Title: The Best Hotels Closest to Science Center of Iowa in Des Moines - 2026 Updated Prices | Expedia.co.uk [Science Center of Iowa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Science-Center-Of-Iowa.d6075028.Car-Hire-Guide)[Science Center of Iowa Holidays](https://expedia.co.uk/Science-Center-Of-Iowa-Downtown-Des-Moines.d6075028.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [7 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Feb - 9 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-02-08&endDate=2026-02-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Science Center of Iowa hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/a4499f56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/71578742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/31b1da89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/bb5c245f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Des Lux Hotel [](https://www.expedia.co.uk/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) Court District, 0.5 mi from Science Center of Iowa 9.8/10 Exceptional (1,035 reviews) "Great stay will do again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £125 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/37a0aa7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/e9d1d1c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/293ddc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fort Des Moines, Curio Collection by Hilton [](https://www.expedia.co.uk/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) Western Gateway, 0.5 mi from Science Center of Iowa 9.6/10 Exceptional (1,082 reviews) "Clean hotel from top to bottom, friendly staff, and great food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £111 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/091412b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/e56a1688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/5c0974c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/68a79c4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Surety Hotel, Autograph Collection [](https://www.expedia.co.uk/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) Court District, 0.3 mi from Science Center of Iowa 9.4/10 Exceptional (1,001 reviews) "Great Staff ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £160 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/f9defb4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/d1c0acc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/cd7a376b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Des Moines Downtown by IHG [](https://www.expedia.co.uk/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) Historic East Village, 0.5 mi from Science Center of Iowa 9.4/10 Exceptional (1,002 reviews) "Nice stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dave £80 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/53b90d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/b31ca2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7f9d044a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7621407d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Des Moines Downtown by IHG [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) Downtown Des Moines, 0.5 mi from Science Center of Iowa 9.2/10 Wonderful (987 reviews) "Great room, good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason £90 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/dcec07a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/2feb61a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/24dbb58e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/1225329f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel Des Moines East Village [](https://www.expedia.co.uk/Des-Moines-Hotels-AC-Hotel-Des-Moines-East-Village.h16525760.Hotel-Information) Historic East Village, 0.6 mi from Science Center of Iowa 9.2/10 Wonderful (407 reviews) "Great hotel in a great location in downtown Des Moines " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £124 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-AC-Hotel-Des-Moines-East-Village.h16525760.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/3d4c6021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/56241628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch flat-screen TV with premium TV channels, TV, pay films](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/a8a15c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/c9522ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Des Moines Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Hilton-Des-Moines-Downtown.h21321542.Hotel-Information) Downtown Des Moines, 0.6 mi from Science Center of Iowa 9.0/10 Wonderful (1,001 reviews) "Great location and parking accommodation." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt £125 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Des-Moines-Hotels-Hilton-Des-Moines-Downtown.h21321542.Hotel-Information) ![2 restaurants, breakfast, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/w4000h2662x0y0-b9dcf24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 5 AM to midnight, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/e7dcdb07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/56eb4ee4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/724f01ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Des Moines Marriott Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Des-Moines-Marriott-Downtown.h16933.Hotel-Information) Downtown Des Moines, 0.5 mi from Science Center of Iowa 8.8/10 Excellent (960 reviews) "Great location, clean, easy check in and check out. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily £126 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Des-Moines-Hotels-Des-Moines-Marriott-Downtown.h16933.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/63d184cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/535602f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/1137cad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/537ac8be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Des Moines Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Fairfield-Inn-Suites-By-Marriott-Des-Moines-Downtown.h36938080.Hotel-Information) Downtown Des Moines, 0.8 mi from Science Center of Iowa 9.0/10 Wonderful (403 reviews) "Clean, quiet, affordable,and an excellent breakfast! Right across the street from the casey center." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £79 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Fairfield-Inn-Suites-By-Marriott-Des-Moines-Downtown.h36938080.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/f0edf04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/0e9a7aad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/c095d752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/bd5c2167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Des Moines Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Hampton-Inn-Suites-Des-Moines-Downtown.h7897548.Hotel-Information) Court District, 0.1 mi from Science Center of Iowa 8.6/10 Excellent (1,007 reviews) "The room was clean and comfortable. The location was wonderful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy £80 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Hampton-Inn-Suites-Des-Moines-Downtown.h7897548.