A historic building with ornate architecture and a modern brick structure in the foreground.

Find luxury hotels in Uptown, OH

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Uptown Luxury Hotels

Tonight
6 Sept - 7 Sept
Tomorrow
7 Sept - 8 Sept
Next weekend
11 Sept - 13 Sept
In two weeks
18 Sept - 20 Sept

Our top choices for Uptown luxury hotels

A bar area with a checkered ceiling, colorful hanging lights, and a neon sign in the background.
A reception area with a coffee machine, a display of pencils, and a sign reading "POINDEXTER".
A multi-story hotel with a brick facade, large windows, and a landscaped courtyard.
A modern living room with a round table, colorful chairs, a sofa, and a TV.

1. Graduate by Hilton Cincinnati

Graduate by Hilton Cincinnati
Corryville
£130
includes taxes & fees
13 Sept - 14 Sept
Graduate by Hilton Cincinnati
A modern outdoor seating area with a fire feature, surrounded by black wicker chairs and teal cushions, overlooking a cityscape at sunset.
A modern bar area with white and teal chairs, a red-framed table, and a view of a cityscape at dusk.
A modern bar area with a long counter, multiple stools, and a large TV screen.
A modern lobby with grey upholstered seating, wooden paneling, and large windows.

2. Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel

Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel
Cincinnati
£134
includes taxes & fees
27 Sept - 28 Sept
Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel
A dining area with wooden tables and chairs, a wine cellar with wine racks, and a seating area with cushioned sofas.
A hotel room with a wooden headboard, a bedside lamp, a laptop, and a framed picture on the wall.
A table with a glass of orange juice on a balcony overlooking a cityscape with buildings and a tower.
A large banquet hall with round tables, black chairs, and white tablecloths.

3. 21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
Downtown Cincinnati
  • Artful luxury awaits at 21c Museum Hotel Cincinnati, where spa treatments and elevated dining complement the boutique atmosphere.
£138
includes taxes & fees
27 Sept - 28 Sept
21c Museum Hotel Cincinnati
A bar area with a television screen, bar stools, and a variety of bottles and glasses.
A set of three arched bookshelves with decorative items and books, set against a plain wall.
A lobby with a reception desk, a seating area with orange sofas, and a patterned carpet.
An indoor swimming pool with clear glass walls, a pool lift, and a lifeguard station.

4. voco The Clair Cincinnati Downtown by IHG

voco The Clair Cincinnati Downtown by IHG
Downtown Cincinnati
£123
includes taxes & fees
5 Oct - 6 Oct
voco The Clair Cincinnati Downtown by IHG
A rooftop terrace with outdoor seating, a fire pit, and string lights.
A modern bar area with a long counter, multiple bar stools, and hanging pendant lights.
A reception area with a marble counter, a decorative ceiling, and hanging light fixtures.
A spacious lobby with a modern design, featuring a seating area with sofas and chairs, a dining area with tables, and a kitchen in the background.

5. AC Hotel by Marriott Cincinnati at The Banks

AC Hotel by Marriott Cincinnati at The Banks
Downtown Cincinnati
£158
includes taxes & fees
27 Sept - 28 Sept
AC Hotel by Marriott Cincinnati at The Banks
A grand hall with ornate chandeliers, a central staircase, and a seating area with patterned upholstery.
An ornate chandelier in a grand hall with high ceilings and detailed wall carvings.
A luxurious hotel lobby with a bar, seating areas, and a grand staircase.
A luxurious hotel lobby with ornate wood paneling, a central bar area, and multiple seating arrangements.

6. Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza
Downtown Cincinnati
  • Historic hotel near Great American Ball Park combines pillowtop luxury, fine dining, and city centre Cincinnati charm.
£113
includes taxes & fees
27 Sept - 28 Sept
Hilton Cincinnati Netherland Plaza
A spacious lobby with a high ceiling, modern lighting fixtures, and a central staircase.
A hotel with a prominent 'HYATT' sign, modern glass facade, and a classic brick building nearby.
A modern hotel room with a sectional sofa, a round coffee table, a desk with a chair, and large windows offering a city view.
A spacious lobby with a reception desk, seating area, and large windows.

