Title: TOP Business Hotels in Southwest, MS for 2026 | Expedia.co.uk [Southwest Travel Guide](https://expedia.co.uk/Southwest.dx6058704)[Hotels in Southwest](https://expedia.co.uk/Southwest-Hotels.d6058704.Travel-Guide-Hotels)[Holiday Rentals in Southwest](https://expedia.co.uk/Southwest-Holiday-Rentals.d6058704.Travel-Guide-HolidayRentals)[Flights to Southwest](https://expedia.co.uk/Cheap-Flights-To-Southwest.d6058704.Travel-Guide-Flights)[Things to do in Southwest](https://expedia.co.uk/Things-To-Do-In-Southwest.d6058704.Travel-Guide-Activities)[Southwest Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest.d6058704.Car-Hire-Guide)[Southwest Holidays](https://expedia.co.uk/Southwest.d6058704.Holidays-City-Breaks) ![Not the most spectacular photo but a very spectacular building and story. This 150-year-old house was never completed. The exterior incredibly magnificent but step inside and the top four floors… Or still in the same condition as when the craftsman left in 1865. Well worth the stop!](https://images.trvl-media.com/place/7671/fef4ceb3-3748-46c9-b2f8-73d43339f6b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Quentin White ![](https://images.trvl-media.com/place/7671/fef4ceb3-3748-46c9-b2f8-73d43339f6b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Business Hotels Tonight [4 Mar - 5 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-03-04&endDate=2026-03-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [5 Mar - 6 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-03-05&endDate=2026-03-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southwest business-friendly hotels ![Suite, 2 Queen Beds, Non Smoking | Pillow-top beds, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/910000/904600/904501/d7cc2167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/910000/904600/904501/3318a950.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/904600/904501/07d84202.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/910000/904600/904501/d83e80cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Brandon Amphitheater [](https://www.expedia.co.uk/Brandon-Hotels-Days-Inn-Suites-By-Wyndham-Brandon-Amphitheater.h904501.Hotel-Information) Brandon 9.0/10 Wonderful (42 reviews) "Great Staff and Friendly People. The staff welcomed us talked to us made us feel like home and Highly recommended and also, Please help them stay open and Expand Brandon, Mississippi needs this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mable £58 includes taxes & fees 11 Mar - 12 Mar [](https://www.expedia.co.uk/Brandon-Hotels-Days-Inn-Suites-By-Wyndham-Brandon-Amphitheater.h904501.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/ed94bf8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Oversized Room;with Sofabed) | Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/b17fee2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/844b8806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/a0e8ebfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Vicksburg [](https://www.expedia.co.uk/Vicksburg-Hotels-Best-Western-Vicksburg.h8071.Hotel-Information) Vicksburg 8.6/10 Excellent (1,006 reviews) "Th front desk staff was very friendly and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) heather £86 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Vicksburg-Hotels-Best-Western-Vicksburg.h8071.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/16000000/15140000/15137600/15137502/651bc62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/16000000/15140000/15137600/15137502/b22ad71f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15140000/15137600/15137502/3ec0073c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Mini fridge](https://images.trvl-media.com/lodging/16000000/15140000/15137600/15137502/80910be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Florence/Jackson Area [](https://www.expedia.co.uk/Jackson-Hotels-Days-Inn-Suites-By-Wyndham-FlorenceJackson-Area.h15137502.Hotel-Information) Florence 8.6/10 Excellent (967 reviews) "Everything about our stay was excellent… cleanliness, staff, breakfast was very adequate! We would definitely return." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Phil £64 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Jackson-Hotels-Days-Inn-Suites-By-Wyndham-FlorenceJackson-Area.h15137502.