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/69eea272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/12ec6fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/0898edfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/c0c4d0dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Des Moines Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Residence-Inn-Des-Moines-Downtown.h6468142.Hotel-Information) Court District, 0.1 mi from Science Center of Iowa 8.6/10 Excellent (581 reviews) "The room was spotless and the staff at check in were some of the friendliest we have met! We would give it 10 stars if we could! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £79 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Residence-Inn-Des-Moines-Downtown.h6468142.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/2189a8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/bbd73c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/ccf37cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/2f355e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Event Center [](https://www.expedia.co.uk/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) Downtown Des Moines, 0.8 mi from Science Center of Iowa 8.8/10 Excellent (1,001 reviews) "Nice clean rooms with great parking and good breakfast. Easily located downtown " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glen A. £82 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/3c6db2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Double Beds | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/f27c17ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/f5fc26df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/801e742f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Des Moines Savery Hotel [](https://www.expedia.co.uk/Des-Moines-Hotels-Renaissance-Des-Moines-Savery-Hotel.h10733.Hotel-Information) Downtown Des Moines, 0.3 mi from Science Center of Iowa 8.6/10 Excellent (1,001 reviews) "Clean and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jodi £119 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Renaissance-Des-Moines-Savery-Hotel.h10733.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/baae5559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/4530bad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/d5bc4613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/64040fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Hotel Des Moines Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) Historic East Village, 0.4 mi from Science Center of Iowa 8.2/10 Very good (1,018 reviews) "Great atmosphere and quiet rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MICHAEL £107 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/0f5c3279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/d3c7f8ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/aed2404a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/719fc843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Des Moines/Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) Downtown Des Moines, 0.4 mi from Science Center of Iowa 8.2/10 Very good (1,001 reviews) "Room was great, location is great, and the breakfast was fantastic! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £77 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/56a1214f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/784152cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/f2ae5ea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/4aec793b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Downtown - Mercy Area by IHG [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Downtown-Mercy-Area.h18835.Hotel-Information) Downtown Des Moines, 1 mi from Science Center of Iowa 8.0/10 Very good (1,000 reviews) "Clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £92 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Downtown-Mercy-Area.h18835.Hotel-Information) ![Standard Double Room | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/be13159b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Bathroom | Shower, hair dryer, towels](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/eec7fca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/2cb93733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/13ca4d38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Rest Motel [](https://www.expedia.co.uk/Des-Moines-Hotels-Cozy-Rest-Motel.h9776190.Hotel-Information) Indianola Hills, 1.7 mi from Science Center of Iowa 7.8/10 Good (652 reviews) "This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck £58 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Cozy-Rest-Motel.h9776190.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/4605db88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/a33da0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/ea6bade1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Des Moines at Drake University [](https://www.expedia.co.uk/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) Drake, 2.1 mi from Science Center of Iowa 9.4/10 Exceptional (1,011 reviews) "Room and hotel was very clean, staff were friendly, would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron £74 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/fcd8bd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/f005535b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed | Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/4622c857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/244284f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Des Moines Airport [](https://www.expedia.co.uk/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) 3.3 mi from Science Center of Iowa 8.6/10 Excellent (1,744 reviews) "good value and a very good breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARK £54 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/9e02de50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Study with Chaise) | Premium bedding, pillow-top beds, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/05d77222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/28a78bd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/d046e68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Des Moines-Airport [](https://www.expedia.co.uk/Des-Moines-Hotels-Hampton-Inn-Des-Moines-Airport.h17394.Hotel-Information) 3.3 mi from Science Center of Iowa 8.8/10 Excellent (1,003 reviews) "Great room/breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leonard £87 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Des-Moines-Hotels-Hampton-Inn-Des-Moines-Airport.h17394.