Title: Santo Tomé Travel Guide: Best of Santo Tomé, Santa Fe Province Travel 2026 | Expedia.co.uk [Hotels in Santo Tomé](https://expedia.co.uk/Santo-Tome-Hotels.d3000007162.Travel-Guide-Hotels)[Holiday Rentals in Santo Tomé](https://expedia.co.uk/Santo-Tome-Holiday-Rentals.d3000007162.Travel-Guide-HolidayRentals)[Santo Tomé Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santo-Tome.d3000007162.Car-Hire-Guide)[Santo Tomé Holidays](https://expedia.co.uk/Santo-Tome.d3000007162.Holidays-City-Breaks) # Santo Tomé Travel Guide ## Tourist Guide ![Tomando unos ricos mates argentinos y disfrutando del paisaje durante las vacaciones d invierno en San Carlos de Bariloche, Argentina. ](https://images.trvl-media.com/place/3000007162/78809fe8-a3db-4eb3-b838-1c5772d07683.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Tomando unos ricos mates argentinos y disfrutando del paisaje durante las vacaciones d invierno en San Carlos de Bariloche, Argentina. ](https://images.trvl-media.com/place/3000007162/b3bf40af-91f0-439c-adf7-23e041e57c7c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Sao Tome sign](https://images.trvl-media.com/place/3000007162/9f42a95e-f1c9-4f9b-a2ec-4b12c32bf2a1.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santo Tomé Things to do - Top hotels in Santo Tomé - Top Holiday Rentals in Santo Tomé ![Hotel de Campo Colon](https://images.trvl-media.com/lodging/5000000/4670000/4663300/4663285/86498d9c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel de Campo Colon Autopista Santa Fe - Rosario / KM 153 Santo Tomé Santa Fe Stay at this spa hotel in Santo Tomé. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions April 15 Stadium and Museo De Arte Contemporaneo ... 8.4/10 Very Good! (51 reviews) Hotel is OK, but not worth the price Pleasant and quiet rooms. Clean. But not a very friendly staff. The cafeteria has very few food/drink options, and it has a fly (the insect) problem. Oh, they overcharged my stay by 20% based on what Expedia quoted me, so read the bill before checking out... Reviewed on 5 Feb 2017 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=13%2F04%2F2026&endDate=14%2F04%2F2026&selected=4663285&PinnedHotelID=4663285&HadPinnedHotel=true®ionId=3000007162) [](https://expedia.co.uk/Hotel-Search?startDate=13%2F04%2F2026&endDate=14%2F04%2F2026&selected=4663285&PinnedHotelID=4663285&HadPinnedHotel=true®ionId=3000007162) ![InterTower Hotel](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/903afdd5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### InterTower Hotel San Jeronimo 2779 Santa Fe Santa Fe £78 2 Apr - 3 Apr Stay at this spa hotel in Santa Fe. Enjoy free breakfast, free Wi-Fi and a full-service spa. Popular attractions Museo Del Colegio De Medicos and Centro Cultural ... [](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=9845278&PinnedHotelID=9845278&HadPinnedHotel=true®ionId=3000007162) ![Castelar Hotel Santa Fe](https://images.trvl-media.com/lodging/37000000/36490000/36484400/36484365/92e5d52b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Castelar Hotel Santa Fe 25 de Mayo 2349 Santa Fe Santa Fe £43 2 Apr - 3 Apr Stay at this hotel in Santa Fe. Enjoy free breakfast, parking (surcharge) and a 24-hour front desk. Popular attractions Museo Del Colegio De Medicos and Ribera ... 7.4/10 Good! (98 reviews) The hotel is old, good location. They offer breakfast, good enough. Reviewed on 18 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=36484365&PinnedHotelID=36484365&HadPinnedHotel=true®ionId=3000007162) [See all 65 properties in Santo Tomé](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=31%2F03%2F2026&endDate=01%2F04%2F2026®ionId=3000007162) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Agustín 1 Apart](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/6427ef82_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Agustín 1 Apart 130 Gral. Pedro Ferré Parana Entre Ríos Stay at this aparthotel in Parana. Enjoy free Wi-Fi, parking (surcharge) and on-site spa services. Popular attractions Plaza de Mayo and Museu De Sitio are located ... 8.8/10 Excellent! (5 reviews) Everything about the place was great. Our only complaint was that the kettle didn't heat water so it was hard to make mate. Reviewed on 28 Feb 2026 [](https://expedia.co.uk/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) ![Cabañas Del Sauce II](https://images.trvl-media.com/lodging/106000000/105710000/105704100/105704087/dc811343_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cabañas Del Sauce II Paraná Entre Ríos Stay at this holiday home in Parana. Enjoy free Wi-Fi, a garden and cable/satellite TV service. Popular attractions Museo Provincial de Bellas Artes Dr. Pedro ... [](https://expedia.co.uk/Parana-Hotels-Vrbo-Property.h105704087.Hotel-Information) ![Departamento en Amarras Center Santa fe Capital la Mejor Zona Privada Puerto](https://images.trvl-media.com/lodging/102000000/101950000/101948900/101948867/6095a73c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Departamento en Amarras Center Santa fe Capital la Mejor Zona Privada Puerto Santa Fe de la Vera Cruz Santa Fe Stay at this apartment in Santa Fe. Enjoy air conditioning. Popular attractions Ribera Shopping and Museo Del Colegio De Medicos are located nearby. [](https://expedia.co.uk/Santa-Fe-Hotels-Departamento-En-Amarras-Center-Santa-Fe-Capital-La-Mejor-Zona-Privada-Puerto.h101948867.Hotel-Information) [See all properties in Santo Tomé](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=3000007162&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santo Tomé hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=2026-03-30&endDate=2026-03-31)[30 Mar - 31 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=2026-03-30&endDate=2026-03-31) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=2026-03-31&endDate=2026-04-01)[31 Mar - 1 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=2026-03-31&endDate=2026-04-01) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026)[10 Apr - 12 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000007162&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026) ### Popular places to visit #### El Museo Etnografico y Colonial Juan de Garay You can spend an afternoon browsing the exhibits at El Museo Etnografico y Colonial Juan de Garay during your travels in Santo Tomé. Experience the area's live music and museums. [](https://expedia.co.uk/El-Museo-Etnografico-Y-Colonial-Juan-De-Garay-Santo-Tome.d553248621532463761.Attraction) #### Museo De Arte Contemporaneo You can spend an afternoon exploring the galleries in Museo De Arte Contemporaneo during your travels in Santo Tomé. Experience the area's live music and museums. [](https://expedia.co.uk/Museo-De-Arte-Contemporaneo-Santo-Tome.d553248621532463760.Attraction) - Cities near Santo Tomé - Places of interest - [Museo Provincial de Bellas Artes Dr. Pedro E. Martinez ](https://expedia.co.uk/Museo-Provincial-De-Bellas-Artes-Dr-Pedro-E-Martinez-Parana.d553248621532463767.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app