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/574d9394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/7253ac73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/588fa000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/8d2e7c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Natchez Grand Hotel & Suites On the River [](https://www.expedia.co.uk/Natchez-Hotels-Natchez-Grand-Hotel-Suites-On-The-River.h1788807.Hotel-Information) Natchez 8.6/10 Excellent (1,460 reviews) "Staff is always amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £94 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/Natchez-Hotels-Natchez-Grand-Hotel-Suites-On-The-River.h1788807.Hotel-Information) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2310000/2302900/2302829/da70e22e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds | In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/3000000/2310000/2302900/2302829/e0739c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2310000/2302900/2302829/39889223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2310000/2302900/2302829/9d24dd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites BYRAM by IHG [](https://www.expedia.co.uk/Jackson-Hotels-Holiday-Inn-Express-Hotel-Suites-BYRAM.h2302829.Hotel-Information) Byram 9.0/10 Wonderful (585 reviews) "Room nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £100 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Jackson-Hotels-Holiday-Inn-Express-Hotel-Suites-BYRAM.h2302829.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/28000000/27610000/27606400/27606328/066d5dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27610000/27606400/27606328/91872cc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/28000000/27610000/27606400/27606328/38da4901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/28000000/27610000/27606400/27606328/b319a907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Jackson Madison [](https://www.expedia.co.uk/Jackson-Hotels-Courtyard-By-Marriott-Jackson-Madison.h27606328.Hotel-Information) Madison 9.2/10 Wonderful (619 reviews) "Awesome hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy £88 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Jackson-Hotels-Courtyard-By-Marriott-Jackson-Madison.h27606328.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11900/11820/a4ea96d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11900/11820/d38b39f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11900/11820/97585963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/11900/11820/acfda3bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Vicksburg [](https://www.expedia.co.uk/Vicksburg-Hotels-Hampton-Inn-Suites-Vicksburg.h11820.Hotel-Information) Vicksburg 8.6/10 Excellent (869 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeanne £105 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Vicksburg-Hotels-Hampton-Inn-Suites-Vicksburg.h11820.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319420/e08048ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Accessible, Bathtub (Mobility & Hearing) | Living area | 50-inch Smart TV with satellite channels, Netflix, streaming services](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319420/16189beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319420/1a4a41c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319420/33634a95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Brandon [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Brandon-Jackson-Airport-E.h2319420.Hotel-Information) Brandon 7.4/10 Good (1,001 reviews) "Staff was great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph £61 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Brandon-Jackson-Airport-E.h2319420.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443721/6a247659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443721/3aa3e59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443721/7dcfc0fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Accessible, Non Smoking | Minibar, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443721/f94a1cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Vicksburg [](https://www.expedia.co.uk/Vicksburg-Hotels-Comfort-Suites-Vicksburg.h2443721.Hotel-Information) Vicksburg 8.6/10 Excellent (1,001 reviews) "Front desk was very welcoming!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krisha £95 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Vicksburg-Hotels-Comfort-Suites-Vicksburg.h2443721.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/27000000/26520000/26517900/26517860/40e30c7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26520000/26517900/26517860/aa6e4325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/27000000/26520000/26517900/26517860/1977c34f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/27000000/26520000/26517900/26517860/946ba366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Choctaw Hall Bed and Breakfast [](https://www.expedia.co.uk/Natchez-Hotels-Choctaw-Hall-Bed-And-Breakfast.h26517860.Hotel-Information) Natchez 10/10 Exceptional (352 reviews) "The staff was wonderful and accommodating and the rooms were a welcome change from hotels! