tci,departure:06/11/2025TANYT&leg2=from:tci,to:pty,departure:13/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:tci,departure:06/11/2025TANYT&leg2=from:tci,to:pty,departure:13/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![Aeromexico](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AM.svg) Aeromexico [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:tci,departure:06/11/2025TANYT&leg2=from:tci,to:pty,departure:13/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AM"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Panama City (PTY) to Santa Cruz de Tenerife (TCI) Prices were available within the past 7 days and start at £549 for one-way flights and £990 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £990 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:989.10&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlSN0wKLgjVsAESBDkwNTcYjBggs2ko3eGAAzCM44ADOFRAAVgBagRMSVRFcgZUTFlSN0wKmwEKMgjVsAESBDIxMTgYs2kg6wMo1NKBAzDy0oEDOFFAAFgBaghTVEFOREFSRHIGUUhZUkFFCjII1bABEgQ5MDE4GOsDIIwYKK7YgQMw09mBAzhRQAFYAWoIU1RBTkRBUkRyBlFIWVJBRQoxCNWwARICNTUYjBgg78QBKNLbgQMwzeCBAzhRQAFYAWoIU1RBTkRBUkRyBlFIWVJBRRIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £992 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:991.80&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlSN0wKLgjVsAESBDkwNDgYjBggs2ko6N-AAzCX4YADOFRAAVgBagRMSVRFcgZUTFlSN0wKmwEKMgjVsAESBDIxMTUYs2kg6wMo3s2BAzD8zYEDOFFAAFgBaghTVEFOREFSRHIGUUhZUkFFCjII1bABEgQ5MDE4GOsDIIwYKK7YgQMw09mBAzhRQAFYAWoIU1RBTkRBUkRyBlFIWVJBRQoxCNWwARICNTUYjBgg78QBKNLbgQMwzeCBAzhRQAFYAWoIU1RBTkRBUkRyBlFIWVJBRRIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,013 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1012.60&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlSN0wKLgjVsAESBDkwNTcYjBggs2ko3eGAAzCM44ADOFRAAVgBagRMSVRFcgZUTFlSN0wKXwouCNWwARIEOTA0NRizaSCMGCiJzYEDMK7OgQM4VUAAWAFqBExJVEVyBlVIWVI3TAotCNWwARICNTUYjBgg78QBKLLQgQMwrdWBAzhVQAFYAWoETElURXIGVUhZUjdMEgoIARABGAEqAlVYGAEiBAgBEAEoAigDKAQwAQ) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,021 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1020.10&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlSN0wKLgjVsAESBDkwNDgYjBggs2ko6N-AAzCX4YADOFRAAVgBagRMSVRFcgZUTFlSN0wKmwEKMgjVsAESBDIxMTUYs2kg6wMo3s2BAzD8zYEDOFRAAFgBaghTVEFOREFSRHIGVEhZUkFFCjII1bABEgQ5MTYxGOsDIIwYKLjOgQMw3c-BAzhUQAFYAWoIU1RBTkRBUkRyBlRIWVJBRQoxCNWwARICNTUYjBgg78QBKLLQgQMwrdWBAzhUQAFYAWoIU1RBTkRBUkRyBlRIWVJBRRIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,045 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1044.70&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlSN0wKLgjVsAESBDkwNDgYjBggs2ko6N-AAzCX4YADOFRAAVgBagRMSVRFcgZUTFlSN0wKXwouCNWwARIEOTA0NxizaSCMGCizzoEDMNjPgQM4UkAAWAFqBExJVEVyBlJIWVI3TAotCNWwARICNTUYjBgg78QBKLLQgQMwrdWBAzhSQAFYAWoETElURXIGUkhZUjdMEgoIARABGAEqAlVYGAEiBAgBEAEoAigDKAQwAQ) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,256 