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Our top choices for St. Charles hotels

1. Quality Inn & Suites Big Stone Gap

Quality Inn & Suites Big Stone Gap
2.5 star property
Big Stone Gap
9.4 out of 10, Exceptional, (537 reviews)
"If you don’t want to drive back into town for dinner and drinks , local taxi was $10 each way very reasonable (you’re on motorbikes so that was very handy)"
Canada
Donald
The price is £78
includes taxes & fees
9 Nov - 10 Nov
Quality Inn & Suites Big Stone Gap

2. Travel Inn - Duffield

Travel Inn - Duffield
2.0 star property
Duffield
7.8 out of 10, Good, (64 reviews)
"Nice check in, room was spotless"
United States
Joan
The price is £48
includes taxes & fees
27 Nov - 28 Nov
Travel Inn - Duffield

3. Quality Inn Harlan

Quality Inn Harlan
2.5 star property
Harlan
8.6 out of 10, Excellent, (396 reviews)
"Great place"
United States
Cristopher
The price is £74
includes taxes & fees
19 Nov - 20 Nov
Quality Inn Harlan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Frequently asked questions

What is the best area to stay in St Charles?
The best area to stay in St Charles is the historic Main Street district, which runs parallel to the Missouri River.

This area is the heart of St Charles, known for its beautifully preserved brick buildings, gas lamps, and cobblestone streets. Main Street itself is pedestrian-friendly, lined with independent shops, art galleries, and a variety of restaurants. It's a very walkable area, stretching from the First State Capitol Building on the north end to the Lewis & Clark Boat House and Museum towards the south.

Couples often find this area great for a relaxing getaway. You can enjoy strolls along the riverfront, explore the numerous unique boutiques, and dine at charming restaurants, many of which offer outdoor seating. The evening entertainment, including live music venues, is also easily accessible.

For those interested in history and exploring on foot, staying close to Main Street is ideal. You're within easy reach of historic sites like the Boone's Lick Road and the starting point of the Lewis and Clark expedition.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in St. Charles.
How much is the nightly rate at a St. Charles hotel?
Prices for hotels in St. Charles often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.