Santo Tomas Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Santo Tomas Holiday

Entertainment, food, art and more … There's a whole lot to discover with a Santo Tomas holiday package. And with the ability to easily customise your city break, it's guaranteed to be one that's hard to forget. If your trip to Santo Tomas includes some sightseeing, hit up well-known attractions like Zócalo, Angel of Independence Monument and Basilica of Our Lady of Guadalupe. Expedia will help you escape your daily routine. Tailor your holiday to Santo Tomas to match your travel style, whatever that may look like.

Price found within the past 48 hours. Click for updated prices.
  • Lobby
    Aug 5 - Aug 20

    Hotel PF + Flight

    Reforma
    15 nights
    3.5 star property
    9.0/10 - Wonderful (2,673 reviews)
    "The room was clean and friendly staff. No fridge in the room."
    Reviewed May 28, 2026
    Return • Manchester (MAN) - Mexico City (MEX)
    MAN - MEX • 1 stop MEX - MAN • 1 stop
    £2,086
    £1,372
    per traveller
    found 1 day ago
    Hotel PF
  • Rooftop terrace
    Aug 5 - Aug 20

    Casa Decu + Flight

    La Condesa
    15 nights
    4.0 star property
    9.4/10 - Exceptional (942 reviews)
    "What a lovely hotel. The staff were lovely and the location was perfect. This was a Claude recommendation and I'm so glad I went with it. Casa Decu was a lovely stay. The location was perfect for all the recommendations of places to go. The staff were lovely and incredibly helpful. I would definitely stay again. Finally, the terrace restaurant was a great place to get work done and enjoy the sunshine."
    Reviewed May 27, 2026
    Return • Manchester (MAN) - Mexico City (MEX)
    MAN - MEX • 1 stop MEX - MAN • 1 stop
    £3,264
    £1,632
    per traveller
    found 1 day ago
    Casa Decu
  • Premium Apartment, Balcony | Premium bedding, in-room safe, desk, laptop workspace
    Jul 28 - Aug 11

    Capitalia Aristoteles Polanco + Flight

    Polanco
    14 nights
    4.0 star property
    9.2/10 - Wonderful (191 reviews)
    "Nice apartment/hotel. Has all utensils in kitchen. Loved it "
    Reviewed May 16, 2026
    Return • Newcastle-upon-Tyne (NCL) - Mexico City (MEX)
    NCL - MEX • 2 stops MEX - NCL • 2 stops
    £2,507
    £1,574
    per traveller
    found 18 hours ago
    Capitalia Aristoteles Polanco
  • Luxury Suite, 1 King Bed, City View | Egyptian cotton sheets, premium bedding, down duvets
    Jul 23 - Jul 28

    Colima 71 Casa de Arte Hotel + Flight

    Roma Norte
    5 nights
    3.0 star property
    10/10 - Exceptional (47 reviews)
    "Perfect Roma Norte location, everything is close and in walking distance, the hotel is so pleasant, smiling faces all around, cute breakfast, very friendly staff, we have nothing but good things to say and great memories to cherish. Will we be back? You bet we will!"
    Reviewed March 7, 2026
    Return • London (LHR) - Mexico City (MEX)
    LHR - MEX • Direct MEX - LHR • Direct
    £3,066
    £1,996
    per traveller
    found 1 day ago
    Colima 71 Casa de Arte Hotel
  • Exterior
    Jul 28 - Aug 11

    Galeria Plaza Reforma + Flight

    Reforma
    14 nights
    4.0 star property
    9.4/10 - Exceptional (3,511 reviews)
    Return • Newcastle-upon-Tyne (NCL) - Mexico City (MEX)
    NCL - MEX • 2 stops MEX - NCL • 2 stops
    £2,862
    £1,915
    per traveller
    found 18 hours ago
    Galeria Plaza Reforma

Where to stay in Santo Tomas

Find the best Santo Tomas areas and neighborhoods for the activities you enjoy most. Learn more about Santo Tomas
The Cibeles fountain in Mexico City is an exact replica of the Cibeles fountain that is located in the Plaza de Cibeles in Madrid, Spain

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like MUCA Roma and Centro Cultural El Punto, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Find hotels in Roma Norte

Top hotels in Santo Tomas

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundable
The price is £106 per night from 20 Jun to 21 Jun
£106
20 Jun - 21 Jun
includes taxes & fees
8.8/10 Excellent! (13,039 reviews)
"El lugar es muy bonito"

Reviewed on 28 May 2026

Camino Real Aeropuerto Mexico
Barceló México Reforma

Barceló México Reforma

4.5 out of 5
Paseo De La Reforma 1 Mexico City
Fully refundableReserve now, pay when you stay
The price is £169 per night from 30 May to 31 May
£169
30 May - 31 May
includes taxes & fees
9.4/10 Exceptional! (5,378 reviews)
"Is great location . Clean and staff is super friendly .."

