Title: £401 Cheap Flights from Panama City to Rome (PTY to FCO) - Expedia.co.uk ![Rome sunset city skyline at Rome Colosseum (Roma Coliseum), Rome, Italy](https://images.trvl-media.com/place/179899/eb7e249d-ccd0-4342-bf0d-7a6024d66dc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £401 Cheap Flights from Panama City (PTY) to Rome (FCO) [View £401 flight on Mon, 24 Nov 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:PTY,to:FCO,departure:24/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:400.30&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgo1v39AjCVgv4COEFAAFgBagRMSVRFcgZBWVlPMkwKLgjVsAESBDEwNDcYjBggxXAoiIP-AjCZhP4COEFAAVgBagRMSVRFcgZBWVlPMkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Tocumen Intl. Airport (PTY) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:fco,departure:20/10/2025TANYT&leg2=from:fco,to:pty,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) - ![Turkish Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TK.svg) Turkish Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:fco,departure:20/10/2025TANYT&leg2=from:fco,to:pty,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TK"}}]) - ![Air Europa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UX.svg) Air Europa [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:fco,departure:20/10/2025TANYT&leg2=from:fco,to:pty,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UX"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:fco,departure:20/10/2025TANYT&leg2=from:fco,to:pty,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:fco,departure:20/10/2025TANYT&leg2=from:fco,to:pty,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:fco,departure:20/10/2025TANYT&leg2=from:fco,to:pty,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:fco,departure:20/10/2025TANYT&leg2=from:fco,to:pty,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Panama City (PTY) to Rome (FCO) Prices were available within the past 7 days and start at £401 for one-way flights and £397 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Condor](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DE.gif) Thu, 16 Oct - Wed, 22 Oct PTY Panama City FCO Rome £397 Return found 2 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:16/10/2025TANYT&leg2=from:FCO,to:PTY,departure:22/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:396.39&airProductToken=AQpnCjIIxIoBEgQyMjM3GO_EASClBCiFwvoCMKPH-gI4WUAAWAFqC0VDT05PTVlaRVJPcgJMTQoxCMSKARIENDQxORilBCDFcCjxy_oCMN_M-gI4WUAAWAFqC0VDT05PTVlaRVJPcgJMTQpnCjEIxIoBEgQ0NDE4GMVwIKUEKPyA-wIw6oH7AjhZQABYAWoLRUNPTk9NWVpFUk9yAkxNCjIIxIoBEgQyMjM2GKUEIO_EASimh_sCMOyM-wI4WUAAWAFqC0VDT05PTVlaRVJPcgJMTRIKCAsQARgIKgJERRgBIgQIARABKAIwAw) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £557 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:556.60&airProductToken=AQqXAQowCMGsARICNTcY78QBIMEzKN_HhAMwvsiEAzhTQABYAWoFTElHSFRyCEdSTDBBSExBCjAIwYwBEgM0MjMYwTMg4jAou8mEAzCnzoQDOEdAAVgBagVMSUdIVHIIR1JMMEFITEEKMQjBjAESBDEwMDQY4jAgxXAovNGEAzC50oQDOExAAVgBagVMSUdIVHIIR1JMMEFITEEKaAoyCMuYARIEMTYwOBjFcCCAkwEojaCFAzCooYUDOExAAFgBagVMSUdIVHIIR1JMMEFITEEKMgjLmAESAzc1NxiAkwEg78QBKIynhQMwqqyFAzhHQAFYAWoFTElHSFRyCEdSTDBBSExBEgoIARABGAEqAkFGGAEiBAgBEAEoAigDKAQwAQ) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £567 