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22®ionId=6075028&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Science Center of Iowa | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/8b738b8d.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Des Lux Hotel | 3.5 star property | 9.8Exceptional1,035 reviews | View | | | | | | | ![Dinner served](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Fort Des Moines, Curio Collection by Hilton | 4.5 star property | 9.6Exceptional1,082 reviews | View | | | | | | | ![Restaurant](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/091412b2.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Surety Hotel, Autograph Collection | 4.0 star property | 9.4Exceptional1,001 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Staybridge Suites Des Moines Downtown by IHG | 3.0 star property | 9.4Exceptional1,002 reviews | View | | | | | | | ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/53b90d46.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Des Moines Downtown by IHG | 2.5 star property | 9.2Wonderful987 reviews | View | | | | | | ## Top Science Center of Iowa Hotel Reviews ![Des Lux Hotel](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30_y.jpg) ### Des Lux Hotel 10/10 Excellent "The front desk lady was very nice and helpful! This was one of my favorite places to stay. So thank you all. " [](https://expedia.co.uk/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Home2 Suites by Hilton Des Moines at Drake University](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e_y.jpg) ### Home2 Suites by Hilton Des Moines at Drake University 10/10 Excellent "Clean, spacious, great amenities, and the sheets were super soft." [](https://expedia.co.uk/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Staybridge Suites Des Moines Downtown by IHG](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514_y.jpg) ### Staybridge Suites Des Moines Downtown by IHG 10/10 Excellent "The staff was beyond lovely, the room was so tidy and clean when I got in. Nicest hotel stay I’ve had in a very long time - thank you so much!" [](https://expedia.co.uk/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) ![Des Moines Marriott Downtown](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/5f870b3a_y.jpg) ### Des Moines Marriott Downtown 10/10 Excellent "GREAT PLACE TO STAY" [](https://expedia.co.uk/Des-Moines-Hotels-Des-Moines-Marriott-Downtown.h16933.Hotel-Information) ![Hampton Inn & Suites Des Moines Downtown](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/c095d752_y.jpg) ### Hampton Inn & Suites Des Moines Downtown 10/10 Excellent "Courteous helpful staff, location close to many places and events" [](https://expedia.co.uk/Des-Moines-Hotels-Hampton-Inn-Suites-Des-Moines-Downtown.h7897548.Hotel-Information) ![Surety Hotel, Autograph Collection](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/5c0974c4_y.jpg) ### Surety Hotel, Autograph Collection 10/10 Excellent "Beautiful, clean rooms. Excellent customer service." [](https://expedia.co.uk/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) ![Hyatt Place Des Moines/Downtown](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/c5d9ac95_y.jpg) ### Hyatt Place Des Moines/Downtown 10/10 Excellent "It was excellent. Easy, friendly and efficient " [](https://expedia.co.uk/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) ![Renaissance Des Moines Savery Hotel](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/317644dd_y.jpg) ### Renaissance Des Moines Savery Hotel 10/10 Excellent "The night staff was extremely helpful! They made my stay worthwhile. Because of them I will definitely be returning." [](https://expedia.co.uk/Des-Moines-Hotels-Renaissance-Des-Moines-Savery-Hotel.h10733.Hotel-Information) ![Near Wells Fargo, King Bed and Balcony and washer dryer, fitness room, Fireplace](https://images.trvl-media.com/lodging/107000000/106390000/106389900/106389832/484561f9_y.jpg) ### Near Wells Fargo, King Bed and Balcony and washer dryer, fitness room, Fireplace 10/10 Excellent "My partner and I stayed with our dogs at this adorable apartment. The apartment was cute, cozy and had comfortable furniture. The location was ideal for meeting up with our family and friends and loved the walk-abilty to restaurants and Hy-Vee/Starbucks. Our host was very responsive and helpful. The only downfall of the property would be that on Thanksgiving day the Turkey Trot placed a speaker right next to the building and it was loud. So no fault of the property!" [](https://expedia.co.uk/Des-Moines-Hotels-Near-Wells-Fargo.h106389832.Hotel-Information) ## Hotels near other Science Center of Iowa attractions ### Principal Park 4.5/5 (64 reviews) Catch an event at Principal Park during your trip to Des Moines. Experience the area's great live music and lively festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6075046) ### Des Moines' Downtown Farmers' Market You can search for that perfect souvenir at Des Moines' Downtown Farmers' Market during your stay in Des Moines. Experience the area's great live music and acclaimed theatre scene. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=884736698079137792) ### Polk County Courthouse After visiting Polk County Courthouse, make a plan to see the other sights and activities in Des Moines. Experience the great live music and lively festivals in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561929896) ### Des Moines Civic Center 4.3/5 (220 reviews) Des Moines Civic Center is just one of the places to see in Des Moines, so why not enjoy the other things to explore during your travels? Experience the area's great live music and acclaimed theatre scene. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6170662) ### Walnut Street Bridge You can learn about the history of Des Moines with a visit to Walnut Street Bridge. Experience the area's great live music and lively festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6075050) ### World Food Prize Hall of Laureates You can spend an afternoon exploring the galleries in World Food Prize Hall of Laureates during your trip to Des Moines. Experience the lively festivals and great live music in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561929895) ### Simon Estes Riverfront Amphitheater You can get tickets for a performance at Simon Estes Riverfront Amphitheater during your stay in Des Moines. Experience the area's acclaimed theatre scene or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6170659) ### Ruan Center Learn about the local history of Des Moines when you take a trip to Ruan Center. Experience the area's lively festivals or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6210743) ## Frequently asked questions ### What's the area like around Science Center of Iowa? ### What's the best place to stay close to Science Center of Iowa? ### How many hotels can I expect to find near Science Center of Iowa? ### If I need to cancel the hotel reservation for my stay near Science Center of Iowa, will I receive a refund? ### What can I see and do near Science Center of Iowa?