Title: TOP Business Hotels in Sister Islands for 2025 | Expedia.co.uk [Sister Islands Travel Guide](https://expedia.co.uk/Sister-Islands.dx553248633946460050)[Hotels in Sister Islands](https://expedia.co.uk/Sister-Islands-Hotels.d553248633946460050.Travel-Guide-Hotels)[Holiday Rentals in Sister Islands](https://expedia.co.uk/Sister-Islands-Holiday-Rentals.d553248633946460050.Travel-Guide-HolidayRentals)[Flights to Sister Islands](https://expedia.co.uk/Cheap-Flights-To-Sister-Islands.d553248633946460050.Travel-Guide-Flights)[Sister Islands Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Sister-Islands.d553248633946460050.Car-Hire-Guide)[Sister Islands Holidays](https://expedia.co.uk/Sister-Islands.d553248633946460050.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/ee5503bbfc0fc8ae5ee4ab2cc68e9d52.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Sister Islands ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sister Islands Business Hotels Tonight [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248633946460050&startDate=2025-09-20&endDate=2025-09-21&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248633946460050&startDate=2025-09-21&endDate=2025-09-22&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248633946460050&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248633946460050&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sister Islands Business Hotels We don't have any properties that match your exact search [See all properties in Sister Islands](https://expedia.co.uk/Hotel-Search?startDate=2025-10-04&endDate=2025-10-05®ionId=553248633946460050&adults=2) ## Recommended hotels in Sister Islands ![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/72668cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/ed137e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach Club Studio | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/ec218d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Coast House | Living area](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/864ef166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Le Soleil d'Or CaymanBrac West End 9.4/10 Exceptional (13) "We love this property!! The service is outstanding and the staff is lovely. 100% recommend " £363 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/George-Town-Hotels-Le-Soleil-DOr-CaymanBrac.h74421869.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/45000000/44420000/44417600/44417537/bc8ab117.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/45000000/44420000/44417600/44417537/a5a10bf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/45000000/44420000/44417600/44417537/63ab8b1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/45000000/44420000/44417600/44417537/1fb3623a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Alexander Suites #101 - Queen Suite West End 9.4/10 Exceptional (6) "It is so accessible to the airport and other establishments like shops and grocery store." £202 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/West-End-Hotels-The-Alexander-Suites-101-Queen-Suite.h44417537.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/f420876d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/b6c8f347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/95893d2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/f5464aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Alexander # 210 - Queen Suite West End 9.4/10 Exceptional (3) "Great restaurant and bar on site. Staff are superb. The best place to stay on Cayman Brac!" £206 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/West-End-Hotels-The-Alexander-210-Queen-Suite.h49000374.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/065d18cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/178835fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/4e599586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/201ded24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Alexander Suites - #103 Queen Suite West End 8.8/10 Excellent (3) "All around great experience with this property. Interior layout of the hotel and grounds was beautiful and well kept. Rooms were upscale, clean and had small kitchenette - really appreciate how they had coffee makers and a fully stocked kitchen with small appliances including dishware, utensils, cups etc... Property was close to airport, ATM (only one on the island) and to town for quick supermarket runs. Couple of restaurants within walking distance and really close to several snorkeling sites... £202 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/West-End-Hotels-The-Alexander-107-Queen-Suite.h45473215.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/6a91b423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/0f62101e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/0767edcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/523f8ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Alexander Suites #102 - Double Queen West End 10/10 Exceptional (1) "This was the perfect place for our short Cayman Brac trip. Next time we will stay longer. Absolutely no negative comments…highly recommend😃" £252 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/West-End-Hotels-The-Alexander-Suites-102-Double-Queen.h45522008.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/7ccf8361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/a6e77d16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/f93dae03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/3d0e4f0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alexander - # 105 Queen Suite West End £202 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/West-End-Hotels-The-Alexander-105-Queen-Suite.h46108028.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/05e5b681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/1766a27b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/43b985a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/5ca749d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Alexander - #201 2 Bedroom Suite West End 10/10 Exceptional (2) "Excellent staff, restaurant was nice." £313 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/West-End-Hotels-The-Alexander-201-2-Bedroom-Suite.h46108602.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-04&endDate=2025-10-05®ionId=553248633946460050&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Sister Islands Hotel Reviews