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:566.60&airProductToken=AQqXAQowCMGsARICNTcY78QBIMEzKN_HhAMwvsiEAzhTQABYAWoFTElHSFRyCEdSTDBBSExBCjAIwYwBEgM0MjMYwTMg4jAou8mEAzCnzoQDOEdAAVgBagVMSUdIVHIIR1JMMEFITEEKMQjBjAESBDEwMDQY4jAgxXAovNGEAzC50oQDOExAAVgBagVMSUdIVHIIR1JMMEFITEEKZgoxCMGMARIEMTQwNRjFcCDiMCihoIUDMKOhhQM4TEAAWAFqBUxJR0hUcghHUkwwQUhMQQoxCMGMARIDNDc4GOIwIO_EASjyqIUDMIauhQM4R0ABWAFqBUxJR0hUcghHUkwwQUhMQRIKCAEQARgBKgJBRhgBIgQIARABKAIoAygEMAE) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £625 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:624.10&airProductToken=AQqXAQowCMGsARICNTcY78QBIMEzKN_HhAMwvsiEAzhTQABYAWoFTElHSFRyCEdSTDBBSExBCjAIwYwBEgM0MjMYwTMg4jAou8mEAzCnzoQDOEdAAVgBagVMSUdIVHIIR1JMMEFITEEKMQjBjAESBDEwMDQY4jAgxXAovNGEAzC50oQDOExAAVgBagVMSUdIVHIIR1JMMEFITEEKnQEKMgjBtAESBDE2ODEYxXAg5YoBKN2ghQMwlKGFAzhPQABYAWoFTElHSFRyCEdSTDBBSExBCjMIy5gBEgQxNjUwGOWKASCAkwEo9KSFAzD7pYUDOExAAVgBagVMSUdIVHIIR1JMMEFITEEKMgjLmAESAzc1NxiAkwEg78QBKIynhQMwqqyFAzhHQAFYAWoFTElHSFRyCEdSTDBBSExBEgoIARABGAEqAkFGGAEiBAgBEAEoAigDKAQwAQ) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £626 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:625.70&airProductToken=AQqXAQowCMGsARICNTcY78QBIMEzKN_HhAMwvsiEAzhTQABYAWoFTElHSFRyCEdSTDBBSExBCjAIwYwBEgM0MjMYwTMg4jAou8mEAzCnzoQDOEdAAVgBagVMSUdIVHIIR1JMMEFITEEKMQjBjAESBDEwMDQY4jAgxXAovNGEAzC50oQDOExAAVgBagVMSUdIVHIIR1JMMEFITEEKmwEKMQjBtAESBDE0NzMYxXAg1SAo3aCFAzCeoYUDOE9AAFgBagVMSUdIVHIIR1JMMEFITEEKMgjLmAESBDE2MjgY1SAggJMBKOqkhQMw7KWFAzhMQAFYAWoFTElHSFRyCEdSTDBBSExBCjIIy5gBEgM3NTcYgJMBIO_EASiMp4UDMKqshQM4R0ABWAFqBUxJR0hUcghHUkwwQUhMQRIKCAEQARgBKgJBRhgBIgQIARABKAIoAygEMAE) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £637 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:636.10&airProductToken=AQqXAQowCMGsARICNTcY78QBIMEzKN_HhAMwvsiEAzhTQABYAWoFTElHSFRyCEdSTDBBSExBCjAIwYwBEgM0MjMYwTMg4jAou8mEAzCnzoQDOEdAAVgBagVMSUdIVHIIR1JMMEFITEEKMQjBjAESBDEwMDQY4jAgxXAovNGEAzC50oQDOExAAVgBagVMSUdIVHIIR1JMMEFITEEKlwEKMQjBjAESBDEyMDUYxXAg4jAol5uFAzCenIUDOExAAFgBagVMSUdIVHIIUlJMMEtCTEEKMAjBjAESAzQyMhjiMCDBMyilnYUDMLmihQM4UkABWAFqBUxJR0hUcghSUkwwS0JMQQowCMGsARICNDAYwTMg78QBKJWkhQMwiKWFAzhTQAFYAWoFTElHSFRyCFJSTDBLQkxBEgoIARABGAEqAkFGGAEiBAgBEAEoAigDKAQwAQ) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £654 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:653.10&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgotsmEAzD1zYQDOE5AAFgBagRMSVRFcgZOTFlSN0wKLgjVsAESBDEwNDMYjBggxXAordaEAzC-14QDOE5AAVgBagRMSVRFcgZOTFlSN0wKXwouCNWwARIEMTA0MBjFcCCMGCi6m4UDMNWchQM4QUAAWAFqBExJVEVyBkFMWVI3TAotCNWwARICNTUYjBgg78QBKNKdhQMwzaKFAzhBQAFYAWoETElURXIGQUxZUjdMEgoIARABGAEqAlVYGAEiBAgBEAEoAigDKAQwAQ) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £661 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:661.00&airProductToken=AQpfCi0I1bABEgI1NhjvxAEgjBgotsmEAzD1zYQDOE5AAFgBagRMSVRFcgZOTFlSN0wKLgjVsAESBDEwNDMYjBggxXAordaEAzC-14QDOE5AAVgBagRMSVRFcgZOTFlSN0wKXwouCNWwARIEMTA0OBjFcCCMGCiVn4UDMLCghQM4QUAAWAFqBExJVEVyBkFMWVI3TAotCNWwARICNTUYjBgg78QBKPKohQMw7a2FAzhBQAFYAWoETElURXIGQUxZUjdMEgoIARABGAEqAlVYGAEiBAgBEAEoAigDKAQwAQ) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Fri, 