São Francisco Holidays from £822

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Your São Francisco Holiday

Take all the hassle out of planning your next getaway with a São Francisco holiday package. Soak in the sounds and sights of this enticing neighbourhood and experience what it has to offer. Start your trip to São Francisco by heading to nearby attractions such as Teatro Amazonas, Amazon Arena and Mindu Municipal Park. Stop dreaming and start doing. When you're ready to lock in your next holiday to São Francisco, Expedia will help get you there.

Price found within the past 48 hours. Click for updated prices.
Hotel do Largo

Hotel do Largo

Manaus Centro
£822
per person
6 Nov - 13 Nov
found 1 day ago
Return direct flight included
Lisbon (LIS) to Manaus (MAO)
7.8/10 Good! (289 reviews)
Cheap, very central, breakfast ok, AC not great in my room, smells of moth balls (there were two little piles of them in my room--I guess to deter certain bugs--no cockroaches seen).

Reviewed on 7 Aug 2026

Anaconda Amazon Resort

Anaconda Amazon Resort

£1,158
per person
6 Nov - 13 Nov
found 1 day ago
Return direct flight included
Lisbon (LIS) to Manaus (MAO)
10/10 Exceptional! (1 review)
Mural Living Hotel Manaus

Mural Living Hotel Manaus

Manaus Centro
£833
per person
6 Nov - 13 Nov
found 1 day ago
Return direct flight included
Lisbon (LIS) to Manaus (MAO)
8.6/10 Excellent! (141 reviews)
Helpful staff. Bathroom could be better due to paint condition. Area nearby is a bit rough but ths hotel is quiet and safe.

Reviewed on 9 Jul 2026

Flat confortável no Tropical Executive

Flat confortável no Tropical Executive

Ponta Negra
£1,124
per person
6 Nov - 13 Nov
found 1 day ago
Return direct flight included
Lisbon (LIS) to Manaus (MAO)
6.6/10 (7 reviews)
Hotel casa dos Frades

Hotel casa dos Frades

Manaus Centro
£877
per person
6 Nov - 13 Nov
found 1 day ago
Return direct flight included
Lisbon (LIS) to Manaus (MAO)
8.4/10 Very good! (304 reviews)
Localização fantástica e ambientes lindos para fotos. O hotel preserva com charme sua identidade histórica de antiga residência de frades. Os funcionários da recepção, limpeza e cozinha são extremamente atenciosos e cordiais. Nosso quarto era excelente, muito confortável, com ótima cama, ar-condicionado, banheiro impecável, TV e frigobar. O terraço oferece uma vista privilegiada do Teatro Amazonas, do Largo de São Sebastião e da igreja ao lado. Fica perto de tudo: bares, restaurantes, cafeterias e lojas de artesanato a poucos metros de caminhada. O café da manhã é delicioso, com pratos típicos da culinária manauara preparados com muito esmero. Após 12 dias de estadia, o custo-benefício foi excelente. Recomendamos muito!

Reviewed on 23 Sept 2026

Where to stay in São Francisco

Find the best São Francisco areas and neighborhoods for the activities you enjoy most. Learn more about São Francisco
A coastal cityscape with a prominent pink and yellow domed building, a clear blue sea, and a distant bridge.

Manaus Centro

2 out of top 10 points of interest in this area

Manaus Centro is noteworthy for its theatres, and you can make a stop at top attractions like Teatro Amazonas and Palacio Rio Negro.

A dense tropical forest with large green leaves and red flowers.

Adrianopolis

1 out of top 10 points of interest in this area

Visitors to Adrianopolis enjoy its shopping, and if you want to do some exploring, Manauara Shopping is worth a stop.

A beach with a sandy shore, a water body, and a bridge in the distance.

Ponta Negra

1 out of top 10 points of interest in this area

Visitors to Ponta Negra enjoy its river views, and if you want to do some exploring, Ponta Negra Beach is worth a stop.

Default Image

Industrial District

1 out of top 10 points of interest in this area

Industrial District is noteworthy for its restaurants, and you can make a stop at top attractions like Studio 5 Festival Mall Manaus and Convention Center and Povos da Amazonia Cultural Center.

A classical building with columns and a dome, named 'EQUILARO C. RIBEIRO'.

Cidade Nova Manaus

While Cidade Nova Manaus isn't home to many top sights, Amazon Arena and Archipelago of Anavilhanas are some notable places to visit nearby.

