São Francisco Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your São Francisco Holiday

Take all the hassle out of planning your next getaway with a São Francisco holiday package. Soak in the sounds and sights of this enticing neighbourhood and experience what it has to offer. Start your trip to São Francisco by heading to nearby attractions such as Teatro Amazonas, Amazon Arena and Mindu Municipal Park. Stop dreaming and start doing. When you're ready to lock in your next holiday to São Francisco, Expedia will help get you there.

Where to stay in São Francisco

Find the best São Francisco areas and neighborhoods for the activities you enjoy most. Learn more about São Francisco
A coastal cityscape with a prominent pink and yellow domed building, a clear blue sea, and a distant bridge.

Manaus Centro

2 out of top 10 points of interest in this area
3/5(3 area reviews)

Manaus Centro is noteworthy for its theatres, and you can make a stop at top attractions like Teatro Amazonas and Port of Manaus.

Find hotels in Manaus Centro

Top hotels in São Francisco

Hotel Express Vieiralves

Hotel Express Vieiralves

3 out of 5
Rua Rio Branco, s/n Manaus AM
Fully refundableReserve now, pay when you stay
The price is £27 per night from 5 Jul to 6 Jul
£27
5 Jul - 6 Jul
includes taxes & fees
8.4/10 Very good! (1,009 reviews)
"Internet is horrible"

Reviewed on 22 Jun 2026

Hotel Express Vieiralves
Rede Andrade Amazônia

Rede Andrade Amazônia

3 out of 5
Av. Getúlio Vargas 227 Manaus AM
Fully refundableReserve now, pay when you stay
The price is £24 per night from 27 Jul to 28 Jul
£24
27 Jul - 28 Jul
includes taxes & fees
8/10 Very good! (1,007 reviews)
"This hotel is nice and worth with the cheap money I spent. I recommend this hotel."

Reviewed on 28 Jun 2026

Rede Andrade Amazônia
Quality Hotel Manaus

Quality Hotel Manaus

3.5 out of 5
Avenida Mario Ypiranga, 1090 Manaus Amazonas
Fully refundableReserve now, pay when you stay
The price is £91 per night from 3 Jul to 4 Jul
£91
3 Jul - 4 Jul
includes taxes & fees
8.4/10 Very good! (523 reviews)
"We are in Manaus at least yearly. The Choice Hotel Manaus was a pleasant stay and we will probably stay again. Three minutes walk to the Manauara Mall is a strong draw and they charge for it. Compared to other Manaus stays, the Choice Hotel stands out for cleanliness, room maintenance, responsiveness ..."

Reviewed on 23 Jun 2026

Quality Hotel Manaus
See all 232 properties in São Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a São Francisco travel package cost?
Starting from just , a travel package is your passport to low-cost travel. Build your own São Francisco getaway by selecting from our huge range of hotels, flights and rental cars.
If I'm not able to travel, can I cancel my São Francisco travel package?
If your holiday plans in São Francisco have changed, it's a relief to know that you can cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking was made more than 24 hours ago, your hotel, airline or car rental company may charge a cancellation fee. To learn more, check our Customer Service Portal.
How do I get a cheap travel package to São Francisco?
Combine your hotels and flights, toss in extras such as tours, and save with a São Francisco travel package. You won't just pick up awesome discounts on your escape — you'll have loads of choice within your reach too. When you book through Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels around the globe. Your unforgettable holiday begins right here, right now!
Does Expedia offer Book Now, Pay Later São Francisco holidays?
Your bank balance shouldn't prevent you from escaping on holiday, so Expedia has worked out a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book an incredible getaway without hurting your hip pocket. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your break. Consider one of these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in convenient monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your holiday in multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan with Klarna.

Where should I stay in São Francisco?
Urban explorers come from all over to see Mindu Municipal Park and Teatro Amazonas in São Francisco. Book a room near these fantastic attractions and visit them at your leisure.
What are the top hotels in São Francisco?
Go Inn Manaus and ibis Manaus Aeroporto are a couple of the most sought-after hotels in São Francisco. Why not look up the facilities and rates at each and then make a decision?
How far in advance should I book my São Francisco holiday?
Browse Expedia to compare international fares as soon as you've got your travel dates. You can usually purchase a ticket up to a year in advance. If you don't see your preferred carrier, or you're booking late, fear not. Cheap tickets to São Francisco sometimes emerge within weeks of departure.
What does an Expedia São Francisco travel package include?
From flights and hotels to car rentals, Expedia can help you create a São Francisco package that works for you. Holidaying for a week or two? Look into a hotel, flight and rental car bundle. If you can only manage a quick getaway, a hotel and airfare deal could suit you better. Tours and activities can be added once you've made your booking. Our travel packages make it simple to plan and save.
What should I know before booking a São Francisco travel package?
A package can be easier on the hip pocket than separately booking everything you need for your escape. For example, bundle your hotels, flights and rental cars and save a pretty penny. Whatever your holiday plans, there's sure to be a package that's right for you.
Can I choose my airline with a São Francisco Expedia travel package?
You certainly can. Expedia has access to more than 550 partner airlines all over the world, so choose the carrier that best suits your budget needs.

Things to do

Maroaga Cave

Presidente Figueiredo Tour

£71
per adult
Presidente Figueiredo Tour
A Whole Day in the Jungle

A Whole Day in the Jungle

£171
per adult
98% of travellers recommend
A Whole Day in the Jungle
Manaus to Belem 5-Day Local Boat Trip

Manaus to Belem 5-Day Local Boat Trip

£111
per adult
Manaus to Belem 5-Day Local Boat Trip
See all activities in Manaus

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.