Santo Tomas Holidays from £1,231
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Santo Tomas Holiday
Entertainment, food, art and more … There's a whole lot to discover with a Santo Tomas holiday package. And with the ability to easily customise your city break, it's guaranteed to be one that's hard to forget. If your trip to Santo Tomas includes some sightseeing, hit up well-known attractions like Zócalo, Angel of Independence Monument and Basilica of Our Lady of Guadalupe. Expedia will help you escape your daily routine. Tailor your holiday to Santo Tomas to match your travel style, whatever that may look like.
Grand Polanco Residencial
Reviewed on 26 Aug 2026
Where to stay in Santo Tomas
Roma Norte
Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.
Polanco
Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.
La Condesa
Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.
Historic Center
Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.
Reforma
Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.
Top hotels in Santo Tomas
Camino Real Aeropuerto Mexico
"The beds are super Comfortable the pillows are amazing. I love the smell in the lobby and the cleanliness of the facility"
Reviewed on 28 Aug 2026
Fiesta Americana Reforma
"It was a nice experience, the extras are awesome. Something not available at the USA hotels"
Reviewed on 28 Aug 2026
Hotel Zócalo Central
"Todo muy bien"
Reviewed on 28 Aug 2026
Frequently asked questions
How much does a Santo Tomas travel package cost?
If I'm not able to travel, can I cancel my Santo Tomas travel package?
How do I get a cheap travel package to Santo Tomas?
Does Expedia offer Book Now, Pay Later Santo Tomas holidays?
- Pay monthly holidays: Klarna has manageable monthly payment plans that suit all types of budgets, so you can lock in that well-earned holiday now.
- Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay for your holiday in multiple transactions.
- Low deposit holidays: When you want to grab an amazing deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you get what you want.
Where should I stay in Santo Tomas?
What are the top hotels in Santo Tomas?
How far in advance should I book my Santo Tomas holiday?
What does an Expedia Santo Tomas travel package include?
What should I know before booking a Santo Tomas travel package?
Can I choose my airline with a Santo Tomas Expedia travel package?
Things to do
Chapultepec Castle, Anthropology Museum & Forest Train
Mexico City Tourist Bus: Hop-On Hop-Off Service or Night Tour
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.