A cityscape with a prominent dome structure and skyscrapers against a sunset sky.

£278 Cheap Flights from Medellín (MDE) to Los Angeles (LAX)

View £278 flight on Wed, 11 Nov 2026Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Los Angeles Intl. (LAX)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 25% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Medellín (MDE) to Los Angeles (LAX)

Prices were available within the past 7 days and start at £278 for one-way flights and £512 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, 30 Oct - Sun, 8 Nov
MDE
Medellín
LAX
Los Angeles
£512 Return, found 6 days ago
£512
Return
found 6 days ago
Select Copa flight, departing Fri, 30 Oct from Medellín to Los Angeles, returning Sun, 8 Nov, priced at £512 found 6 days ago
LATAM Airlines Group
Fri, 30 Oct - Sun, 8 Nov
MDE
Medellín
LAX
Los Angeles
£517 Return, found 6 days ago
£517
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, 30 Oct from Medellín to Los Angeles, returning Sun, 8 Nov, priced at £517 found 6 days ago
avianca
Tue, 18 Aug - Mon, 31 Aug
MDE
Medellín
LAX
Los Angeles
£517 Return, found 2 days ago
£517
Return
found 2 days ago
Select avianca flight, departing Tue, 18 Aug from Medellín to Los Angeles, returning Mon, 31 Aug, priced at £517 found 2 days ago
JetBlue Airways
Fri, 30 Oct - Sun, 8 Nov
MDE
Medellín
LAX
Los Angeles
£527 Return, found 6 days ago
£527
Return
found 6 days ago
Select JetBlue Airways flight, departing Fri, 30 Oct from Medellín to Los Angeles, returning Sun, 8 Nov, priced at £527 found 6 days ago
avianca
Sun, 23 Aug - Sun, 30 Aug
MDE
Medellín
LAX
Los Angeles
£531 Return, found 3 days ago
£531
Return
found 3 days ago
Select avianca flight, departing Sun, 23 Aug from Medellín to Los Angeles, returning Sun, 30 Aug, priced at £531 found 3 days ago
LATAM Airlines Group
Fri, 26 Feb - Sat, 27 Mar
MDE
Medellín
LAX
Los Angeles
£535 Return, found 4 days ago
£535
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 26 Feb from Medellín to Los Angeles, returning Sat, 27 Mar, priced at £535 found 4 days ago
avianca
Fri, 21 Aug - Sun, 23 Aug
MDE
Medellín
LAX
Los Angeles
£536 Return, found 6 days ago
£536
Return
found 6 days ago
Select avianca flight, departing Fri, 21 Aug from Medellín to Los Angeles, returning Sun, 23 Aug, priced at £536 found 6 days ago
LATAM Airlines Group
Fri, 26 Feb - Sat, 27 Mar
MDE
Medellín
LAX
Los Angeles
£540 Return, found 4 days ago
£540
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 26 Feb from Medellín to Los Angeles, returning Sat, 27 Mar, priced at £540 found 4 days ago
avianca
Mon, 24 Aug - Sun, 30 Aug
MDE
Medellín
LAX
Los Angeles
£544 Return, found 3 days ago
£544
Return
found 3 days ago
Select avianca flight, departing Mon, 24 Aug from Medellín to Los Angeles, returning Sun, 30 Aug, priced at £544 found 3 days ago
United
Sun, 23 Aug - Sun, 30 Aug
MDE
Medellín
LAX
Los Angeles
£692 Return, found 3 days ago
£692
Return
found 3 days ago
Select United flight, departing Sun, 23 Aug from Medellín to Los Angeles, returning Sun, 30 Aug, priced at £692 found 3 days ago

Frequently asked questions

How much does a flight from Medellín (MDE-José María Córdova Intl.) to Los Angeles, CA (LAX-Los Angeles Intl.) cost?
You can find one-way and return flights from MDE to LAX with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when MDE to LAX ticket fares go up or down.
What is the cheapest month to fly from Medellín (MDE-José María Córdova Intl.) to Los Angeles, CA (LAX-Los Angeles Intl.)?
September is typically the cheapest month to fly from Medellín (MDE-José María Córdova Intl.) to Los Angeles, CA (LAX-Los Angeles Intl.), with average return fares around £387. September often sees lower prices as the peak summer travel season winds down, leading to reduced demand. Other cheap months to fly from Medellín (MDE) to Los Angeles (LAX) include October and November.
Which airlines fly direct from Medellín (MDE) to Los Angeles, CA (LAX)?
Enter MDE to LAX and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Medellín (MDE) to Los Angeles, CA (LAX)?
To find a cheap flight from Medellín (MDE)Los Angeles, CA (LAX), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Medellín (MDE) to Los Angeles, CA (LAX)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Medellín (MDE) to Los Angeles, CA (LAX)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from Medellín (MDE) to Los Angeles, CA (LAX). To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Medellín (MDE-José María Córdova Intl.) to Los Angeles, CA (LAX-Los Angeles Intl.)?
A flight from MDE to LAX with a layover takes around 15 hours 30 minutes, with the route covering approximately 5,386 kilometers. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Medellín (MDE) to Los Angeles, CA (LAX)?
Select the "Business class" and "First class" filters when looking for Medellín (MDE) to Los Angeles, CA (LAX) flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Medellín (MDE) to Los Angeles, CA (LAX) flight with Expedia?
It's easy to earn miles on a It'Medellín (MDE)Los Angeles, CA (LAX) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
Is it cheaper to buy a plane ticket from Medellín (MDE) to Los Angeles, CA (LAX) at the last minute?
Typically, booking a last minute flight from Medellín (MDE)Los Angeles, CA (LAX) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Medellín (MDE) to Los Angeles, CA (LAX) flight and hotel package?
Securing a Medellín (MDE)Los Angeles, CA (LAX) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Medellín (MDE) to Los Angeles, CA (LAX)?
If you booked your Medellín (MDE)Los Angeles, CA (LAX) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Los Angeles Intl.
Airlines serving
Aeromexico, Copa, LATAM Airlines Group, avianca
Return price
£512
Distance
5354 km

Book with confidence

Compare flights from Medellín to Los Angeles easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Medellín to Los Angeles. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Los Angeles Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from José María Córdova Intl. to Los Angeles Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from José María Córdova Intl. (MDE) to Los Angeles Intl. (LAX)

The easiest way to view the best deals on flights from Medellín to Los Angeles today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from José María Córdova Intl. to Los Angeles Intl. start at just £512 and range up to £692.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Medellín and Los Angeles
  • booking your flight during October, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Medellín to Los Angeles flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from José María Córdova Intl. to Los Angeles Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Medellín to Los Angeles easily and book with confidence

Explore a world of travel with Expedia

*Available to Expedia members.