Title: Second Mesa Travel Guide: Best of Second Mesa, Arizona Travel 2025 | Expedia.co.uk [Hotels in Second Mesa](https://expedia.co.uk/Second-Mesa-Hotels.d553248624339242280.Travel-Guide-Hotels)[Holiday Rentals in Second Mesa](https://expedia.co.uk/Second-Mesa-Holiday-Rentals.d553248624339242280.Travel-Guide-HolidayRentals)[Second Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Second-Mesa.d553248624339242280.Car-Hire-Guide)[Second Mesa Holidays](https://expedia.co.uk/Second-Mesa.d553248624339242280.Holidays-City-Breaks) # Second Mesa Travel Guide ## Tourist Guide ![Photo by Yasser Hamid Syed](https://mediaim.expedia.com/destination/2/197d2580a91a6b51818947d18e1a7a81.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Yasser Hamid Syed](https://mediaim.expedia.com/destination/2/197d2580a91a6b51818947d18e1a7a81.jpg) ## Visit Second Mesa - Top hotels in Second Mesa - Top Holiday Rentals in Second Mesa ![Hopi Cultural Center](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/3974928f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hopi Cultural Center Highway 264, Milepost 379, Second Mesa, AZ £95 13 Nov - 14 Nov includes taxes & fees Stay at this motel in Second Mesa. Enjoy free Wi-Fi, free parking and a conference centre. Our guests praise the helpful staff in their reviews. 8.2/10 Very Good! (342 reviews) It’s the only place to stay on the Hopi reservation and offers decent all around value. Reviewed on 29 Oct 2025 [](https://expedia.co.uk/Hotel-Search?startDate=13%2F11%2F2025&endDate=14%2F11%2F2025&selected=17067718&PinnedHotelID=17067718&HadPinnedHotel=true®ionId=553248624339242280) [See all properties in Second Mesa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=13%2F11%2F2025&endDate=14%2F11%2F2025®ionId=553248624339242280) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Scottsdale Camelback Resort](https://images.trvl-media.com/lodging/2000000/1190000/1184200/1184132/1a65e3f9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Scottsdale Camelback Resort 6302 E Camelback Rd, Scottsdale, AZ Stay at this 4-star spa condo in Scottsdale. Enjoy free parking, a full-service spa and breakfast (surcharge). Our guests praise the pool and the helpful staff ... 8.8/10 Excellent! (1,255 reviews) Villa was spacious and pool area was great Reviewed on 8 Nov 2025 [](https://expedia.co.uk/Phoenix-Hotels-Scottsdale-Camelback-Resort.h1184132.Hotel-Information) ![Sedona Pines Resort](https://images.trvl-media.com/lodging/10000000/9380000/9373900/9373888/0562ba9a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sedona Pines Resort 6701 W State Route 89A, Sedona, AZ Stay at this 3.5-star family-friendly condo in Sedona. Enjoy free Wi-Fi, free parking and room service. Our guests praise the pool and the restaurant in their ... 9.2/10 Wonderful! (1,777 reviews) The tiny house was really nice! It had everything we needed. The staff were very accomodating, and the on site restaurant was really good. We enjoyed our stay! Reviewed on 8 Nov 2025 [](https://expedia.co.uk/Sedona-Hotels-Sedona-Pines-Resort.h9373888.Hotel-Information) ![Sentral Old Town](https://images.trvl-media.com/lodging/82000000/81220000/81214700/81214699/190b0221_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sentral Old Town 4753 N. Scottsdale Rd., Scottsdale, AZ Stay at this 4-star aparthotel in Scottsdale. Enjoy a fitness centre, parking (surcharge) and a pool table. Our guests praise the helpful staff in their reviews. ... 8.4/10 Very Good! (484 reviews) Nice place. Not more than 4 star but everything was clean, decent sheets and mattress. Reviewed on 7 Nov 2025 [](https://expedia.co.uk/Phoenix-Hotels-Sentral-Old-Town.h81214699.Hotel-Information) [See all 35,229 properties in Arizona](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=204&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Second Mesa hotel availability [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-12&endDate=2025-11-13) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-12&endDate=2025-11-13) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-12&endDate=2025-11-13) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-12&endDate=2025-11-13)[12 Nov - 13 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-12&endDate=2025-11-13) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-13&endDate=2025-11-14) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-13&endDate=2025-11-14) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-13&endDate=2025-11-14) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-13&endDate=2025-11-14)[13 Nov - 14 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=2025-11-13&endDate=2025-11-14) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=14%2F11%2F2025&endDate=16%2F11%2F2025) [This weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=14%2F11%2F2025&endDate=16%2F11%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=14%2F11%2F2025&endDate=16%2F11%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=14%2F11%2F2025&endDate=16%2F11%2F2025)[14 Nov - 16 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=14%2F11%2F2025&endDate=16%2F11%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=21%2F11%2F2025&endDate=23%2F11%2F2025) [Next weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=21%2F11%2F2025&endDate=23%2F11%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=21%2F11%2F2025&endDate=23%2F11%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248624339242280&startDate=21%2F11%2F2025&endDate=23%2F11%2F2025)[21 Nov - 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[Visit St. Michaels](https://www.expedia.co.uk/St-Michaels.dx181393) - [Visit Teec Nos Pos](https://www.expedia.co.uk/Teec-Nos-Pos.dx6192878) - [Visit Tsaile](https://www.expedia.co.uk/Tsaile.dx3000424257) - [Visit Tuba City](https://www.expedia.co.uk/Tuba-City.dx55207) - [Visit Walpi](https://www.expedia.co.uk/Walpi.dx553248635974599797) - [Visit West Fork Oak Creek Trail](https://www.expedia.co.uk/West-Fork-Oak-Creek-Trail.dx553248621532645111) - [Winslow Holidays](https://www.expedia.co.uk/Winslow.d7907.Holidays-City-Breaks) - [Car hire Cameron](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cameron.d6179534.Car-Hire-Guide) - [Car hire near Northern Arizona](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Northern-Arizona.d6054760.Car-Hire-Guide) - [Dollar Rent A Car Rental Cars in Northern Arizona](https://www.expedia.co.uk/Dollar-Rent-A-Car-Car-Rentals-In-Northern-Arizona.d6054760-c43.Car-Rental-Guide-Suppliers) - [Northern Arizona Holiday Rentals](https://www.expedia.co.uk/Northern-Arizona-Holiday-Rentals.d6054760.Travel-Guide-HolidayRentals) - [Things to do in Northeast Arizona](https://www.expedia.co.uk/Things-To-Do-In-Northeast-Arizona.d6229504.Travel-Guide-Activities) - [Things to do in Northern Arizona](https://www.expedia.co.uk/Things-To-Do-In-Northern-Arizona.d6054760.Travel-Guide-Activities) - [Things to do in Tuba City](https://www.expedia.co.uk/Things-To-Do-In-Tuba-City.d55207.Travel-Guide-Activities) - Cities near Second Mesa - Places of interest [Kykotsmovi Village](https://expedia.co.uk/Kykotsmovi-Village.dx3000423775) - [Painted Desert](https://expedia.co.uk/Painted-Desert-Arizona.d553248635975357254.Attraction) - [Old Oraibi](https://expedia.co.uk/Old-Oraibi-Kykotsmovi-Village.d6085695.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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