Cheap Flights from Los Santos from £262

View £139 flight on Tue, 1 Dec 2026

Popular airlines from Los Santos

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 25% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards

    Sign in

  • Cheapest flights from Los Santos

    Prices were available within the past 7 days and start at £262 for one-way flights and £290 for return, for the period specified. Prices and availability are subject to change. Additional terms apply.

    All deals

    One way

    Return

    Select Avianca flight, departing Mon, 14 Dec from Panama City to Bogotá, returning Mon, 14 Dec, priced at £290 Found 4 days ago

    Mon, 14 Dec - Mon, 14 Dec · PTY · BOG · From £290 · Return

    Select Avianca flight, departing Fri, 4 Dec from Panama City to Bogotá, returning Mon, 7 Dec, priced at £292 Found 9 hours ago

    Fri, 4 Dec - Mon, 7 Dec · PTY · BOG · From £292 · Return

    Select Avianca flight, departing Sat, 21 Nov from Panama City to Bogotá, returning Sun, 22 Nov, priced at £294 Found 3 hours ago

    Sat, 21 Nov - Sun, 22 Nov · PTY · BOG · From £294 · Return

    Select Avianca flight, departing Fri, 20 Nov from Panama City to Bogotá, returning Mon, 23 Nov, priced at £296 Found 5 days ago

    Fri, 20 Nov - Mon, 23 Nov · PTY · BOG · From £296 · Return

    Select Avianca flight, departing Sat, 21 Nov from Panama City to Bogotá, returning Sun, 22 Nov, priced at £300 Found 3 hours ago

    Sat, 21 Nov - Sun, 22 Nov · PTY · BOG · From £300 · Return

    Select Avianca flight, departing Sat, 21 Nov from Panama City to Bogotá, returning Sun, 22 Nov, priced at £301 Found 3 hours ago

    Sat, 21 Nov - Sun, 22 Nov · PTY · BOG · From £301 · Return

    Select Copa flight, departing Sun, 31 Jan from Panama City to Bogotá, returning Sat, 13 Feb, priced at £309 Found 4 days ago

    Sun, 31 Jan - Sat, 13 Feb · PTY · BOG · From £309 · Return

    Select United flight, departing Tue, 17 Nov from Panama City to Ontario, returning Tue, 24 Nov, priced at £592 Found 4 days ago

    Tue, 17 Nov - Tue, 24 Nov · PTY · ONT · From £592 · Return

    Select American Airlines flight, departing Tue, 24 Nov from Panama City to Los Angeles, returning Tue, 1 Dec, priced at £599 Found 7 hours ago

    Tue, 24 Nov - Tue, 1 Dec · PTY · LAX · From £599 · Return

    Select Air Europa flight, departing Wed, 23 Dec from Panama City to Amsterdam, returning Thu, 31 Dec, priced at £607 Found 7 hours ago

    Wed, 23 Dec - Thu, 31 Dec · PTY · AMS · From £607 · Return

    How to Find Cheap Flights from Los Santos

    How much is a flight from Los Santos?

    This week, flights from Los Santos are available between £290–£607.

    How to find cheap flights from Los Santos?

    Expedia makes it easy to compare cheap flights from Los Santos to many destinations. Check out excellent deals on both domestic and international flights from Los Santos. Once you select an offer, use our filters and sort by “ Price (Lowest)” to see the cheapest and most suitable options.

    How can I get the best deal on flights from Los Santos?

    Expedia gives you access to all the hottest deals on plane tickets so you can get the most amount of value for the lowest price possible. An excellent strategy for finding the best deal on flights is to be flexible with your dates. For each offer, you can compare prices for similar time frames using our “Show flexible dates” feature. Depending on your destination, direct flights from Los Santos may be more expensive. Airlines with strict bag policies or fees can also impact your costs.

    What is the best airline to fly from Los Santos?

    At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Los Santos with: Avianca, Copa, United, American Airlines, Aeromexico, Air Europa.

    What is the best month to fly from Los Santos?

    Prices on plane tickets vary considerably throughout the year due to seasonal demand. Historically, the cheapest time to buy flights from Los Santos airport(s) is December.

    When is the best time to book flights from Los Santos?

    ARC & Expedia Group historical data suggests that booking flights three weeks before departure and on a weekend, usually on a Sunday, can save you up to 20% on your fare. *

    Are there any last-minute flights from Los Santos?

    Expedia is the place to find last-minute flights from Los Santos, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source the best deals for you and display the best offers available over the next two weeks.

    Why book with Expedia?

    Booking flights from Los Santos with Expedia is the obvious choice to get low prices, save money and see more value for every pound spent. We show you the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from. You can customise your journey to your timeline, route preferences, budget, rewards programmes and more. Not only will you get a stellar deal, but you’ll also get rewards points back and the opportunity for additional discounts when bundling with a hotel or car hire.

    Can I change/cancel my flight?

    Some flights can be changed or cancelled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our customer service portal. We recommend choosing flights with no change fees for maximum flexibility. Filter by “Flexible change policies” to see flights with no change fees.

    Travel information

    Airlines servingAvianca, United, American Airlines, Copa, Delta, Aeromexico, Turkish Airlines, KLM, Air France, Iberia, Air Europa, Lufthansa, EVA Airways, Korean Air, Qatar Airways, GOL Linhas Aereas S.A., Emirates, Etihad Airways, WestJet, China Eastern Airlines, Cayman Airways, Caribbean Airlines, EL AL Israel Airlines
    Popular airlineAvianca
    Return price£262

    Explore a world of travel with Expedia

    *Available to Expedia members.