£460 Cheap Flights from Des Moines (DSM) to Venice (VCE)

View £460 flight on Thu, 3 Sept 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Marco Polo Airport (VCE)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 25% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Des Moines (DSM) to Venice (VCE)

Prices were available within the past 7 days and start at £460 for one-way flights and £956 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Mon, 8 Jun - Mon, 15 Jun
DSM
Des Moines
VCE
Venice
£956 Return, found 4 days ago
£956
Return
found 4 days ago
Select Air Canada flight, departing Mon, 8 Jun from Des Moines to Venice, returning Mon, 15 Jun, priced at £956 found 4 days ago
Iberia
Wed, 10 Jun - Wed, 17 Jun
DSM
Des Moines
VCE
Venice
£958 Return, found 2 days ago
£958
Return
found 2 days ago
Select Iberia flight, departing Wed, 10 Jun from Des Moines to Venice, returning Wed, 17 Jun, priced at £958 found 2 days ago
Air France
Sat, 6 Jun - Sat, 13 Jun
DSM
Des Moines
VCE
Venice
£998 Return, found 5 days ago
£998
Return
found 5 days ago
Select Air France flight, departing Sat, 6 Jun from Des Moines to Venice, returning Sat, 13 Jun, priced at £998 found 5 days ago
Air France
Sat, 6 Jun - Sat, 13 Jun
DSM
Des Moines
VCE
Venice
£1,007 Return, found 5 days ago
£1,007
Return
found 5 days ago
Select Air France flight, departing Sat, 6 Jun from Des Moines to Venice, returning Sat, 13 Jun, priced at £1,007 found 5 days ago
Iberia
Thu, 11 Jun - Thu, 18 Jun
DSM
Des Moines
VCE
Venice
£1,010 Return, found 1 day ago
£1,010
Return
found 1 day ago
Select Iberia flight, departing Thu, 11 Jun from Des Moines to Venice, returning Thu, 18 Jun, priced at £1,010 found 1 day ago
Iberia
Thu, 11 Jun - Thu, 18 Jun
DSM
Des Moines
VCE
Venice
£1,018 Return, found 1 day ago
£1,018
Return
found 1 day ago
Select Iberia flight, departing Thu, 11 Jun from Des Moines to Venice, returning Thu, 18 Jun, priced at £1,018 found 1 day ago
Air France
Wed, 10 Jun - Wed, 17 Jun
DSM
Des Moines
VCE
Venice
£1,026 Return, found 2 days ago
£1,026
Return
found 2 days ago
Select Air France flight, departing Wed, 10 Jun from Des Moines to Venice, returning Wed, 17 Jun, priced at £1,026 found 2 days ago
Air France
Mon, 8 Jun - Mon, 15 Jun
DSM
Des Moines
VCE
Venice
£1,033 Return, found 4 days ago
£1,033
Return
found 4 days ago
Select Air France flight, departing Mon, 8 Jun from Des Moines to Venice, returning Mon, 15 Jun, priced at £1,033 found 4 days ago
KLM
Sat, 6 Jun - Sat, 13 Jun
DSM
Des Moines
VCE
Venice
£1,039 Return, found 5 days ago
£1,039
Return
found 5 days ago
Select KLM flight, departing Sat, 6 Jun from Des Moines to Venice, returning Sat, 13 Jun, priced at £1,039 found 5 days ago
Virgin Atlantic
Sat, 6 Jun - Sat, 13 Jun
DSM
Des Moines
VCE
Venice
£1,044 Return, found 5 days ago
£1,044
Return
found 5 days ago
Select Virgin Atlantic flight, departing Sat, 6 Jun from Des Moines to Venice, returning Sat, 13 Jun, priced at £1,044 found 5 days ago

Frequently asked questions

How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
There are approximately 37 connecting flights per day from Des Moines Intl. (DSM) to Marco Polo (VCE). Some common connection points include O'Hare Intl. (ORD), Hartsfield-Jackson Atlanta Intl. (ATL), and Minneapolis - St. Paul Intl. (MSP).
What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
The earliest flight from Des Moines Intl. (DSM) to Marco Polo (VCE) typically departs at approximately 5:00 AM local time. This service is operated by American Airlines and British Airways. This is a seasonal service, active only in May. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
You'll typically find the most flights from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) on a Thursday, with around 44 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Delta Air Lines, American Airlines, and United Airlines.
What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
The most popular departure times for flights from Des Moines Intl. (DSM) to Marco Polo (VCE) are in the afternoon, from 3pm to 6pm. About 23% of passengers prefer this time. Many major carriers, including United Airlines, Delta Air Lines and Lufthansa, offer flights during this window. This timing works well because it allows you to have a productive morning before heading to the airport, and you'll arrive at your destination ready to settle in for the evening.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
Flights from DSM to VCE with one stop typically take around 20 hours 20 minutes, covering approximately 4,894 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
Select the "Business class" and "First class" filters when looking for DSM to VCE flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) flight with Expedia?
It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Venice from Des Moines Intl. (DSM)?
If you're planning to travel to Venice from Des Moines Intl. (DSM), you can fly directly into Marco Polo (VCE) Some flights may connect through major hubs like O'Hare Intl. (ORD), Hartsfield-Jackson Atlanta Intl. (ATL), Denver Intl. (DEN) before reaching Venice. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) at the last minute?
Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) flight and hotel package?
Securing a Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo)?
If you booked your Des Moines, IA (DSM-Des Moines Intl.) to Venice (VCE-Marco Polo) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Marco Polo
Airlines serving
Air Canada, Air France, British Airways, Iberia, KLM, Lufthansa
Return price
£955
Distance
7829 km

Book with confidence

Compare flights from Des Moines to Venice easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Des Moines to Venice. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Marco Polo in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Des Moines Intl. to Marco Polo.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Des Moines Intl. (DSM) to Marco Polo (VCE)

The easiest way to view the best deals on flights from Des Moines to Venice today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Des Moines Intl. to Marco Polo start at just £956 and range up to £1,044.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Des Moines and Venice
  • booking your flight during June, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Des Moines to Venice flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Des Moines Intl. to Marco Polo for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Des Moines to Venice easily and book with confidence

Explore a world of travel with Expedia

*Available to Expedia members.