7. Hyatt Regency Cincinnati

Hyatt Regency Cincinnati
Downtown Cincinnati
  • Elegant riverside oasis in Cincinnati features premium design, plush bedrooms, and access to sports venues.
£137
includes taxes & fees
27 Sept - 28 Sept
Hyatt Regency Cincinnati
A multi-level atrium with glass railings, a high ceiling with metal beams, and a lower level with round tables and chairs.
A dining table set with white roses, wine glasses, and a statue in the background.
A spacious lobby with leather armchairs, sofas, and a central coffee table. A wine bar and lounge area is visible in the background.
A modern hotel lobby with a large sofa, a coffee table, and a dining area. There are potted plants and a large window offering a view of the city.

8. The Westin Cincinnati

The Westin Cincinnati
Downtown Cincinnati
£145
includes taxes & fees
27 Sept - 28 Sept
The Westin Cincinnati
A modern bar area with a long counter, bar stools, and a patterned wall.
A modern building with a large glass facade, the name "KINLEY" prominently displayed above the entrance.
A modern hotel room with a large window, a sofa, a small round table, and a wardrobe.
A modern restaurant interior with round tables, cushioned seating, pendant lighting, and a large window with a view.

9. Kinley Cincinnati Downtown, a Tribute Portfolio Hotel

Kinley Cincinnati Downtown, a Tribute Portfolio Hotel
Downtown Cincinnati
£158
includes taxes & fees
25 Sept - 26 Sept
Kinley Cincinnati Downtown, a Tribute Portfolio Hotel
A historic building with multiple stories, large windows, and a prominent entrance with a neon sign.
A rooftop terrace with glass enclosures, seating areas, and a view of the city skyline.
A bar area with a wooden bench and stools, a patterned rug, and a ceiling with circular light fixtures.
A modern hotel room with exposed brick walls, a large bed with a TV, a sofa, and a small table.

10. Moxy Cincinnati Downtown

Moxy Cincinnati Downtown
Downtown Cincinnati
£152
includes taxes & fees
27 Sept - 28 Sept
Moxy Cincinnati Downtown
View all properties

Top Uptown Hotel Reviews

Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

8/10 Good
"Rooms were good sized and very comfy. Carpets are pretty stained. Looks like people have been rough on them. Wanted to have a night cap, but bar area was full and they werent allowing add people there. Very happy with our stay. Wish there was a mircrowave."
Victoria 1-night trip
Posted less than an hour ago
Hilton Cincinnati Netherland Plaza
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

8/10 Good
"Great hotel! Very clean, comfy beds. Great location. Only reason I gave it 4 stars and it’s an individual preference but you have to request if you’d like a refrigerator in the room and same for ice and ice bin. Very minor just an inconvenience. Other than that it’s a wonderful hotel!"
Lea 2-night trip
Posted 2 hours ago
21c Museum Hotel Cincinnati
Hyatt Regency Cincinnati

Hyatt Regency Cincinnati

10/10 Excellent
"Great location. Walking proximity to Great American Ballpark. Would stay here again for sure. Staff were friendly and helpful."
MaryJane 2-night trip
Posted 3 hours ago
Hyatt Regency Cincinnati
The Westin Cincinnati

The Westin Cincinnati

10/10 Excellent
"Great place to stay for a Reds game. Close to restaurants and attractions. Room was great and they offered an upgrade at check in. Carpets seemed to be pretty dirty but everything else was clean. Staff was helpful and pleasant. We have stayed here twice now and would return."
Amy 1-night trip
Posted 4 hours ago
The Westin Cincinnati
Holiday Inn Express & Suites Cincinnati Riverfront by IHG

Holiday Inn Express & Suites Cincinnati Riverfront by IHG

10/10 Excellent
"Great location for our needs ."
George 2-night trip
Posted 8 hours ago
Holiday Inn Express & Suites Cincinnati Riverfront by IHG
Embassy Suites by Hilton Cincinnati RiverCenter

Embassy Suites by Hilton Cincinnati RiverCenter

10/10 Excellent
"Great stay! The front desk staff was super friendly and thorough at check-in. The hotel was clean and well maintained, and our room was a nice size with a microwave and refrigerator. The complimentary happy hour and breakfast were both great perks. Very convenient location for attending sporting events in Cincinnati—we would definitely stay here again!"
Rita 1-night trip
Posted 1 day ago
Embassy Suites by Hilton Cincinnati RiverCenter

Explore a world of travel with Expedia