Title: The Best Hotels Closest to Science Center of Iowa in Des Moines - 2026 Updated Prices | Expedia.co.uk [Science Center of Iowa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Science-Center-Of-Iowa.d6075028.Car-Hire-Guide)[Science Center of Iowa Holidays](https://expedia.co.uk/Science-Center-Of-Iowa-Downtown-Des-Moines.d6075028.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [27 Mar - 28 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-03-27&endDate=2026-03-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-03-28&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6075028&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Science Center of Iowa hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/a4499f56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/71578742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/bb5c245f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/31b1da89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Des Lux Hotel [](https://www.expedia.co.uk/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) Court District, 0.5 mi from Science Center of Iowa 9.8/10 Exceptional (1,049 reviews) "Love this hotel every time we stay, never disappoints. Great staff, rooms, spa, breakfast, location and overall value." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori £128 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/bee30b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/e9d1d1c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/293ddc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fort Des Moines, Curio Collection by Hilton [](https://www.expedia.co.uk/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) Western Gateway, 0.5 mi from Science Center of Iowa 9.6/10 Exceptional (1,099 reviews) "Loved our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lexanne £123 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/091412b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/e56a1688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/68a79c4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/34d6d27a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Surety Hotel, Autograph Collection [](https://www.expedia.co.uk/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) Court District, 0.3 mi from Science Center of Iowa 9.4/10 Exceptional (1,000 reviews) "Nice staff and very nice room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonna £142 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/4f60096d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/d1c0acc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/f9defb4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Des Moines Downtown by IHG [](https://www.expedia.co.uk/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) Historic East Village, 0.5 mi from Science Center of Iowa 9.2/10 Wonderful (1,002 reviews) "Thoroughly enjoyed staying here!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Travantae £88 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/53b90d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7621407d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/5991d039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7f9d044a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Des Moines Downtown by IHG [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) Downtown Des Moines, 0.5 mi from Science Center of Iowa 9.2/10 Wonderful (1,000 reviews) "We appreciated the shuttle to and from restaurants/bars. Very friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tara £78 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/dcec07a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/24dbb58e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/2feb61a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/e3727c53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel Des Moines East Village [](https://www.expedia.co.uk/Des-Moines-Hotels-AC-Hotel-Des-Moines-East-Village.h16525760.Hotel-Information) Historic East Village, 0.6 mi from Science Center of Iowa 9.2/10 Wonderful (412 reviews) "Very clea great location" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Paul £127 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-AC-Hotel-Des-Moines-East-Village.h16525760.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/3d4c6021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/c9522ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/56241628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/b236a38e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Des Moines Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Hilton-Des-Moines-Downtown.h21321542.Hotel-Information) Downtown Des Moines, 0.6 mi from Science Center of Iowa 9.0/10 Wonderful (1,001 reviews) "A front receptionist was repeatedly rude to the customers she managed over the phone. She was argumentative and denigrated her customers on the phone….including me. She argued with how I made my reservation - a phone call to Hilton reservations- she stated was made through a third party. That sort of rudeness required a re-think of her people-facing role. She became frustrated, her voices was raised, argumentative and simply rude. Never should she have access to customers. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason £127 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Hilton-Des-Moines-Downtown.h21321542.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/3c6db2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/801e742f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/f5fc26df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Double Beds | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/f27c17ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Des Moines Savery Hotel [](https://www.expedia.co.uk/Des-Moines-Hotels-Renaissance-Des-Moines-Savery-Hotel.h10733.Hotel-Information) Downtown Des Moines, 0.3 mi from Science Center of Iowa 8.6/10 Excellent (1,000 reviews) "Clean room, pleasant staff, & pretty quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie £116 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Renaissance-Des-Moines-Savery-Hotel.h10733.