£437 Cheap Flights from New Orleans (MSY) to Tupelo (TUP)

View £437 flight on Tue, 16 Jun 2026Opens in a new window

Popular airlines from Louis Armstrong New Orleans Intl. Airport (MSY) to Tupelo, MS (TUP-Tupelo Regional)

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Cheap Flights from New Orleans (MSY) to Tupelo (TUP)

Prices were available within the past 7 days and start at £437 for one-way flights and £919 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines
Tue, 16 Jun - Tue, 23 Jun
MSY
New Orleans
TUP
Tupelo
£919 Return, found 6 days ago
£919
Return
found 6 days ago
Select Alaska Airlines flight, departing Tue, 16 Jun from New Orleans to Tupelo, returning Tue, 23 Jun, priced at £919 found 6 days ago
Alaska Airlines
Tue, 16 Jun - Tue, 23 Jun
MSY
New Orleans
TUP
Tupelo
£926 Return, found 6 days ago
£926
Return
found 6 days ago
Select Alaska Airlines flight, departing Tue, 16 Jun from New Orleans to Tupelo, returning Tue, 23 Jun, priced at £926 found 6 days ago
Alaska Airlines
Fri, 5 Jun - Thu, 11 Jun
MSY
New Orleans
TUP
Tupelo
£953 Return, found 2 days ago
£953
Return
found 2 days ago
Select Alaska Airlines flight, departing Fri, 5 Jun from New Orleans to Tupelo, returning Thu, 11 Jun, priced at £953 found 2 days ago
Alaska Airlines
Fri, 5 Jun - Thu, 11 Jun
MSY
New Orleans
TUP
Tupelo
£956 Return, found 22 hours ago
£956
Return
found 22 hours ago
Select Alaska Airlines flight, departing Fri, 5 Jun from New Orleans to Tupelo, returning Thu, 11 Jun, priced at £956 found 22 hours ago
Alaska Airlines
Fri, 5 Jun - Thu, 11 Jun
MSY
New Orleans
TUP
Tupelo
£979 Return, found 2 days ago
£979
Return
found 2 days ago
Select Alaska Airlines flight, departing Fri, 5 Jun from New Orleans to Tupelo, returning Thu, 11 Jun, priced at £979 found 2 days ago
Alaska Airlines
Fri, 5 Jun - Thu, 11 Jun
MSY
New Orleans
TUP
Tupelo
£981 Return, found 22 hours ago
£981
Return
found 22 hours ago
Select Alaska Airlines flight, departing Fri, 5 Jun from New Orleans to Tupelo, returning Thu, 11 Jun, priced at £981 found 22 hours ago

Frequently asked questions

How do I find cheap flights from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional)?
To find a cheap flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional)?
There are approximately 8 connecting flights per day from Louis Armstrong New Orleans Intl. (MSY) to Tupelo Regional (TUP). Some common connection points include George Bush Intercontinental (IAH), Dallas-Fort Worth Intl. (DFW), and O'Hare Intl. (ORD).
What is the earliest flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional)?
The earliest flight from Louis Armstrong New Orleans International Airport (MSY) to Tupelo Regional (TUP) typically departs at approximately 7:00 AM local time, operated by United Airlines and Contour Airlines. This is a seasonal service active in June. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional)?
A flight from MSY to TUP with a layover takes around 9 hours 30 minutes, with the route covering approximately 308 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional)?
Select the "Business class" and "First class" filters when looking for MSY to TUP flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional) flight with Expedia?
It's easy to earn miles on a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Tupelo from Louis Armstrong New Orleans Intl. (MSY)?
From Louis Armstrong New Orleans Intl. (MSY), you can fly into Tupelo Regional (TUP) to reach Tupelo. Some flights may connect through major hubs like George Bush Intercontinental (IAH) before reaching Tupelo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional) at the last minute?
Typically, booking a last minute flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional) flight and hotel package?
Securing a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional)?
If you booked your New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Tupelo, MS (TUP-Tupelo Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
Tupelo Regional
Return price
£918
Distance
493 km

Book with confidence

Compare flights from New Orleans to Tupelo easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from New Orleans to Tupelo. Operating between them flights per day, 7 airlines cover the route. And fly direct, getting you to Tupelo Regional in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Louis Armstrong New Orleans Intl. to Tupelo Regional.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Louis Armstrong New Orleans Intl. (MSY) to Tupelo Regional (TUP)

The easiest way to view the best deals on flights from New Orleans to Tupelo today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Louis Armstrong New Orleans Intl. to Tupelo Regional start at just £919 and range up to £981.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near New Orleans and Tupelo
  • booking your flight during June, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your New Orleans to Tupelo flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Louis Armstrong New Orleans Intl. to Tupelo Regional for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from New Orleans to Tupelo easily and book with confidence

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