
Santiago Matatlán Holidays from £1,343
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Santiago Matatlán Holiday
Our Santiago Matatlán holiday packages give you the power to customise your own adventure. Tailor your journey to your needs and interests and make every moment count in this fabulous city. Fill your trip to Santiago Matatlán with visits to its top attractions. Where to first? You won't want to miss Mitla. No matter your travel plans or the size of your budget, putting together a tailored Santiago Matatlán holiday is simple with Expedia.
Top Santiago Matatlán Flight + Hotel Deals

Casa Quiote Hotel Boutique City Center based - Adults Only
Reviewed on 27 Jun 2026

Casa De Sierra Azul
Reviewed on 25 Jun 2026

Grand Fiesta Americana Oaxaca
Reviewed on 25 Jun 2026

Casa Antonieta
Reviewed on 7 Jun 2026

Ébano by PB
Reviewed on 20 Jun 2026
Santiago Matatlán Essential Information
Language | Spanish |
|---|---|
Currency | Mexican pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Xoxocotlan Intl. Airport (OAX) |
Population | 3,400 |
Max Temp Winter | 21ºC |
Max Temp Summer | 24ºC |
Top Sights | Tlacolula Market, Mitla Archaeological Site and Ancient Mitla |
Top hotels in Santiago Matatlán

Hotel Hacienda
"Hacienda offered comfortable clean rooms and helpful staff. Would love to have a refrigerator next time."
Reviewed on 26 Jun 2026

Fiesta Inn Oaxaca
"Shower needs to be fix. The shower drain was clog."
Reviewed on 14 Jun 2026

Maria Ines Hotel Suite
"It is clean, the workers are friendly and respectful. The court yard is beautiful. I'm female traveling alone. I felt very safe and the airport is less than 2 miles, about 5 minutes from the hotel. There is and Italian restaurant next door. Or you can download didifood app. Very convenient!"
Reviewed on 16 Jun 2026
What to do in Santiago Matatlán

Enjoy Medio Día de Hierve el Agua and a mezcal factory.

Distillery Tour and Agave Fields by Mal de Amor Mezcal
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.