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/2189a8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/ccf37cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/949421a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/2f355e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Event Center [](https://www.expedia.co.uk/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) Downtown Des Moines, 0.8 mi from Science Center of Iowa 8.8/10 Excellent (1,000 reviews) "This place was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina £85 includes taxes & fees 18 Apr - 19 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/baae5559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/4530bad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/64040fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/66a408c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Hotel Des Moines Downtown [](https://www.expedia.co.uk/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) Historic East Village, 0.4 mi from Science Center of Iowa 8.2/10 Very good (1,002 reviews) "Everything was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacklyn J £103 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/56a1214f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/4aec793b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/58211348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/784152cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Downtown - Mercy Area by IHG [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Downtown-Mercy-Area.h18835.Hotel-Information) Downtown Des Moines, 1 mi from Science Center of Iowa 7.8/10 Good (1,003 reviews) "Clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donnie £111 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Downtown-Mercy-Area.h18835.Hotel-Information) ![Standard Double Room | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/be13159b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/13ca4d38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Bathroom | Shower, hair dryer, towels](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/eec7fca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/2cb93733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Rest Motel [](https://www.expedia.co.uk/Des-Moines-Hotels-Cozy-Rest-Motel.h9776190.Hotel-Information) Indianola Hills, 1.7 mi from Science Center of Iowa 7.8/10 Good (653 reviews) "The room was clean and the staff friendly. It is an old motel but was perfect for a quick stay while on the road as it is inexpensive. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ann £56 includes taxes & fees 1 Apr - 2 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Cozy-Rest-Motel.h9776190.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, free cots/infant beds](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/5d40e40e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/a33da0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/ea6bade1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Des Moines at Drake University [](https://www.expedia.co.uk/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) Drake, 2.1 mi from Science Center of Iowa 9.4/10 Exceptional (1,002 reviews) "Breakfast was amazing and staff were very welcome and friendly! Hope to stay here more often in the future!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adrian £89 includes taxes & fees 21 Apr - 22 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22100/22048/2d4e2e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22048/df4328f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/30000/22100/22048/8710d9a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/22100/22048/1f78435f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Des Moines [](https://www.expedia.co.uk/Des-Moines-Hotels-Red-Roof-Inn-Des-Moines.h22048.Hotel-Information) 4.8 mi from Science Center of Iowa 6.8/10 (554 reviews) "Room was clean. All dispensers were full. Had kleenex. King bed was clean and comfortable. TV was decent size. Very nice change from inns we stayed at down south!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rose £47 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Des-Moines-Hotels-Red-Roof-Inn-Des-Moines.h22048.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/9e02de50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/7983d49f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/28a78bd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Study with Chaise) | Premium bedding, pillow-top beds, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/05d77222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Des Moines-Airport [](https://www.expedia.co.uk/Des-Moines-Hotels-Hampton-Inn-Des-Moines-Airport.h17394.Hotel-Information) Watrous South, 3.3 mi from Science Center of Iowa 8.8/10 Excellent (1,000 reviews) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marc £106 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Hampton-Inn-Des-Moines-Airport.h17394.Hotel-Information) ![Desk, soundproofing, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/fcd8bd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/f005535b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed | Desk, soundproofing, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/4622c857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/244284f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Des Moines Airport [](https://www.expedia.co.uk/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) Watrous South, 3.3 mi from Science Center of Iowa 8.6/10 Excellent (1,748 reviews) "Super close to airport and very comfortable!