16 Jan - Sat, 24 Jan PTY Panama City FCO Rome £683 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:16/01/2026TANYT&leg2=from:FCO,to:PTY,departure:24/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:683.00&airProductToken=AQqgAQo0CMOaARIDODA4GO_EASCpUSiJ0oIDML_UggM4RUAAWAFqCFNUQU5EQVJEcghMTFdBRTZFUwozCNOWARIDOTE2GKlRIOI7KKvbggMw8t6CAzhMQAFYAWoIU1RBTkRBUkRyCExMV0FFNkVTCjMI05YBEgM2ODEY4jsgxXAouN-CAzDT4IIDOExAAVgBaghTVEFOREFSRHIITExXQUU2RVMKoAEKMwjTlgESAzY4MhjFcCDiOyjApIMDMNulgwM4TEAAWAFqCFNUQU5EQVJEcghMTFdBRTZFUwozCNOWARIDOTI1GOI7IIgYKKamgwMw1qqDAzhMQAFYAWoIU1RBTkRBUkRyCExMV0FFNkVTCjQIw5oBEgM0MDMYiBgg78QBKNStgwMwgbCDAzhFQAFYAWoIU1RBTkRBUkRyCExMV0FFNkVTEgoIARABGAEqAlNLGAEiBAgBEAEoAigDKAQwAQ) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Sat, 7 Feb - Sun, 15 Feb PTY Panama City FCO Rome £718 Return found 4 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:FCO,departure:07/02/2026TANYT&leg2=from:FCO,to:PTY,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:717.90&airProductToken=AQplCjEIyYQBEgMyNTgY78QBIIwYKPjHhAMw1cyEAzhRQABYAWoFQkFTSUNyCFFOTDBOTkI3CjAIyYQBEgM2NTUYjBggxXAo5c-EAzD20IQDOFFAAVgBagVCQVNJQ3IIUU5MME5OQjcKmQEKMQjJhAESAzY1NhjFcCCMGCiIoIUDMKOhhQM4TkAAWAFqBk9QVElNQXIITkRMME5OTTcKMQjJhAESAzE1NRiMGCDBMyjfoYUDMNWmhQM4TkABWAFqBk9QVElNQXIITkRMME5OTTcKMQjBrAESAjU4GMEzIO_EASj1p4UDMN6ohQM4V0ABWAFqBk9QVElNQXIITkRMME5OTTcSCggBEAEYASoCSUIYASIECAEQASgCKAMoBDAB) ## Find the cheapest month to fly from Panama City (PTY) to Rome (FCO) ### September is typically the cheapest month to fly From £402 - £897 per traveller. ## Alternative airports near Rome Prices were available within the past 7 days. Prices and availability are subject to change. [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:FCO,departure:20/10/2025TANYT&leg2=from:FCO,to:PTY,departure:26/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) FCO Fiumicino - Leonardo da Vinci Intl. Cheapest 26 min [Flights from £928](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:FCO,departure:20/10/2025TANYT&leg2=from:FCO,to:PTY,departure:26/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) ## Frequently asked questions ### How much is a flight from Panama Airport to FCO? > If you're travelling between Tocumen Intl. Airport (PTY) and Rome Airport, round-trip flights start from £397. This figure is based on fares available within the last 7 days on Expedia for flights departing within the next year, so don't let a good deal slip through your fingers. Book today and save yourself money and time. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Tocumen Intl. Airport (PTY) to FCO? > This can vary from airline to airline, as each has its own set of terms and conditions. Head to the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033), where there are easy-to-follow instructions on how to cancel online. ### How do I find cheap flights from Tocumen Intl. Airport (PTY) to Rome Airport that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for PTY to FCO flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from Panama Airport to Fiumicino Airport? > The distance is around 9,500 