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1255.50&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlSN0wKLgjVsAESBDkwNTcYjBggs2ko3eGAAzCM44ADOFRAAVgBagRMSVRFcgZUTFlSN0wKmgEKMQjQmgESAzYxNhizaSDrAyjezYEDMPzNgQM4WUAAWAFqCFNUQU5EQVJEcgZLSFlSQUUKMgjVsAESBDkxNjEY6wMgjBgouM6BAzDdz4EDOEtAAVgBaghTVEFOREFSRHIGS0hZUkFFCjEI1bABEgI1NRiMGCDvxAEostCBAzCt1YEDOEtAAVgBaghTVEFOREFSRHIGS0hZUkFFEgoIARABGAEqAlVYGAEiBAgBEAEoAigDKAQwAQ) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,374 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1373.60&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgottqAAzD13oADOFRAAFgBagRMSVRFcgZUTFlPN0wKLgjVsAESBDkwNTcYjBggs2ko3eGAAzCM44ADOFRAAVgBagRMSVRFcgZUTFlPN0wSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,548 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1547.60&airProductToken=AQqaAQoxCMGsARICNTcY78QBIMEzKNrYgAMwvtmAAzhQQABYAWoGT1BUSU1BcghCREwwTk5NNwoxCMmEARIDMTU0GMEzIIwYKPfagAMwtt-AAzhCQAFYAWoGT1BUSU1BcghCREwwTk5NNwoyCMmEARIEMTU4ORiMGCCzaSjG4oADMPXjgAM4QkABWAFqBk9QVElNQXIIQkRMME5OTTcKZgoxCMmEARIEMTU5MBizaSCMGCj6zIEDMKTOgQM4QkAAWAFqBUJBU0lDcghCTkgwTk5CNwoxCMmEARIDMjU3GIwYIO_EASjgzoEDMPnTgQM4QkABWAFqBUJBU0lDcghCTkgwTk5CNxIKCAEQARgBKgJJQhgBIgQIARABKAIoAygEMAE) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,613 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1612.90&airProductToken=AQqaAQoxCMGsARICNTcY78QBIMEzKNrYgAMwvtmAAzhQQABYAWoGT1BUSU1BcghCREwwTk5NNwoxCMmEARIDMTU0GMEzIIwYKPfagAMwtt-AAzhCQAFYAWoGT1BUSU1BcghCREwwTk5NNwoyCMmEARIEMTU4ORiMGCCzaSjG4oADMPXjgAM4QkABWAFqBk9QVElNQXIIQkRMME5OTTcKnAEKMgjJhAESBDE1NzgYs2kgjBgorNKBAzDR04EDOEJAAFgBagZPUFRJTUFyCEJESDBOTk03CjEIyYQBEgMyNDMYjBggsnIordqBAzDL34EDOEJAAVgBagZPUFRJTUFyCEJESDBOTk03CjMIyYQBEgQ3NzY5GLJyIO_EASio4IEDMPrggQM4UUABWAFqBk9QVElNQXIIQkRIME5OTTcSCggBEAEYASoCSUIYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,619 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1618.20&airProductToken=AQqaAQoxCMGsARICNTcY78QBIMEzKNrYgAMwvtmAAzhQQABYAWoGT1BUSU1BcghCREwwTk9NNwoxCMmEARIDMTU0GMEzIIwYKPfagAMwtt-AAzhCQAFYAWoGT1BUSU1BcghCREwwTk9NNwoyCMmEARIEMTU4ORiMGCCzaSjG4oADMPXjgAM4QkABWAFqBk9QVElNQXIIQkRMME5PTTcSCggBEAEYASoCSUIYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,621 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1620.90&airProductToken=AQqaAQoxCMGsARICNTcY78QBIMEzKNrYgAMwvtmAAzhQQABYAWoGT1BUSU1BcghCREwwTk9NNwoxCMmEARIDMTU0GMEzIIwYKPfagAMwtt-AAzhCQAFYAWoGT1BUSU1BcghCREwwTk9NNwoyCMmEARIEMTU4ORiMGCCzaSjG4oADMPXjgAM4QkABWAFqBk9QVElNQXIIQkRMME5PTTcSCggBEAEYASoCSUIYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,669 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1668.20&airProductToken=AQqaAQoxCMGsARICNTcY78QBIMEzKNrYgAMwvtmAAzhQQABYAWoGT1BUSU1BcghCREwwTk9NNwoxCMmEARIDMTU0GMEzIIwYKPfagAMwtt-AAzhCQAFYAWoGT1BUSU1BcghCREwwTk9NNwoyCMmEARIEMTU4ORiMGCCzaSjG4oADMPXjgAM4QkABWAFqBk9QVElNQXIIQkRMME5PTTcSCggBEAEYASoCSUIYASIECAEQASgCKAMoBDAB) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £1,731 