Santo Domingo Holidays from £1,205
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Your Santo Domingo Holiday
Your next great escape is calling with a holiday package to Santo Domingo. Fun, food and nothing but good times — you're sure to find it in this neighbourhood. Kick start your trip to Santo Domingo by checking out nearby attractions such as Estadio Azteca, Estadio Olimpico and Jardin del Arte. Stop dreaming and start doing. When you're ready to book your holiday to Santo Domingo, Expedia is here to help.
Price found within the past 48 hours. Click for updated prices.
Wynwood House Sinaloa
Roma Norte
£2,011
per person
27 Oct - 3 Nov
found 1 day ago
Return direct flight included
London (LON) to Mexico City (MEX)
6.6/10 (4 reviews)
The rooms are great, very new and super equipped. My issue was that apparently they doble booked my room. So at 12 am a group walked into the room. Which was unsafe and uncomfortable for everyone! Very unsafe and irresponsible
Reviewed on 3 Nov 2023
AR 218 Hotel by ULIV
La Condesa
£1,751
per person
27 Oct - 3 Nov
found 1 day ago
Return direct flight included
London (LHR) to Mexico City (MEX)
9.6/10 Exceptional! (1,271 reviews)
Good stay at a good price. Very comfortable and spacious room, and location of the hotel is perfect. Inexpensive and quick uber rides to many major attractions, and walking distance from many good restaurants and parks. Would stay here again
Reviewed on 14 Sept 2026
Where to stay in Santo Domingo
Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo
Roma Norte
Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.
Polanco
Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.
La Condesa
Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.
Historic Center
2 out of top 10 points of interest in this area
Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.
Reforma
1 out of top 10 points of interest in this area
Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.
Top hotels in Santo Domingo
Camino Real Aeropuerto Mexico
Mexico City
Fully refundable
£113
4 Oct - 5 Oct
includes taxes & fees
8.8/10 Excellent! (13,974 reviews)
"Overall it was a pleasant and stress free stay at the airport location."
Reviewed on 15 Sept 2026
Fiesta Americana Reforma
Paseo De La Reforma 80 Mexico City CDMX
Fully refundableReserve now, pay when you stay
£105
16 Oct - 17 Oct
includes taxes & fees
Barceló México Reforma
Paseo De La Reforma 1 Mexico City
Fully refundableReserve now, pay when you stay
£131
18 Sept - 19 Sept
includes taxes & fees
9.4/10 Exceptional! (5,531 reviews)
"I Ike’s that when I called front desk to ask for something, they were quick to respond."
Reviewed on 15 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santo Domingo travel package cost?
Say yes to new adventures with our Santo Domingo travel packages, which start from a low £1,205. Select the hotels and flights that match your travel plans. Then, add on a few tours or experiences for an incredible adventure.
If I'm not able to travel, can I cancel my Santo Domingo travel package?
Plans can change in a flash, so yes, you can. You may be able to amend or cancel your Santo Domingo travel package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still cancel or make changes, but your airline, hotel or car rental company may impose a charge. Need more information? Visit our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to Santo Domingo?
Bundling your hotel and flight with Expedia won't just save precious time — it'll save you a tidy sum too. A Santo Domingo travel package makes it a cinch to arrange your ideal trip. With more than 550 airlines across the world to choose from, finding convenient flights that fit your busy schedule won't be a hassle. On top of that, we have over 1,000,000 hotels globally to select from. Now that's what you call choice. No matter who you are, Expedia puts more of the world within your reach.
Does Expedia offer Book Now, Pay Later Santo Domingo holidays?
Good news! We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply click on the payment plan that works for you during the checkout process and take away the stress of budgeting for your trip. Don't forget to bundle your flights, car hire and accommodation with Expedia to get the biggest bang for your holiday buck. Browse our flexible payment options below:
- Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's manageable monthly instalment plans. If paying just a little each month sounds right for you, choose this option during the checkout process.
- Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your trip in multiple transactions.
- Low deposit holidays: When you stumble on an unbeatable deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you secure your getaway.
Where should I stay in Santo Domingo?
Make sightseeing a breeze by staying in a hotel just around the corner from Santo Domingo's iconic attractions. Zócalo and Basilica of Our Lady of Guadalupe are two of the best in this neighbourhood.
What are the top hotels in Santo Domingo?
If this will be your first time in Santo Domingo, reserve a room at Camino Real Aeropuerto Mexico or Fiesta Inn Aeropuerto Ciudad de Mexico. Both will make you feel at home and are popular options with many travellers.
How far in advance should I book my Santo Domingo holiday?
Reserving your seat early with Expedia means one less thing to worry about. Most air carriers advertise prices up to 12 months in advance. Generally, this is the cheapest time to book. If circumstances have left you booking late, low prices to Santo Domingo are still known to appear a few weeks before departure.
What does an Expedia Santo Domingo travel package include?
It all depends on what sort of trip you have in mind. Santo Domingo travel deals can include hotels, car rentals and flights. You can mix and match to create the bundle that fits your needs. You can also add on activities and experiences after you've booked to get even bigger discounts.
What should I know before booking a Santo Domingo travel package?
Find deals that suit your budget with an Expedia package. Airfares, hotels, rental cars — we have everything you need to plan your escape. You'll save a packet just for combining your bookings. Whether you're embarking on a winter adventure or sipping cocktails on a beach, your perfect holiday is just clicks away.
Can I choose my airline with a Santo Domingo Expedia travel package?
Yes, and with over 550 airlines to pick from throughout the world, you're spoiled for choice. Browse the available options and find out which airline best suits your needs and budget.
Things to do
Mexico City Tourist Bus: Hop-On Hop-Off Service or Night Tour
£12
per adult
84% of travellers recommend
Chapultepec Castle, Anthropology Museum & Forest Train
£14
per adult
100% of travellers recommend
Guadalupe Shrine & Teotihuacan Pyramids Tour
£62
per adult
90% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.