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£301 Cheap Flights from Lisbon (LIS) to San Francisco (SFO)

View £301 flight on Mon, 7 Dec 2026

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Popular airlines from Humberto Delgado Airport (LIS) to San Francisco International Airport (SFO)

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  • Cheap Flights from Lisbon to San Francisco (LIS-SFO)

    Prices were available within the past 7 days and start at £301 for one-way flights and £481 for return, for the period specified. Prices and availability are subject to change. Additional terms apply.

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    One way

    Return

    Select SAS flight, departing Wed, 3 Feb from Lisbon to San Francisco, returning Sat, 13 Feb, priced at £481 Found 2 days ago

    Wed, 3 Feb - Sat, 13 Feb · LIS · SFO · From £481 · Return

    Select SAS flight, departing Fri, 12 Feb from Lisbon to San Francisco, returning Sun, 28 Feb, priced at £486 Found 1 day ago

    Fri, 12 Feb - Sun, 28 Feb · LIS · SFO · From £486 · Return

    Select SAS flight, departing Wed, 10 Feb from Lisbon to San Francisco, returning Mon, 22 Feb, priced at £494 Found 11 hours ago

    Wed, 10 Feb - Mon, 22 Feb · LIS · SFO · From £494 · Return

    Select SAS flight, departing Tue, 22 Dec from Lisbon to San Francisco, returning Mon, 28 Dec, priced at £530 Found 5 days ago

    Tue, 22 Dec - Mon, 28 Dec · LIS · SFO · From £530 · Return

    Select SAS flight, departing Fri, 2 Apr from Lisbon to San Francisco, returning Mon, 26 Apr, priced at £533 Found 1 day ago

    Fri, 2 Apr - Mon, 26 Apr · LIS · SFO · From £533 · Return

    Select SAS flight, departing Sun, 22 Nov from Lisbon to San Francisco, returning Sun, 29 Nov, priced at £536 Found 4 days ago

    Sun, 22 Nov - Sun, 29 Nov · LIS · SFO · From £536 · Return

    Select Iberia flight, departing Wed, 10 Feb from Lisbon to San Francisco, returning Mon, 22 Feb, priced at £577 Found 11 hours ago

    Wed, 10 Feb - Mon, 22 Feb · LIS · SFO · From £577 · Return

    Select British Airways flight, departing Sat, 26 Dec from Lisbon to San Francisco, returning Wed, 30 Dec, priced at £581 Found 6 hours ago

    Sat, 26 Dec - Wed, 30 Dec · LIS · SFO · From £581 · Return

    Select KLM flight, departing Fri, 29 Jan from Lisbon to San Francisco, returning Sat, 6 Feb, priced at £590 Found 5 days ago

    Fri, 29 Jan - Sat, 6 Feb · LIS · SFO · From £590 · Return

    Select American Airlines flight, departing Fri, 9 Apr from Lisbon to San Francisco, returning Fri, 23 Apr, priced at £590 Found 3 days ago

    Fri, 9 Apr - Fri, 23 Apr · LIS · SFO · From £590 · Return

    Alternative airports near San Francisco

    Prices were available within the past 7 days. Prices and availability are subject to change.

    Select flight to San Francisco Intl. SFO. Cheapest and Closest option available. Average driving time to city centre is 19 minutes. Flights from £1,073

    19 min

    Find the cheapest month to fly from Lisbon (LIS) to San Francisco (SFO)

    January is typically the cheapest month to fly

    From £450 - £1,119 per traveller.

    View flights in January

    Insights are based on prices from searches for economy trips of 10 days or less on our sites in the last 12 months. Insights are informative only and current prices may differ.

    Book with confidence

    Compare flights from Lisbon to San Francisco easily and book with confidence

    For travelling on business or for pleasure, Expedia makes it easy to book your flights from Lisbon to San Francisco. Operating between them 1 flights per day, 11 airlines cover the route. And TAP Air Portugal fly direct, getting you to San Francisco Intl. in just 12hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Humberto Delgado to San Francisco Intl..

    To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.

    Grab a great deal on your flight from Humberto Delgado (LIS) to San Francisco Intl. (SFO)

    The easiest way to view the best deals on flights from Lisbon to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Humberto Delgado to San Francisco Intl. start at just £481 and range up to £590.

    To find an even better deal, try

    • being flexible on your dates – midweek flights can be cheaper
    • looking for other airports near Lisbon and San Francisco
    • booking your flight during February, the cheapest month on this route
    • varying your flight times – early morning and late at night are sometimes cheaper

    Why you should book your Lisbon to San Francisco flight with Expedia!

    We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Humberto Delgado to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.

    Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.

    Frequently Asked Questions

    How much does a flight from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) cost?

    You can find one-way and return flights from LIS to SFO with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when LIS to SFO ticket fares go up or down.

