Title: Santiago Island Travel Guide: Best of Santiago Island, Galápagos Travel 2025 | Expedia.co.uk [Hotels in Santiago Island](https://expedia.co.uk/Santiago-Island-Hotels.d6336381.Travel-Guide-Hotels)[Holiday Rentals in Santiago Island](https://expedia.co.uk/Santiago-Island-Holiday-Rentals.d6336381.Travel-Guide-HolidayRentals)[Flights to Santiago Island](https://expedia.co.uk/Cheap-Flights-To-Santiago-Island.d6336381.Travel-Guide-Flights)[Santiago Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santiago-Island.d6336381.Car-Hire-Guide)[Santiago Island Holidays](https://expedia.co.uk/Santiago-Island.d6336381.Holidays-City-Breaks) # Santiago Island Travel Guide ## Tourist Guide ![Photo by Sarah Mack](https://mediaim.expedia.com/destination/2/308490f359ba976facce5482e0592a56.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Sarah Mack](https://mediaim.expedia.com/destination/2/308490f359ba976facce5482e0592a56.jpg) ![Photo by marie harel](https://mediaim.expedia.com/destination/2/451a1cbb504e41a820712cf863832cc6.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by marie harel](https://mediaim.expedia.com/destination/2/451a1cbb504e41a820712cf863832cc6.jpg) ![Photo by Luis Felipe](https://mediaim.expedia.com/destination/2/908bf3704094b5b433b939554890af97.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Luis Felipe](https://mediaim.expedia.com/destination/2/908bf3704094b5b433b939554890af97.jpg) ![Photo by marie harel](https://mediaim.expedia.com/destination/2/81e549d84daeca12863806d94baf9fe7.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by marie harel](https://mediaim.expedia.com/destination/2/81e549d84daeca12863806d94baf9fe7.jpg) ![Photo by Diagnosis Wanderlust](https://mediaim.expedia.com/destination/2/8a7daab54ac39a69679b638fdf4f92e3.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Diagnosis Wanderlust](https://mediaim.expedia.com/destination/2/8a7daab54ac39a69679b638fdf4f92e3.jpg) ## Visit Santiago Island Things to do - Top Holiday Rentals in Santiago Island ![Villa Galapagos](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/369f220c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Villa Galapagos Fragata y Av. Seymour, Puerto Ayora Stay at this holiday home in Puerto Ayora. Enjoy free Wi-Fi, daily housekeeping and premium TV channels. Popular attractions Fishing Piers and Gus Angermeyer ... "着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。" Reviewed on 16 Aug 2019 [](https://expedia.co.uk/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information) ![Galapagos and Beyond](https://images.trvl-media.com/lodging/100000000/99530000/99523000/99522986/5d3c0d78_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Galapagos and Beyond Indefatigable entre Duncan & Juan, Puerto Ayora, Galapagos Stay at this 5-star luxury condo in Puerto Ayora. Enjoy free breakfast, free Wi-Fi and hot springs on-site. Popular attractions Fishing Piers and Las Ninfas ... 10/10 Exceptional! (6 reviews) "Great stay! The rooms, the service, the breakfast, everything was great. Definitely stay here" Reviewed on 26 May 2025 [](https://expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-And-Beyond.h99522986.Hotel-Information) ![Galapagos Coliving Ecuador Casa Tuna](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/992ac688_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Galapagos Coliving Ecuador Casa Tuna Miconia, Puerto Ayora, Galápagos Stay at this 3-star business-friendly apartment in Puerto Ayora. Enjoy free Wi-Fi, free parking and balconies. Popular attractions Fishing Piers and Gus Angermeyer ... [](https://expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information) [See all 388 properties in Galápagos](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=1371&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santiago Island hotel availability [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-27&endDate=2025-09-28) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-27&endDate=2025-09-28) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-27&endDate=2025-09-28) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-27&endDate=2025-09-28)[27 Sept - 28 Sept](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-27&endDate=2025-09-28) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-28&endDate=2025-09-29) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-28&endDate=2025-09-29) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-28&endDate=2025-09-29) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-28&endDate=2025-09-29)[28 Sept - 29 Sept](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=2025-09-28&endDate=2025-09-29) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) [Next weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025)[3 Oct - 5 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6336381&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) ## Explore a world of travel with Expedia - 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[Thrifty Car Rental Rental Cars in North Seymour Island](https://www.expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-North-Seymour-Island.d6336659-c45.Car-Rental-Guide-Suppliers) - [Top Rent a Car Rental Cars in Daphne Islands](https://www.expedia.co.uk/Top-Rent-A-Car-Car-Rentals-In-Daphne-Islands.d6336492-c1028.Car-Rental-Guide-Suppliers) - [Top Rent a Car Rental Cars in Santa Cruz Island](https://www.expedia.co.uk/Top-Rent-A-Car-Car-Rentals-In-Santa-Cruz-Island.d6053670-c1028.Car-Rental-Guide-Suppliers) - [Baltra Holiday Rentals](https://www.expedia.co.uk/Baltra-Holiday-Rentals.d6223000.Travel-Guide-HolidayRentals) - [Galápagos Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Holiday-Rental-Destinations) - [Isabela Island Holiday Rentals](https://www.expedia.co.uk/Isabela-Island-Holiday-Rentals.d6085329.Travel-Guide-HolidayRentals) - [Santa Rosa Holiday Rentals](https://www.expedia.co.uk/Santa-Rosa-Holiday-Rentals.d6053725.Travel-Guide-HolidayRentals) - [Things to do in Baltra](https://www.expedia.co.uk/Things-To-Do-In-Baltra.d6223000.Travel-Guide-Activities) - [Things to do in Galápagos](https://www.expedia.co.uk/Things-To-Do-In-Galapagos.d1371.Travel-Guide-Activities) - [Things to do in Isabela Island](https://www.expedia.co.uk/Things-To-Do-In-Isabela-Island.d6085329.Travel-Guide-Activities) - [Things to do in North Seymour Island](https://www.expedia.co.uk/Things-To-Do-In-North-Seymour-Island.d6336659.Travel-Guide-Activities) - [Things to do in Santa Cruz Island](https://www.expedia.co.uk/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities) - Cities near Santiago Island - Places of interest - [Galápagos National Park](https://expedia.co.uk/Galapagos-National-Park-Galapagos.d6112453.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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