Title: £363 Cheap Flights from Panama City to Santiago (PTY to STI) - Expedia.co.uk ![Santiago featuring heritage architecture](https://images.trvl-media.com/place/3283/431eeeaf-b925-402d-9f33-099a1329abf2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ministry of Tourism of the Dominican Republic ![](https://images.trvl-media.com/place/3283/431eeeaf-b925-402d-9f33-099a1329abf2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £363 Cheap Flights from Panama City (PTY) to Santiago (STI) [View £363 flight on Thu, 15 Jan 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:PTY,to:STI,departure:15/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:362.50&airProductToken=AQozCjEIw5oBEgM0ODAY78QBIPJEKPrBggMwkMOCAzhRQABYAWoFQkFTSUNyCFFMQUFPWTJTEgoIARABGAEqAkNNGAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Tocumen Intl. Airport (PTY) to Cibao Intl. Airport (STI) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:STI,departure:25/12/2025TANYT&leg2=from:STI,to:PTY,departure:01/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:STI,departure:25/12/2025TANYT&leg2=from:STI,to:PTY,departure:01/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:STI,departure:25/12/2025TANYT&leg2=from:STI,to:PTY,departure:01/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Panama City (PTY) to Santiago (STI) Prices were available within the past 7 days and start at £363 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ## Find the cheapest month to fly from Panama City (PTY) to Santiago de los Caballeros (STI) ### February is typically the cheapest month to fly From £288 - £1,341 per traveller. __Flight from Panama City to Santiago route information__ | Origin airport | Tocumen Intl. | | ------------------- | ------------- | | Destination airport | Cibao Intl. | | Distance | 1479 km | ## Compare flights from Panama City to Santiago easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Santiago. Operating between them flights per day, 6 airlines cover the route. And fly direct, getting you to Cibao Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to Cibao Intl.. To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. Grab a great deal on your flight from Tocumen Intl. (PTY) to Cibao Intl. (STI) The easiest way to view the best deals on flights from Panama City to Santiago today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to Cibao Intl. start at just and range up to . To find an even better deal, try - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Panama City and Santiago - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper Why you should book your Panama City to Santiago flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to Cibao Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you. Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight. ## Frequently asked questions ### How much is a flight from Tocumen Intl. Airport (PTY) to STI? ### Do I need to pay a cancellation fee if I cancel my flight from Panama Airport to Cibao Intl. Airport (STI)? ### How do I find cheap flights from Tocumen Intl. Airport (PTY) to Santiago Airport that have flexible change policies? ### How many hours is the flight from PTY to Cibao Intl. Airport (STI)? ### How far is the flight from Tocumen Intl. Airport (PTY) to Cibao Intl. Airport (STI)? ### Which airlines fly direct from PTY to Cibao Intl. Airport (STI)? ### Are Tocumen Intl. Airport (PTY) to STI flight tickets cheaper when they're purchased at the last minute? ## Explore a world of travel with Expedia - Accommodation - Packages - Cars ### Accommodation - [Hotels near Catedral de Santiago ](https://www.expedia.co.uk/Catedral-De-Santiago-Hotels.0-l6099846-0.Travel-Guide-Filter-Hotels) - [Cerro Alto Hotels ](https://www.expedia.co.uk/Cerro-Alto-Santiago-De-Los-Caballeros-Hotels.0-n553248635976384648-0.Travel-Guide-Filter-Hotels) - [Cerros de Gurabo Hotels ](https://www.expedia.co.uk/Cerros-De-Gurabo-Santiago-De-Los-Caballeros-Hotels.0-n553248635975850536-0.Travel-Guide-Filter-Hotels) - [Santiago Province Hotels ](https://www.expedia.co.uk/Destinations-In-Santiago-Province.d6247205.Hotel-Destinations) - [Gay-Friendly Hotels in Gregorio Luperón ](https://www.expedia.co.uk/Gregorio-Luperon-Santiago-De-Los-Caballeros-Hotels-Gay-Friendly-Hotel.0-n553248635976398799-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Jánico Hotels ](https://www.expedia.co.uk/Janico-Hotels.d553248635973480032.Travel-Guide-Hotels) - [La Joya Hotels ](https://www.expedia.co.uk/La-Joya-Hotels.d553248635976385446.Travel-Guide-Hotels) - [La Zurza III Hotels ](https://www.expedia.co.uk/La-Zurza-III-Santiago-De-Los-Caballeros-Hotels.0-n553248635976399685-0.Travel-Guide-Filter-Hotels) - [Licey al Medio Hotels ](https://www.expedia.co.uk/Licey-Al-Medio-Hotels.d553248635973480069.Travel-Guide-Hotels) - [Los Pepines Hotels ](https://www.expedia.co.uk/Los-Pepines-Santiago-De-Los-Caballeros-Hotels.0-n553248635976384556-0.Travel-Guide-Filter-Hotels) - [Puñal Hotels ](https://www.expedia.co.uk/Punal-Hotels.d553248635973480067.Travel-Guide-Hotels) - [Rincón Largo Hotels ](https://www.expedia.co.uk/Rincon-Largo-Hotels.d553248635975855897.Travel-Guide-Hotels) - [Sabana Iglesia Hotels ](https://www.expedia.co.uk/Sabana-Iglesia-Hotels.d553248635973469071.Travel-Guide-Hotels) - [Simon Diaz Hotels ](https://www.expedia.co.uk/Simon-Diaz-Santiago-De-Los-Caballeros-Hotels.0-n553248635976399192-0.Travel-Guide-Filter-Hotels) - [Tamboril Hotels ](https://www.expedia.co.uk/Tamboril-Hotels.d3000399154.Travel-Guide-Hotels) - [Villa González Hotels ](https://www.expedia.co.uk/Villa-Gonzalez-Hotels.d553248635973467874.Travel-Guide-Hotels) - [Yaque Arriba Hotels ](https://www.expedia.co.uk/Yaque-Arriba-Hotels.d3000001634.Travel-Guide-Hotels) ### Packages - [Visit Licey al Medio ](https://www.expedia.co.uk/Licey-Al-Medio.dx553248635973480069) - [Visit Sabana Iglesia ](https://www.expedia.co.uk/Sabana-Iglesia.dx553248635973469071) - [Visit La Zurza ](https://www.expedia.co.uk/Santiago-De-Los-Caballeros-La-Zurza.dx553248635976384848) ### Cars - [Car hire near Santiago Province ](https://www.expedia.co.uk/Destinations-In-Santiago-Province.d6247205.Car-Hire-Destinations) \*Available to Expedia members.