    What is the cheapest month to fly from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    If you're looking for the cheapest time to fly from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.), March is typically your best bet. You can expect average return flight prices around £552 during this month. Other budget-friendly months for this route include April and May.

    Which airlines fly direct from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    Only one airline offers direct flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.). TAP Portugal operates 7 direct flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) every week.

    What is the cheapest airline that flies from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    TAP Portugal is one of the cheapest airlines offering nonstop return flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.), with tickets starting from around £567 for flights that can be booked for departure within the next year. Transavia offers one of the cheapest connecting return flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) with a layover in Schiphol (AMS), starting from around £675. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.

    How do I find cheap flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    To find a cheap flight from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

    What is the best airline to fly with from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    The best airline to fly with from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) will differ from traveler to traveler. If you like to fly early, TAP Portugal offers early morning flights. If price is the most important factor, TAP Portugal typically offers the lowest fares. TAP Portugal offers the most daily flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.

    What is the best time to fly from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    When looking for the best time to fly from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.), it's a good idea to consider both price and popularity. The cheapest months to fly are typically March and May, with average return flights around £552. The most popular months for this route are September and July, which means you'll find plenty of flight options during these times. While there isn't a single month that is both the cheapest and most popular, if you're flexible, aiming for March or May could save you money, while September and July offer more choice for your travel plans.

    How many flights per day from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    While direct flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) are minimal, you'll find around 73 connecting flights per day. This gives you plenty of options to choose from. Some common connection points include Adolfo Suarez Madrid-Barajas (MAD), Dublin (DUB), and Heathrow (LHR).

    What is the earliest flight from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    The earliest flight from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) typically departs around 5:00 AM. This service is offered by airlines such as KLM and Air France. Please note that this is a seasonal service, active only in September. An early departure like this can be great for maximising your time in San Francisco. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

    What day of the week has the most flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    You'll typically find the most flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) on a Saturday, with around 62 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include TAP Portugal, Lufthansa, and British Airways. Saturdays offer notably more flight options compared to other days of the week, making it a convenient day to travel.

    What are the most popular departure times for flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    The most popular departure times for flights from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) are between 9am and 12pm. Many major carriers, including United, American Airlines and TAP Portugal, offer flights during this window. Many travellers prefer these times as they allow for a relaxed start to the day while still arriving at your destination at a reasonable hour.

    How long does it take to fly from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    A non-stop flight from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) typically takes around 12 hours 30 minutes. This journey covers a distance of approximately 9,123 kilometers. If you opt for a flight with one stop, your travel time will be longer, usually around 16 hours. Flights with two or more stops generally take even longer, with typical durations around 23 hours 30 minutes. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some flexibility in your travel plans.

    Can you fly business or first class from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    Yes, you can fly business class or first class between LIS and SFO. Airlines that offer business class service on this route include:

    * TAP Portugal
    * Swiss International Air Lines
    * Lufthansa
    * Air France
    * Iberia
    * Turkish Airlines
    * Air Europa
    * KLM
    * Emirates
    * SAS
    * Icelandair
    * Brussels Airlines
    * LOT-Polish Airlines
    * British Airways
    * (multiple carriers)
    * Air Canada
    * United
    * Delta
    * Portugalia
    * American Airlines

    First class cabins are available on Emirates.

    How do I earn miles on a Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) flight with Expedia?

    It's easy to earn miles on a Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.

    *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

    What airports do you fly into for San Francisco, CA (SFO) from Lisbon (LIS)?

    If you're planning to travel to San Francisco from Humberto Delgado (LIS), you can fly directly into San Francisco Intl. (SFO). Some flights may connect through major hubs like Adolfo Suarez Madrid-Barajas (MAD), Heathrow (LHR), or Frankfurt Intl. (FRA) before reaching San Francisco. Compare routes and airports on Expedia to find the best flight options for your travel plans.

    Is it cheaper to buy a plane ticket from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) at the last minute?

    Typically, booking a last minute flight from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

    Is it cheaper to book a Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package?

    Securing a Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

    Can I cancel or change the date of my flight from Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.)?

    If you booked your Lisbon (LIS-Humberto Delgado) to San Francisco, CA (SFO-San Francisco Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

    Travel information

    Origin airportHumberto Delgado Airport
    Destination airportSan Francisco International Airport
    Distance5,668 miles away
    Airlines servingBrussels Airlines, British Airways, Lufthansa, Air Canada, TAP Portugal, Swiss International Air Lines, SAS, KLM, Finnair, Turkish Airlines, Air France, Aer Lingus, Virgin Atlantic, American Airlines, Delta, ITA Airways, JetBlue Airways, Iberia, United, Air Europa, Alaska Airlines, LOT-Polish Airlines, Emirates, Icelandair
    Popular airlineBrussels Airlines
    Return price£481
    Average flight time12 hours 48 mins

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