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy £58 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717367/13368e67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717367/c82b7913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717367/811de261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717367/f8108d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Ankeny Des Moines [](https://www.expedia.co.uk/Des-Moines-Hotels-WoodSpring-Suites-Ankeny.h1717367.Hotel-Information) 6.8 mi from Science Center of Iowa 6.6/10 (251 reviews) "The staff was very polite and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £42 includes taxes & fees 1 Apr - 2 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-WoodSpring-Suites-Ankeny.h1717367.Hotel-Information) ![Studio, 2 Double Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/160000/151200/151170/08426e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/151200/151170/eb99c004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed, Accessible, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/160000/151200/151170/ec652f62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/160000/151200/151170/e516da37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Select Suites - Des Moines - Urbandale [](https://www.expedia.co.uk/Des-Moines-Hotels-Extended-Stay-America-Suites-Des-Moines-Urbandale.h151170.Hotel-Information) 8.7 mi from Science Center of Iowa 6.8/10 (913 reviews) "Great room. Front desk staff were amazing -- Very friendly. Nice sized, clean rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joshua £53 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Des-Moines-Hotels-Extended-Stay-America-Suites-Des-Moines-Urbandale.h151170.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2160000/2154400/2154341/597ef6d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2160000/2154400/2154341/abaaf7d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2160000/2154400/2154341/46b41a3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/3000000/2160000/2154400/2154341/c38e8a12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Des Moines Airport [](https://www.expedia.co.uk/Des-Moines-Hotels-Fairfield-Inn-Suites-By-Marriott-Des-Moines-Airport.h2154341.Hotel-Information) 4.4 mi from Science Center of Iowa 9.2/10 Wonderful (639 reviews) "Very clean, convenient, excellent staff, Airport Shuttle on time. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ruth A £103 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Fairfield-Inn-Suites-By-Marriott-Des-Moines-Airport.h2154341.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/5e6768d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/2ed290e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/23e5f990.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/c78cf585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Des Moines, IA - North [](https://www.expedia.co.uk/Des-Moines-Hotels-Motel-6-Des-Moines.h1037758.Hotel-Information) 4.8 mi from Science Center of Iowa 5.8/10 (294 reviews) "Very nice staff, plain Jane room, the place was run down but it was clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy £44 includes taxes & fees 9 Apr - 10 Apr [](https://www.expedia.co.uk/Des-Moines-Hotels-Motel-6-Des-Moines.h1037758.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-10&endDate=2026-04-11®ionId=6075028&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Science Center of Iowa | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/a4499f56.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Des Lux Hotel | 3.5 star property | 9.8Exceptional1,049 reviews | View | | | | | | | ![Dinner served](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Fort Des Moines, Curio Collection by Hilton | 4.5 star property | 9.6Exceptional1,099 reviews | View | | | | | | | ![Restaurant](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/091412b2.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Surety Hotel, Autograph Collection | 4.0 star property | 9.4Exceptional1,000 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Staybridge Suites Des Moines Downtown by IHG | 3.0 star property | 9.2Wonderful1,002 reviews | View | | | | | | | ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/53b90d46.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Des Moines Downtown by IHG | 2.5 star property | 9.2Wonderful1,000 reviews | View | | | | | | ## Top Science Center of Iowa Hotel Reviews ![Des Moines Marriott Downtown](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/w4000h2662x0y0-b9dcf24b_y.jpg) ### Des Moines Marriott Downtown 10/10 Excellent "I traveled for work and the staff was friendly from beginning to end. Each person, from valet to front desk were pleasant to work with. The rooms were not carpeted, and instead had linoleum wood flooring, which I was fine with and honestly preferred. Bathrooms were clean, and the area was easy to walk to and from the events center. I'd stay here again. " [](https://expedia.co.uk/Des-Moines-Hotels-Des-Moines-Marriott-Downtown.h16933.Hotel-Information) ![Hotel Fort Des Moines, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b_y.jpg) ### Hotel Fort Des Moines, Curio Collection by Hilton 10/10 Excellent "Clean room, very stylish bathroom with lavender scented toiletries. I wish the facility had more moisture in the air because the ultra dry air gave me a low grade migraine but was very beautiful. I was there as a wedding guest. They offer very unique and preferred option for the guests like a social hour with orderves before being seated for the dinner followed the wedding. " [](https://expedia.co.uk/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) ![Holiday Inn Downtown - Mercy Area by IHG](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/56a1214f_y.jpg) ### Holiday Inn Downtown - Mercy Area by IHG 4/10 Poor "Distant parking lot due to “structural issues” of ramp. A/C was poor. Staff were friendly enough and accommodating " [](https://expedia.co.uk/Des-Moines-Hotels-Holiday-Inn-Downtown-Mercy-Area.h18835.Hotel-Information) ![Hilton Des Moines Downtown](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/3d4c6021_y.jpg) ### Hilton Des Moines Downtown 10/10 Excellent "A front receptionist was repeatedly rude to the customers she managed over the phone. She was argumentative and denigrated her customers on the phone….including me. She argued with how I made my reservation - a phone call to Hilton reservations- she stated was made through a third party. That sort of rudeness required a re-think of her people-facing role. She became frustrated, her voices was raised, argumentative and simply rude. Never should she have access to customers. " [](https://expedia.co.uk/Des-Moines-Hotels-Hilton-Des-Moines-Downtown.h21321542.Hotel-Information) ![Hyatt Place Des Moines/Downtown](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/0f5c3279_y.jpg) ### Hyatt Place Des Moines/Downtown 4/10 Poor "Please let me begin that I have been a Hyatt Rewards member for over two decades. Hyatt Hotels were a go-to”during my business and conference travels. Further, I have stayed at this property a number of times since its opening. I was amazed at the amount of wear and tear at this property. Wood trim on every surface was noticeably scratched, chipped or damaged in some way, the sofa fabric had a tear, etc., making it hard to determine if the facility was clean or not as the air of dinginess was everywhere. I found it hard to believe that the Hyatt brand would allow this type of surfaces that diminished the feel of the property. Otherwise, all seemed orderly, staff were pleasant, everything was operational, breakfast was tasty…but the spaces I accessed had seen far more better days in the past. " [](https://expedia.co.uk/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) ![Residence Inn Des Moines Downtown](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/69eea272_y.jpg) ### Residence Inn Des Moines Downtown 10/10 Excellent "The rooms were very nice and it was great to have a hot breakfast every morning." [](https://expedia.co.uk/Des-Moines-Hotels-Residence-Inn-Des-Moines-Downtown.h6468142.Hotel-Information) ![Fairfield Inn & Suites by Marriott Des Moines Downtown](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/63d184cc_y.jpg) ### Fairfield Inn & Suites by Marriott Des Moines Downtown 10/10 Excellent "Beautiful place. One of the most spacious places we've ever been My kids were so happy about how spacious the suite was. Staff members were very friendly " [](https://expedia.co.uk/Des-Moines-Hotels-Fairfield-Inn-Suites-By-Marriott-Des-Moines-Downtown.h36938080.Hotel-Information) ![Staybridge Suites Des Moines Downtown by IHG](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514_y.jpg) ### Staybridge Suites Des Moines Downtown by IHG 6/10 Okay "It was close to the hospital/costs too much to park for what you have to pay for the room/staff was a tad rude " [](https://expedia.co.uk/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) ![Comfort Inn & Suites Event Center](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/2189a8cc_y.jpg) ### Comfort Inn & Suites Event Center 10/10 Excellent "Our room was clean, breakfast was great and the staff was pleasant and accommodating. We had a great stay!" [](https://expedia.co.uk/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) ## Hotels near other Science Center of Iowa attractions ### Principal Park 4.5/5 (64 reviews) Catch an event at Principal Park during your trip to Des Moines. Experience the area's acclaimed theatre scene and great live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6075046) ### Des Moines' Downtown Farmers' Market You can search for that perfect souvenir at Des Moines' Downtown Farmers' Market during your stay in Des Moines. Experience the area's acclaimed theatre scene and great live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=884736698079137792) ### Polk County Courthouse After visiting Polk County Courthouse, make a plan to see the other sights and activities in Des Moines. Experience the great live music and lively festivals in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561929896) ### Des Moines Civic Center 4.3/5 (220 reviews) Enjoy an outing to Des Moines Civic Center during your stay in Des Moines. Experience the area's acclaimed theatre scene and lively festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6170662) ### Walnut Street Bridge You can learn about the history of Des Moines with a visit to Walnut Street Bridge. Experience the area's acclaimed theatre scene and great live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6075050) ### World Food Prize Hall of Laureates You can spend an afternoon exploring the galleries in World Food Prize Hall of Laureates during your trip to Des Moines. Experience the great live music and lively festivals in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561929895) ### Simon Estes Riverfront Amphitheater You can get tickets for a performance at Simon Estes Riverfront Amphitheater during your stay in Des Moines. Experience the area's great live music or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6170659) ### Ruan Center Learn about the local history of Des Moines when you take a trip to Ruan Center. Experience the area's lively festivals or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6210743) ## Frequently asked questions ### What's the area like around Science Center of Iowa? ### What's the best place to stay close to Science Center of Iowa? ### How many hotels can I expect to find near Science Center of Iowa? ### If I need to cancel the hotel reservation for my stay near Science Center of Iowa, will I receive a refund? ### What can I see and do near Science Center of Iowa?