
Santo Domingo Holidays from £787
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Your Santo Domingo Holiday
Your next great escape is calling with a holiday package to Santo Domingo. Fun, food and nothing but good times — you're sure to find it in this neighbourhood. Kick start your trip to Santo Domingo by checking out nearby attractions such as Estadio Azteca, Estadio Olimpico and Jardin del Arte. Stop dreaming and start doing. When you're ready to book your holiday to Santo Domingo, Expedia is here to help.

Casa Decu
Reviewed on 3 Sept 2025

Gran Hotel Ciudad de Mexico Zocalo View
Reviewed on 11 Sept 2025

Historico Central Hotel
Reviewed on 10 Sept 2025

Zocalo Central & Rooftop Mexico City
Reviewed on 8 Sept 2025

Maria Condesa
Reviewed on 7 Sept 2025
Where to stay in Santo Domingo

Polanco
Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.
Top hotels in Santo Domingo

Camino Real Aeropuerto Mexico
Reviewed on 9 Sep 2025

Barceló México Reforma
Reviewed on 9 Sep 2025

Camino Real Polanco Mexico
Reviewed on 9 Sep 2025
Frequently asked questions
Popular places to visit

Paseo de la Reforma
Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.

Zócalo
This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.

Basilica of Our Lady of Guadalupe
Mexico’s patron saint, the Virgin of Guadalupe, is believed to have appeared on the site of this church, making it an important pilgrimage site for many Catholics.
Things to do

Tolantongo Caves Full Day Tour from Mexico City

Teotihuacan Early or Afternoon Access Guided Tour with No Crowds
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.