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1730.20&airProductToken=AQqbAQoyCMuYARIDNzU4GO_EASCAkwEokdmAAzCC3oADOFVAAFgBagVMSUdIVHIIVVJMMEFCTEEKMgjLmAESBDE1MDUYgJMBIIwYKI7fgAMwqeCAAzhZQAFYAWoFTElHSFRyCFVSTDBBQkxBCjEIy5gBEgQzMzc4GIwYILNpKN3hgAMwjOOAAzhZQAFYAWoFTElHSFRyCFVSTDBBQkxBCpsBCjEIy5gBEgQzMzczGLNpIIwYKLPOgQMw2M-BAzhZQABYAWoFTElHSFRyCFVSTDBBQkxBCjIIy5gBEgQxNTA4GIwYIICTASjy0oEDMI3UgQM4WUABWAFqBUxJR0hUcghVUkwwQUJMQQoyCMuYARIDNzU3GICTASDvxAEo7NmBAzCK34EDOFVAAVgBagVMSUdIVHIIVVJMMEFCTEESCggBEAEYASoCS0wYASIECAEQASgCKAMoBDAB) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 25 Dec - Mon, 5 Jan PTY Panama City TFN Tenerife £2,065 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:TFN,departure:25/12/2025TANYT&leg2=from:TFN,to:PTY,departure:05/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:2064.30&airProductToken=AQqcAQozCMmEARIENDM2ORjvxAEgjAIoqdeAAzDr2IADOFlAAFgBagZPUFRJTUFyCFlETjBOTk03CjEIyYQBEgMzMzgYjAIgjBgo8tqAAzD13oADOFlAAVgBagZPUFRJTUFyCFlETjBOTk03CjIIyYQBEgQxNTg5GIwYILNpKMbigAMw9eOAAzhZQAFYAWoGT1BUSU1BcghZRE4wTk5NNwpmCjEIyYQBEgQxNTkwGLNpIIwYKPrMgQMwpM6BAzhCQABYAWoFQkFTSUNyCEJOSDBOTkI3CjEIyYQBEgMyNTcYjBgg78QBKODOgQMw-dOBAzhCQAFYAWoFQkFTSUNyCEJOSDBOTkI3EgoIARABGAEqAklCGAEiBAgBEAEoAigDKAQwDQ) Flight from Panama City to Santa Cruz de Tenerife route information | Origin airport | Tocumen Intl. | | --- | --- | | Destination airport | Tenerife North | | Return price | £989 | | Distance | 6859 km | ## Compare flights from Panama City to Santa Cruz de Tenerife easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Santa Cruz de Tenerife. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to TCI-All Airports in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to TCI-All Airports.   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Tocumen Intl. (PTY) to TCI-All Airports (TCI) The easiest way to view the best deals on flights from Panama City to Santa Cruz de Tenerife today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to TCI-All Airports start at just £990 and range up to £2,065.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Panama City and Santa Cruz de Tenerife - booking your flight during December, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Panama City to Santa Cruz de Tenerife flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to TCI-All Airports for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Flights ### Flights - [Flights from Aberdeen (ABZ) to Tenerife (TFS)](https://www.expedia.co.uk/lp/flights/abz/tfs/aberdeen-to-tenerife) - [Flights from Arrecife (ACE) to Tenerife (TFS)](https://www.expedia.co.uk/lp/flights/ace/tfs/arrecife-to-tenerife) - [Flights from Málaga (AGP) to Tenerife (TFS)](https://www.expedia.co.uk/lp/flights/agp/tfs/malaga-to-tenerife) - [Flights from Alicante (ALC) to Tenerife (TFS)](https://www.expedia.co.uk/lp/flights/alc/tfs/alicante-to-tenerife) - [Flights from Amsterdam (AMS) to Tenerife (TFS)](https://www.expedia.co.uk/lp/flights/ams/tfs/amsterdam-to-tenerife) - [Flights from Stockholm (ARN) to Tenerife (TFS)](https://www.expedia.co.uk/lp/flights/arn/tfs/stockholm-to-tenerife) - [Flights from Athens (ATH) to Tenerife (TFS)](https://www.expedia.co.uk/lp/flights/ath/tfs/athens-to-tenerife) - 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