Title: Cheap Flights from Des Moines to Fort Myers (DSM to RSW) - Expedia.co.uk ![](https://images.trvl-media.com/place/602729/4a41b6c1-70b7-400e-acce-ff7dd08a876f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/602729/4a41b6c1-70b7-400e-acce-ff7dd08a876f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Des Moines (DSM) to Fort Myers (RSW) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Des Moines International Airport (DSM) to Southwest Florida Intl. Airport (RSW) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:rsw,departure:29/09/2025TANYT&leg2=from:rsw,to:dsm,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:rsw,departure:29/09/2025TANYT&leg2=from:rsw,to:dsm,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:rsw,departure:29/09/2025TANYT&leg2=from:rsw,to:dsm,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:rsw,departure:29/09/2025TANYT&leg2=from:rsw,to:dsm,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Find the cheapest month to fly from Des Moines (DSM) to Fort Myers (RSW) ### August is typically the cheapest month to fly From £141 - £502 per traveller. Flight from Des Moines to Fort Myers route information | Origin airport | Des Moines Intl. | | --- | --- | | Destination airport | Southwest Florida Intl. | | Distance | 1980 km | ## Compare flights from Des Moines to Fort Myers easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Des Moines to Fort Myers. Operating between them flights per day, airlines cover the route. And fly direct, getting you to Southwest Florida Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Des Moines Intl. to Southwest Florida Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Des Moines Intl. (DSM) to Southwest Florida Intl. (RSW) The easiest way to view the best deals on flights from Des Moines to Fort Myers today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Des Moines Intl. to Southwest Florida Intl. start at just and range up to .   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Des Moines and Fort Myers - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Des Moines to Fort Myers flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Des Moines Intl. to Southwest Florida Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Frequently asked questions ### How much is a flight from DSM to Southwest Florida Intl. Airport (RSW)? > Round-trip tickets from Des Moines Intl. Airport (DSM) to Southwest Florida Intl. Airport start from . This price is based on fares offered within the last 7 days on Expedia for flights departing within the next year — book now so you don't miss out. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Des Moines Intl. Airport to RSW? > The majority of flights can be cancelled online, but every air carrier has a different set of terms and conditions. If you do have to cancel your flight, go to our [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033) and follow the instructions. ### How do I find cheap flights from Des Moines Intl. Airport (DSM) to RSW that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Des Moines Intl. Airport (DSM) to Southwest Florida Intl. Airport flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from Des Moines Intl. Airport (DSM) to Southwest Florida Intl. Airport (RSW)? > Expect to be cruising at altitude for a while, as the flight distance between Des Moines Intl. Airport and Southwest Florida Intl. Airport is 2,000 kilometres. Create a playlist of your favourite songs before leaving home to stay entertained during your journey. ### Which airlines fly direct from Des Moines Intl. Airport to RSW? > Unfortunately, there are no airlines that fly directly between Des Moines Intl. Airport (DSM) and Southwest Florida Intl. Airport (RSW). You'll have to book a flight with at least one stop. ### Are Des Moines Intl. Airport to Southwest Florida Intl. Airport (RSW) flight tickets cheaper when they're purchased at the last minute? > Last-minute planners can occasionally score a bargain, with some of the cheapest airfares from Des Moines Intl. Airport (DSM) to Southwest Florida Intl. Airport (RSW) appearing a few weeks prior to the departure date. If you'd rather book ahead, Expedia compares and updates the best flight deals continuously — as early as a year in advance in some cases. It depends on the carrier though, as not every airline releases prices that far in advance. ## Explore a world of travel with Expedia - Trending Routes - Trending Flights - Top Flights Destinations - Related Airlines - Cheap Flights from Other Airports - Expedia's Latest Trends ### Top Routes from Des Moines - [Des Moines to Paris (DSM - CDG)](https://expedia.co.uk/lp/flights/dsm/cdg/des-moines-to-paris) - [Des Moines to London (DSM - LHR)](https://expedia.co.uk/lp/flights/dsm/lhr/des-moines-to-london) - [Des Moines to Manchester (DSM - MAN)](https://expedia.co.uk/lp/flights/dsm/man/des-moines-to-manchester) ### Top Routes to Fort Myers - [Newark Liberty Intl. 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