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brinton [](https://www.expedia.co.uk/Natchez-Hotels-Choctaw-Hall-Bed-And-Breakfast.h26517860.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-18&endDate=2026-03-19®ionId=6058704&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6058704) ## Top Southwest Hotel Reviews ![Hilton Jackson](https://images.trvl-media.com/lodging/1000000/10000/1900/1845/c581281e_y.jpg) ### Hilton Jackson 10/10 Excellent "I was very impressed with the overall experience. The room was exceptionally clean, the amenities were well-maintained, and the staff was courteous and attentive throughout my stay." [](https://expedia.co.uk/Jackson-Hotels-Hilton-Jackson.h1845.Hotel-Information) ![Hyatt Place Jackson/ Ridgeland](https://images.trvl-media.com/lodging/3000000/2060000/2057700/2057647/49a9a419_y.jpg) ### Hyatt Place Jackson/ Ridgeland 10/10 Excellent "exceeded expectations! great value 😊" [](https://expedia.co.uk/Jackson-Hotels-Hyatt-Place-Jackson-Ridgeland.h2057647.Hotel-Information) ![Staybridge Suites Jackson by IHG](https://images.trvl-media.com/lodging/2000000/1250000/1246500/1246443/d3d3f5b6_y.jpg) ### Staybridge Suites Jackson by IHG 10/10 Excellent "I love everything nd I was well pleased " [](https://expedia.co.uk/Jackson-Hotels-Staybridge-Suites-Jackson.h1246443.Hotel-Information) ![Extended Stay America Select Suites Jackson North](https://images.trvl-media.com/lodging/1000000/80000/79500/79473/18a983a4_y.jpg) ### Extended Stay America Select Suites Jackson North 10/10 Excellent "I stayed here 9 months and I love staying at this hotel. The staff is very friendly and helpful. If I had to choose a hotel to stay at again ill pick this hotel again over everywhere else " [](https://expedia.co.uk/Jackson-Hotels-Extended-Stay-America-Suites-Jackson-North.h79473.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson Airport](https://images.trvl-media.com/lodging/1000000/570000/566700/566622/d4996108_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson Airport 10/10 Excellent "Room is spacious and clean. I had stayed here before as a pit stop and did so again this yr. Staff are courteous and nice, the lady at the front desk let me use the printer after I checked out. " [](https://expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Jackson-Airport.h566622.Hotel-Information) ![Riverwalk Casino Hotel](https://images.trvl-media.com/lodging/11000000/10970000/10967200/10967159/7010ce3a_y.jpg) ### Riverwalk Casino Hotel 10/10 Excellent "- Exceptionally clean room - Large comfortable room - Very comfortable bed with a quality mattress and pillows. - Quiet " [](https://expedia.co.uk/Vicksburg-Hotels-Riverwalk-Casino-Hotel.h10967159.Hotel-Information) ![Natchez Grand Hotel & Suites On the River](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/574d9394_y.jpg) ### Natchez Grand Hotel & Suites On the River 10/10 Excellent "Very nice staff, room was very clean and smelled great!!" [](https://expedia.co.uk/Natchez-Hotels-Natchez-Grand-Hotel-Suites-On-The-River.h1788807.Hotel-Information) ![The Westin Jackson](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/f28c478e_y.jpg) ### The Westin Jackson 10/10 Excellent "Excellent love the spa" [](https://expedia.co.uk/Jackson-Hotels-The-Westin-Jackson.h18411003.Hotel-Information) ![Prado Hotel](https://images.trvl-media.com/lodging/1000000/900000/891200/891169/3762baf1_y.jpg) ### Prado Hotel 10/10 Excellent "Shock! Dinner was included with drinks! That was a first for me! Clean hotel, nice staff. " [](https://expedia.co.uk/Jackson-Hotels-Drury-Inn-Suites-Jackson-Ridgeland.h891169.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Southwest cost? ### How many business hotels are there in Southwest? ### Why book your business hotel in Southwest with Expedia? ### How can I find cheap business hotels in Southwest? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [Bolton Hotels ](https://www.expedia.co.uk/Bolton-Hotels.d553248635975847266.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Brandon ](https://www.expedia.co.uk/Brandon-Hotels-Gay-Friendly-Hotel.0-0-d6754-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Brookhaven ](https://www.expedia.co.uk/Brookhaven-Hotels-Family-Friendly-Hotel.0-0-d7084-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Brookhaven ](https://www.expedia.co.uk/Brookhaven-Hotels-Gay-Friendly-Hotel.0-0-d7084-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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