Reviewed on 28 May 2026

Barceló México Reforma
Hotel Zócalo Central

Hotel Zócalo Central

4 out of 5
Cinco de Mayo 61 Mexico City
Fully refundableReserve now, pay when you stay
The price is £130 per night from 31 May to 1 Jun
£130
31 May - 1 Jun
includes taxes & fees
9.8/10 Exceptional! (2,747 reviews)
"Hotel was amazing with friendly and helpful staff. Amazing views of the Zocalo made the experience even better will definitely be staying here again."

Reviewed on 27 May 2026

Hotel Zócalo Central
See all 5,894 properties in Santo Tomas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santo Tomas travel package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in Santo Tomas from just . And the more you bundle, the more money you save. The holiday of your dreams has never been so affordable.
If I'm not able to travel, can I cancel my Santo Tomas travel package?
It's hard to predict what the future holds, so it's comforting to know that you can cancel or change your Santo Tomas travel package. If your booking was made in the last 24 hours, you may be entitled to a refund. If it's an older booking, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal for more information.
How do I get a cheap travel package to Santo Tomas?
You'll save loads of cash if you bundle your hotels, car rentals and flights into a Santo Tomas travel package. Sometimes cheap means fewer options. But that's not the case with Expedia. We offer more than 550 partner airlines and 1,000,000 hotels throughout the world, which means you'll always have plenty of variety to choose from. Like to save even more? Add some fun activities to your package deal and unlock even bigger bargains! After all, travel is about more than just getting to your destination.
Does Expedia offer Book Now, Pay Later Santo Tomas holidays?
Your bank balance shouldn't get in the way of taking a holiday, so Expedia has devised a solution to help. Now that we've formed a partnership with online lender Klarna, it's easier than ever to book a fantastic getaway without draining your savings. Klarna offers flexible payment options at checkout that take the stress out of budgeting for your escape. Consider one of these flexible payment options:

  • Pay monthly holidays: Klarna has manageable monthly payment plans that suit all types of budgets, so you can lock in that well-earned holiday now.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay for your holiday in multiple transactions.
  • Low deposit holidays: When you want to grab an amazing deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you get what you want.

Where should I stay in Santo Tomas?
Stay where the action happens. Many travellers book hotels in the vicinity of top sights, such as Arena Ciudad de Mexico, Hospital de Jesus Nazareno and Planetario Luis Enrique Erro.
What are the top hotels in Santo Tomas?
Camino Real Aeropuerto Mexico and Fiesta Inn Aeropuerto Ciudad de Mexico are two of the most popular hotels in Santo Tomas. Why not look up the amenities and rates at each and then make up your mind?
How far in advance should I book my Santo Tomas holiday?
Earlier is always better. Airlines usually advertise flights up to 12 months ahead of departure, and this is a great opportunity to land some rock-bottom prices. Just been told you need to take your holiday time next week? No problem! Expedia are never short of fantastic deals to send you on the getaway of your dreams, at a price you can afford.
What does an Expedia Santo Tomas travel package include?
You can select from any combination of hotels, flights and rental cars. Once you've made your booking, you can add the fun stuff like experiences and tours. Want to pick your airfare class? That's also possible. The choice is yours when it comes to organising your ideal Santo Tomas getaway.
What should I know before booking a Santo Tomas travel package?
Get ready to save with an Expedia travel package. Bundle your flights, rental cars and hotels and pick up fabulous discounts. Hotels aren't your only option, though. Book with us and take your pick of beachside condos, chalets in the middle of mountains and even glamping tents!
Can I choose my airline with a Santo Tomas Expedia travel package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines globally. Our travel packages give you the flexibility to take your pick of available flight, hotel or activity options that fit your needs.

Popular places to visit

Paseo de la Reforma

Paseo de la Reforma

Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.

Paseo de la Reforma
Zócalo

Zócalo

This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.

Zócalo
Estadio Azteca

Estadio Azteca

See one of the world’s largest and most famous soccer stadiums, the host to two historic FIFA World Cup championships.

Estadio Azteca

Things to do

4a73fde4b9254c3a98b61177398906ed

Mexico City Tourist Bus: Hop-On Hop-Off Service or Night Tour

£10
per adult
Mexico City Tourist Bus: Hop-On Hop-Off Service or Night Tour
MEXICAN WRESTLING TOUR WITH TACOS AFTER SHOW N MEXICO CITY

Lucha Libre Mexican Wrestling Tour in Mexico City

£45
per traveller
Lucha Libre Mexican Wrestling Tour in Mexico City
See all activities in Mexico City

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.