kilometres. Travel pillow? Check. Toothbrush? Double check. We recommend you pack all the essentials for this long-haul Tocumen to Fiumicino flight. ### Which airlines fly direct from Tocumen Intl. Airport (PTY) to Rome Airport? > At present, no airlines offer direct flights from Tocumen Intl. Airport (PTY) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO). You'll need to book a flight with at least one stop. To get the best connections and price, lock in your airfare ahead of time. ### Are Tocumen Intl. Airport (PTY) to Fiumicino Airport flight tickets cheaper when they're purchased at the last minute? > Last-minute planners can occasionally nab a bargain, with some super cheap airfares from PTY to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) popping up a few weeks before the date of departure. If you'd rather plan ahead, Expedia compares and updates all the best flight deals frequently — as early as a year in advance in some cases. It does depend on the carrier though, as not all airlines advertise prices that far in advance. ## Travel information | Origin airport | Tocumen Intl. | | --- | --- | | Destination airport | Fiumicino - Leonardo da Vinci Intl. | | Airlines serving | Air Europa, Air France, Iberia, KLM, Turkish Airlines | | Return price | £396 | | Distance | 9416 km | ## Book with confidence ### Compare flights from Panama City to Rome easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Rome. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Fiumicino - Leonardo da Vinci Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to Fiumicino - Leonardo da Vinci Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Tocumen Intl. (PTY) to Fiumicino - Leonardo da Vinci Intl. (FCO) The easiest way to view the best deals on flights from Panama City to Rome today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to Fiumicino - Leonardo da Vinci Intl. start at just £397 and range up to £718.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Panama City and Rome - booking your flight during October, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Panama City to Rome flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to Fiumicino - Leonardo da Vinci Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Flights - [Flights from Aberdeen (ABZ) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/abz/rom/aberdeen-to-rome) - [Flights from Agen (AGF) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/agf/rom/agen-to-rome) - [Flights from Ancona (AOI) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/aoi/rom/ancona-to-rome) - [Flights from Athens (ATH) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/ath/rom/athens-to-rome) - [Flights from Altamira (ATM) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/atm/rom/altamira-to-rome) - [Flights from Abu Dhabi (AUH) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/auh/rom/abu-dhabi-to-rome) - [Flights from Avignon (AVN) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/avn/rom/avignon-to-rome) - [Flights from Brindisi (BDS) to Rome (ROM)](https://www.expedia.co.uk/lp/flights/bds/rom/brindisi-to-rome) - 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