Top hotels in São Francisco

Hotel Express Vieiralves

Hotel Express Vieiralves

Rua Rio Branco, s/n Manaus AM
£31
4 Oct - 5 Oct
includes taxes & fees
8.4/10 Very good! (1,007 reviews)
"Nice breakfast and restaurant"

Reviewed on 24 Sept 2026

Hotel Express Vieiralves
Hotel Intercity Manaus

Hotel Intercity Manaus

Rua Professor Marciano Armond, 544 Manaus AM
£62
2 Oct - 3 Oct
includes taxes & fees
8.6/10 Excellent! (1,005 reviews)
"Probably one of the best options for staying in the city proper. Hotel restaurant was fair to good but not excellent. Several outstanding restaurants within walking distance or a short taxi/uber ride. Staff very nice and helpful. Almost always had at least one person at front desk that spoke good ..."

Reviewed on 22 Jul 2026

Hotel Intercity Manaus
Da Vinci Hotel & Conventions by Easy Hotéis

Da Vinci Hotel & Conventions by Easy Hotéis

Rua Belo Horizonte, 240A - Adrianopolis Manaus AM
£36
4 Oct - 5 Oct
includes taxes & fees
Da Vinci Hotel & Conventions by Easy Hotéis
See all 238 properties in São Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a São Francisco travel package cost?
Starting from just £822, a travel package is your passport to low-cost travel. Build your own São Francisco getaway by selecting from our huge range of hotels, flights and rental cars.
If I'm not able to travel, can I cancel my São Francisco travel package?
If your holiday plans in São Francisco have changed, it's a relief to know that you can cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking was made more than 24 hours ago, your hotel, airline or car rental company may charge a cancellation fee. To learn more, check our Customer Service Portal.
How do I get a cheap travel package to São Francisco?
Combine your hotels and flights, toss in extras such as tours, and save with a São Francisco travel package. You won't just pick up awesome discounts on your escape — you'll have loads of choice within your reach too. When you book through Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels around the globe. Your unforgettable holiday begins right here, right now!
Does Expedia offer Book Now, Pay Later São Francisco holidays?
Your bank balance shouldn't prevent you from escaping on holiday, so Expedia has worked out a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book an incredible getaway without hurting your hip pocket. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your break. Consider one of these flexible payment options:
  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in convenient monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your holiday in multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan with Klarna.
Where should I stay in São Francisco?
Urban explorers come from all over to see Mindu Municipal Park and Teatro Amazonas in São Francisco. Book a room near these fantastic attractions and visit them at your leisure.
What are the top hotels in São Francisco?
Go Inn Manaus and ibis Manaus Aeroporto are a couple of the most sought-after hotels in São Francisco. Why not look up the facilities and rates at each and then make a decision?
How far in advance should I book my São Francisco holiday?
Browse Expedia to compare international fares as soon as you've got your travel dates. You can usually purchase a ticket up to a year in advance. If you don't see your preferred carrier, or you're booking late, fear not. Cheap tickets to São Francisco sometimes emerge within weeks of departure.
What does an Expedia São Francisco travel package include?
From flights and hotels to car rentals, Expedia can help you create a São Francisco package that works for you. Holidaying for a week or two? Look into a hotel, flight and rental car bundle. If you can only manage a quick getaway, a hotel and airfare deal could suit you better. Tours and activities can be added once you've made your booking. Our travel packages make it simple to plan and save.
What should I know before booking a São Francisco travel package?
A package can be easier on the hip pocket than separately booking everything you need for your escape. For example, bundle your hotels, flights and rental cars and save a pretty penny. Whatever your holiday plans, there's sure to be a package that's right for you.
Can I choose my airline with a São Francisco Expedia travel package?
You certainly can. Expedia has access to more than 550 partner airlines all over the world, so choose the carrier that best suits your budget needs.

Things to do

Maroaga Cave

Presidente Figueiredo Tour

£70
per adult
Presidente Figueiredo Tour
Manaus to Belem 5-Day Local Boat Trip

Manaus to Belem 5-Day Local Boat Trip

£112
per adult
Manaus to Belem 5-Day Local Boat Trip
A Whole Day in the Jungle

A Whole Day in the Jungle

£172
per adult
98% of travellers recommend
A Whole Day in the Jungle
See all activities in Manaus

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.